Amoebic liver abscess laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Laboratory tests consistent with diagnosis of amoebic liver abscess include complete blood count, ESR, C-reactive protein, liver function tests, and stool examination.

Laboratory Findings

Laboratory tests consistent with diagnosis of amoebic liver abscess include:

Lab Test	Findings
Complete blood picture	Hemoglobin <10g/dl Leukocytosis Neutrophilia
ESR and CRP	Elevated ESR and C-reactive protein
Liver function tests	Acute infection Elevated aspartate aminotransferase Normal alkaline phosphatase Chronic infection Elevated aspartate aminotransferase Normal alkaline phosphatase Hyperbilirubinemia and hypoalbuminemia is more common in amoebic liver abscess.
Stool examination	Microscopic stool examination for cysts Microscopic stool examination for cysts is of little value due to infection with non-pathogenic strain of E dispar If positive it suggests the diagnosis of amoebiasis. Cysts must be differentiated from Entamoeba hartmanni, Endolimax nana, and Entamoeba coli. Examination for trophozoites As the trophozoites are very sensitive and may be excreted intermittently, at least three fresh specimens are taken. A combination of iodine-stained concentrates, trichome-stained preparations, and wet mount are used. Trophozoites must be differentiated with neutrophils. Findings suggestive of amoebic colitis include: Charcot-leyden crystal protein Positive test for heme A paucity of neutrophils