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==Overview==
==Overview==


The hallmark of squamous cell carcinoma of the lung is [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]] may be suggestive of squamous cell carcinoma of the lung. Symptoms related with squamous cell carcinoma of the lung will vary depending on the size and location of the tumor. Common symptoms of squamous cell carcinoma of the lung may also include [[shortness of breath]], [[fatigue]], and [[chest pain]]. Less common symptoms of squamous cell carcinoma of the lung, include: bone pain, fatigue, dizziness, dysphagia, and numbness in extremities.
The [[hallmark]] of squamous cell carcinoma of the lung is [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]] may be suggestive of squamous cell carcinoma of the lung. [[Symptom|Symptoms]] related with squamous cell carcinoma of the lung will vary depending on the size and location of the [[tumor]]. Common [[Symptom|symptoms]] of squamous cell carcinoma of the lung may also include [[shortness of breath]], [[fatigue]], and [[chest pain]]. Less common [[Symptom|symptoms]] of squamous cell carcinoma of the lung include [[bone pain]], [[fatigue]], [[dizziness]], [[dysphagia]], and [[numbness]] in extremities.


==History==
==History and Symptoms==


*Obtaining the history is an important aspect of making a diagnosis of squamous cell carcinoma of the lung. It provides insight into natural evolution of the disease. Complete history will help determine the likelihood of metastases, and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref>  
=== History ===
 
*Obtaining the history is an important aspect of making a [[diagnosis]] of squamous cell carcinoma of the lung.  
*It provides insight into natural evolution of the [[disease]].  
*Complete history will help determine the likelihood of [[Metastasis|metastases]], and the association with other conditions.  
*Specific [[Symptom|symptoms]] description such as duration, onset, and progression are important for making the [[diagnosis]].  
*Specific areas of focus when obtaining the history are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref>
    
    
*Family history of cancer
**Family history of cancer
*Personal history of cancer  
**Personal history of cancer
:*[[Colorectal cancer]]
 
:*[[Bladder cancer]]  
:**[[Colorectal cancer]]
:*[[Breast cancer]]
:**[[Bladder cancer]]
:*[[Prostate cancer]]
:**[[Breast cancer]]
:**[[Prostate cancer]]
 
*Positive history of active/passive smoking
*Positive history of active/passive smoking
:*Number of cigarettes/year  
:*Number of cigarettes/year  
Line 22: Line 30:
:*Number of years/months of [[smoking cessation]]  
:*Number of years/months of [[smoking cessation]]  
*Associated conditions, such as:  
*Associated conditions, such as:  
:*Chronic obstructive pulmonary disease
:*[[Chronic obstructive pulmonary disease]]
:*Emphysema
:*[[Emphysema]]
 
===Common Symptoms===


==Common Symptoms==
*The majority of non-small cell lung cancers are [[asymptomatic]] and are usually found incidentally.
*The majority of non-small cell lung cancers are [[asymptomatic]] and are usually found incidentally.
*Symptoms and signs may result from the location of the primary local invasion or compression of adjacent thoracic structures, distant metastases, or paraneoplastic phenomena.
*Symptoms and signs may result from the location of the primary local invasion or compression of adjacent thoracic structures, distant metastases, or paraneoplastic phenomena.
*The hallmark of squamous cell carcinoma of the lung is chronic cough, weight loss, and hemoptysis.
*The hallmark of squamous cell carcinoma of the lung is chronic cough, weight loss, and hemoptysis.
*Other symptoms that suggest non small cell lung cancer, include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
*Other symptoms that suggest non small cell lung cancer, include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
**[[Dyspnea]]  
**[[Dyspnea]]
**[[Hemoptysis]]  
**[[Hemoptysis]]
**Chronic [[coughing]]
**Chronic [[coughing]]
**[[Weight loss]]
**[[Weight loss]]
Line 37: Line 46:
**[[Chest pain]]
**[[Chest pain]]
**[[Abdominal pain]]
**[[Abdominal pain]]
**[[Cachexia]]  
**[[Cachexia]]
**Loss of [[appetite]]
**Loss of [[appetite]]
**[[Dysphonia]]
**[[Dysphonia]]
**[[Malaise]]
**[[Malaise]]


==Less Common Symptoms==
===Less Common Symptoms===
 
*Other less common symptoms of non-small cell lung cancer include:<ref>https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf</ref>


*Other less common symptoms of non-small cell lung cancer, include:<ref>https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf</ref>
'''Late Symptoms'''
'''Late Symptoms'''
**[[Bone pain]]
**[[Bone pain]]
**[[Dysphagia]]
**[[Dysphagia]]
**[[Fatigue]]
**[[Fatigue]]
**Numbness in extremities
**[[Numbness]] in extremities
**[[Dizziness]]
**[[Dizziness]]
**[[Seizure]]
**[[Seizure]]

Latest revision as of 17:56, 18 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The hallmark of squamous cell carcinoma of the lung is chronic cough, weight loss, and hemoptysis. A positive history of smoking may be suggestive of squamous cell carcinoma of the lung. Symptoms related with squamous cell carcinoma of the lung will vary depending on the size and location of the tumor. Common symptoms of squamous cell carcinoma of the lung may also include shortness of breath, fatigue, and chest pain. Less common symptoms of squamous cell carcinoma of the lung include bone pain, fatigue, dizziness, dysphagia, and numbness in extremities.

History and Symptoms

History

  • Obtaining the history is an important aspect of making a diagnosis of squamous cell carcinoma of the lung.
  • It provides insight into natural evolution of the disease.
  • Complete history will help determine the likelihood of metastases, and the association with other conditions.
  • Specific symptoms description such as duration, onset, and progression are important for making the diagnosis.
  • Specific areas of focus when obtaining the history are outlined below:[1]
    • Family history of cancer
    • Personal history of cancer
  • Positive history of active/passive smoking
  • Number of cigarettes/year
  • Number of years/months of active smoking
  • Number of years/months of smoking cessation
  • Associated conditions, such as:

Common Symptoms

Less Common Symptoms

  • Other less common symptoms of non-small cell lung cancer include:[5]

Late Symptoms

References

  1. Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
  2. Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  3. Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015
  4. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I non-small cell lung cancer: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
  5. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf