Sulfamethizole

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Sulfamethizole
Systematic (IUPAC) name
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- benzenesulfonamide
Identifiers
CAS number 144-82-1
ATC code B05CA04 D06BA04, J01EB02, S01AB01
PubChem 5328
DrugBank APRD00684
Chemical data
Formula C9H10N4O2S2 
Mol. mass 270.333 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 98–99%
Metabolism  ?
Half life 3–8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

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Sulfamethizole

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Sulfamethizole is a sulfonamide antibiotic.

External links

  • Ratanajamit C, Skriver M, Nørgaard M, Jepsen P, Schønheyder H, Sørensen H (2003). "Adverse pregnancy outcome in users of sulfamethizole during pregnancy: a population-based observational study.". J Antimicrob Chemother 52 (5): 837-41. PMID 14519675.
  • Kerrn M, Frimodt-Møller N, Espersen F (2003). "Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model.". Antimicrob Agents Chemother 47 (3): 1002-9. PMID 12604534.
  • Watanabe H, Hastings J (1990). "Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine.". Biochim Biophys Acta 1017 (3): 229-34. PMID 2372557.




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