Stevens-Johnson syndrome causes: Difference between revisions

Jump to navigation Jump to search
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Stevens-Johnson syndrome}}
{{Stevens-Johnson syndrome}}
{{CMG}}
{{CMG}}; {{AE}} {{AHS}}


== Overview ==
== Overview ==
Stevens-Johnson Syndrome is caused by drug reactions in the majority of the cases although it is also seen in certain viral and bacterial infections, and certain malignancies. Most commonly implicated drugs include sulfa drugs, Allopurinol, Anti-epileptics (phenobarbital, carbamazepine, lamotrigine), antibiotics (for example Penicillin), and [[NSAIDs]]. Infections that are associated with SJS may include HIV, [[HSV]], [[Mumps]], [[Mycoplasma]], [[Mycobacteria]], [[Hepatitis]] and streptococcal Infection.


==Causes==
==Causes==
There are different triggers for Stevens Johnson Syndrome Include Drug induced, Infections, Some systemic and Autoimmune disease among others.
There are different triggers for Stevens-Johnson Syndrome Include drug-induced, infections, some systemic and [[Autoimmune]] disease among others.


=== Drug Induced SJS: ===
=== Drug Induced SJS: ===
Line 74: Line 75:
* [[Histoplasmosis]]
* [[Histoplasmosis]]
* [[Epstein-Barr virus]]
* [[Epstein-Barr virus]]
Some bacterial infections may be associated with SJS, including following:
Some bacterial infections may be associated with SJS, including following<ref>{{cite web |url=http://dx.doi.org/10.1590/1806-9282.62.05.468 |title=Stevens-Johnson syndrome and toxic epidermal necrolysis: a review |format= |work= |accessdate=}}</ref>:
* Group A- Beta Hemolytic streptococci
* [[Group A- Beta Hemolytic streptococci]]
* Mycoplasma Pneumoniae
* [[Mycoplasma Pneumoniae]]<ref name="pmid20118388">{{cite journal| author=Wetter DA, Camilleri MJ| title=Clinical, etiologic, and histopathologic features of Stevens-Johnson syndrome during an 8-year period at Mayo Clinic. | journal=Mayo Clin Proc | year= 2010 | volume= 85 | issue= 2 | pages= 131-8 | pmid=20118388 | doi=10.4065/mcp.2009.0379 | pmc=2813820 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20118388  }} </ref>
* Diptheria
* [[Diphtheria|Diptheria]]
* Brucellosis
* [[Brucellosis]]
* Typhoid fever
* [[Typhoid fever]]
* Mycobacteria
* [[Mycobacterium|Mycobacteria]]


=== Other Causes ===
=== Other Causes ===

Latest revision as of 15:36, 15 September 2018

Stevens-Johnson syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Stevens-Johnson Syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Stevens-Johnson syndrome causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Stevens-Johnson syndrome causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Stevens-Johnson syndrome causes

CDC on Stevens-Johnson syndrome causes

Stevens-Johnson syndrome causes in the news

Blogs on Stevens-Johnson syndrome causes

Directions to Hospitals Treating Stevens-Johnson syndrome

Risk calculators and risk factors for Stevens-Johnson syndrome causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anila Hussain, MD [2]

Overview

Stevens-Johnson Syndrome is caused by drug reactions in the majority of the cases although it is also seen in certain viral and bacterial infections, and certain malignancies. Most commonly implicated drugs include sulfa drugs, Allopurinol, Anti-epileptics (phenobarbital, carbamazepine, lamotrigine), antibiotics (for example Penicillin), and NSAIDs. Infections that are associated with SJS may include HIV, HSV, Mumps, Mycoplasma, Mycobacteria, Hepatitis and streptococcal Infection.

Causes

There are different triggers for Stevens-Johnson Syndrome Include drug-induced, infections, some systemic and Autoimmune disease among others.

Drug Induced SJS:

One of the main triggers to cause SJS is the drug induced reaction

Infection Induced SJS

SJS can be caused by infections, usually following viral infections:

Some bacterial infections may be associated with SJS, including following[8]:

Other Causes

References

  1. Levi N, Bastuji-Garin S, Mockenhaupt M, Roujeau JC, Flahault A, Kelly JP; et al. (2009). "Medications as risk factors of Stevens-Johnson syndrome and toxic epidermal necrolysis in children: a pooled analysis". Pediatrics. 123 (2): e297–304. doi:10.1542/peds.2008-1923. PMID 19153164.
  2. Halevy S, Ghislain PD, Mockenhaupt M, Fagot JP, Bouwes Bavinck JN, Sidoroff A; et al. (2008). "Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel". J Am Acad Dermatol. 58 (1): 25–32. doi:10.1016/j.jaad.2007.08.036. PMID 17919772.
  3. Hällgren J, Tengvall-Linder M, Persson M, Wahlgren CF (2003). "Stevens-Johnson syndrome associated with ciprofloxacin: a review of adverse cutaneous events reported in Sweden as associated with this drug". J Am Acad Dermatol. 49 (5 Suppl): S267–9. doi:10.1016/S0190. PMID 14576649.
  4. Medsafe Data Sheet March 8, 2005. Accessed April 26, 2007.
  5. Raksha MP, Marfatia YS (2008). "Clinical study of cutaneous drug eruptions in 200 patients". Indian J Dermatol Venereol Leprol. 74 (1): 80. PMID 18193504.
  6. Fagot J, Mockenhaupt M, Bouwes-Bavinck J, Naldi L, Viboud C, Roujeau J (2001). "Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis". AIDS. 15 (14): 1843–8. doi:10.1097/00002030-200109280-00014. PMID 11579247.
  7. Devi K, George S, Criton S, Suja V, Sridevi P (2005). "Carbamazepine--the commonest cause of toxic epidermal necrolysis and Stevens-Johnson syndrome: a study of 7 years". Indian J Dermatol Venereol Leprol. 71 (5): 325–8. PMID 16394456.
  8. "Stevens-Johnson syndrome and toxic epidermal necrolysis: a review".
  9. Wetter DA, Camilleri MJ (2010). "Clinical, etiologic, and histopathologic features of Stevens-Johnson syndrome during an 8-year period at Mayo Clinic". Mayo Clin Proc. 85 (2): 131–8. doi:10.4065/mcp.2009.0379. PMC 2813820. PMID 20118388.
  10. Stevens-Johnson Syndrome-emerg/555 at eMedicine


Template:WikiDoc Sources