Addison's disease overview: Difference between revisions
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==Overview== | ==Overview== | ||
'''Addison's disease''' is a rare [[endocrine]] disorder in which the [[adrenal gland]] produces insufficient amounts of [[steroid hormone]]s ([[glucocorticoid]]s and often [[mineralocorticoid]]s). It may develop in children as well as adults, and may occur as the result of a large number of underlying causes. <ref>[http://www.niddk.nih.gov/health/endo/pubs/addison/addison.htm NIH Publication No. 04–3054: Addison's disease. A work by Endocrine and Metabolic Diseases Information Service. National Institute for Health. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2004 June]</ref> | '''Addison's disease''' is a rare [[endocrine]] disorder in which the [[adrenal gland]] produces insufficient amounts of [[steroid hormone]]s ([[glucocorticoid]]s and often [[mineralocorticoid]]s). It may develop in children as well as adults, and may occur as the result of a large number of underlying causes. <ref>[http://www.niddk.nih.gov/health/endo/pubs/addison/addison.htm NIH Publication No. 04–3054: Addison's disease. A work by Endocrine and Metabolic Diseases Information Service. National Institute for Health. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2004 June]</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Addison's disease is a rare endocrine disorder in which the adrenal gland produces insufficient amounts of steroid hormones (glucocorticoids and often mineralocorticoids). It may develop in children as well as adults, and may occur as the result of a large number of underlying causes. [1]
The condition is named after Dr Thomas Addison, the British physician who first described the condition in his 1855 On the Constitutional and Local Effects of Disease of the Suprarenal Capsules.[2] The adjective "Addisonian" is used for features of the condition, as well as patients with Addison's disease.[3]
The condition is generally diagnosed with blood tests, medical imaging and additional investigations.[3] Treatment is with replacement of the hormones (oral hydrocortisone and fludrocortisone). If the disease is caused by an underlying problem, this is addressed. Regular follow-up and monitoring for other health problems is necessary.[3]
References
- ↑ NIH Publication No. 04–3054: Addison's disease. A work by Endocrine and Metabolic Diseases Information Service. National Institute for Health. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2004 June
- ↑ Thomas Addison. On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules (HTML reprint). London: Samuel Highley.
- ↑ 3.0 3.1 3.2 Ten S, New M, Maclaren N (2001). "Clinical review 130: Addison's disease 2001". J. Clin. Endocrinol. Metab. 86 (7): 2909–22. PMID 11443143.