Hepatosplenomegaly
| Hepatosplenomegaly | |
 | |
|---|---|
| Hepatosplenomegaly | |
| ICD-10 | R16.2 |
| ICD-9 | 571.8, 789.1, 789.2 |
| MedlinePlus | 003275 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hepatosplenomegaly is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).
Differential Diagnosis of Causes of Hepatosplenomegaly
In alphabetical order. [1] [2]
- Abdominal typhoid fever
- Amebiasis
- Amyloidosis
- Bang's Disease
- Banti's Disease
- Bilharziosis
- Brucellosis
- Budd-Chiari Syndrome
- Chronic myelogenous leukemia
- Chronic myelosis
- Cirrhosis
- Congested liver
- Cystic Fibrosis
- Cystic liver
- Cytomegalovirus
- Dengue
- Drug-induced jaundice
- Echinococcosis
- Extrahepatic cholestasis
- Familial hypercholesterolemia
- Fatty liver
- Felty's Syndrome
- Galactosemia
- Gaucher's Disease
- Glucose-6 phosphate deficiency
- Hemochromatosis
- Histiocytosis X
- Histoplasmosis
- Hodgkin's Lymphoma
- Idiopathic thrombocythemia
- Immune-hemolytic anemia
- Infectious mononucleosis (Glandular fever) due to Epstein-Barr virus
- Juvenile myelomonocytic leukemia
- Leishmaniais
- Leptospirosis
- Letterer-Siwe Disease
- Leukemia
- Lymphoma
- Malaria
- Miliary tuberculosis
- Morbus haemolyticus neonatorum
- Moschcowitz microangiopathy
- Multiple liver metastases
- Neimann-Pick Disease
- Neuroblastoma
- Pfaundler-Hurler Syndrome
- Polycythemia
- Primary biliary cirrhosis
- Osler's Disease
- Osteomyelosclerosis
- Primary/acute HIV infection
- Recurrent pulmonary embolism
- Relapsing fever
- Sarcoidosis
- Schistosomiasis
- Sickle Cell Anemia
- Sideroblastic anemia
- Still's Disease
- Stones
- Systemic Juvenile Idiopathic Arthritis
- Thalassemia
- Type IV glycogenesis
- Venous thrombosis
- Viral hepatitis
- Visceral leishmaniasis
- Wilson's Disease
Related Chapters
References
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
External links
- 1516961800 at GPnotebook
- vii/h/HEPATOSPLENOMEGALY article at GE's Medcyclopaedia
Symptoms and signs: circulatory (R00–R03, 785) | |||||||
|---|---|---|---|---|---|---|---|
| Cardiovascular |
| ||||||
| Myeloid/blood |
| ||||||
Symptoms and signs: respiratory system (R04–R07, 786) | |
|---|---|
| Hemorrhage | * Epistaxis |
| Abnormalities of breathing | ; Respiratory sounds: |
| Other | * Asphyxia |
| Chest, general | * Chest pain |
Symptoms and signs: digestive system and abdomen (R10–R19, 787,789) | |||||
|---|---|---|---|---|---|
| GI tract |
| ||||
| Accessory | Hepatosplenomegaly/Hepatomegaly Jaundice | ||||
| Abdominopelvic | Ascites | ||||
| Abdominal – general | |||||
Symptoms and signs: skin and subcutaneous tissue (R20-R23, 782) | |
|---|---|
| Disturbances of skin sensation | Hypoesthesia - Paresthesia - Hyperesthesia |
| Other | Rash - Cyanosis - Pallor - Flushing - Petechia - Desquamation - Induration - Diaphoresis |
Symptoms and signs: nervous and musculoskeletal systems (R25-R29, 781) | |
|---|---|
| Abnormal involuntary movements (see also movement disorders) | Tremor - Spasm - Fasciculation - Athetosis |
| Gait abnormality | Scissor gait - Antalgic gait - Cerebellar ataxia - Festinating gait - Pigeon gait - Propulsive gait - Steppage gait - Stomping gait - Spastic gait - Myopathic gait - Magnetic gait - Trendelenburg gait |
| Lack of coordination | Ataxia (Cerebellar ataxia, Sensory ataxia) - Dysmetria - Dysdiadochokinesia - Hypotonia |
| Other | Tetany - Meningism - Hyperreflexia - Opisthotonus - Abnormal posturing - Hemispatial neglect |
Symptoms and signs: urinary system (R30-R39, 788) | |
|---|---|
| General | Renal colic - Dysuria - Vesical tenesmus - Urinary incontinence - Urinary retention - Oliguria - Polyuria - Nocturia - Extravasation of urine - Extrarenal uremia |
Symptoms and signs: cognition, perception, emotional state and behaviour (R40-R46, 780-781) | |
|---|---|
| General | Anxiety - Somnolence - Coma - Amnesia (Anterograde amnesia, Retrograde amnesia) - Dizziness/Vertigo |
| Olfaction | Anosmia - Parosmia |
| Taste | Ageusia - Parageusia |
Symptoms and signs: Speech and voice (R47-R49, 784) | |
|---|---|
| Aphasia/Dysphasia | Expressive aphasia - Receptive aphasia - Conduction aphasia |
| Other speech disturbances | Dysarthria - Schizophasia |
| Symbolic dysfunctions | Dyslexia - Alexia - Agnosia (Prosopagnosia) - Apraxia - Acalculia - Agraphia |
| Voice disturbances | Dysphonia - Aphonia |
Symptoms and signs: general (R50-R69, 780-789) | |
|---|---|
| General | Fever (Hyperpyrexia) - Headache - Chronic pain - Malaise/Fatigue (Asthenia, Debility) - Fainting (Vasovagal syncope) - Febrile seizure - Shock (Cardiogenic shock) - Lymphadenopathy - Edema (Peripheral edema, Anasarca) - Hyperhidrosis (Sleep hyperhidrosis) - Delayed milestone - Failure to thrive - Short stature (Idiopathic) - food and fluid intake (Anorexia, Polydipsia, Polyphagia) - Cachexia - Xerostomia - Clubbing - Tenderness |
Symptoms and signs: Symptoms concerning nutrition, metabolism and development (R62–R64, 783) | |
|---|---|
| Ingestion/Weight | |
| Growth | Delayed milestone • Failure to thrive • Short stature (e.g., Idiopathic) |
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