Suppurative thrombophlebitis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Natural history, Complications and Prognosis
The most common complication of suppurative thrombophlebitis is metastatic septic foci spreading to different organs of the body. Examples of these complications include:
- Septic shock
- Sustained sepsis
- Infective endocarditis
- Septic emboli to the central nervous system
- Septic pulmonary emboli
- Osteomyelitis
- Septic arthritis
- Arteritis
Complications of suppurative thrombophlebitis occur in one third of all patients with catheter-associated peripheral septic phlebitis, with the most severe complications caused by S. aureus.[1]
Septic thrombophlebitis of the intracranial dural sinuses has a very high mortality rate, compared to pelvic and jugular thrombophlebitis. Lemierre syndrome has a documented mortality rate of 6.4%.[2]
References
- ↑ Arnow PM, Quimosing EM, Beach M (1993). "Consequences of intravascular catheter sepsis". Clin Infect Dis. 16 (6): 778–84. PMID 8329510.
- ↑ Chirinos JA, Lichtstein DM, Garcia J, Tamariz LJ (2002). "The evolution of Lemierre syndrome: report of 2 cases and review of the literature". Medicine (Baltimore). 81 (6): 458–65. PMID 12441902.