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__NOTOC__
[[Syncope]] is classified into three types:
{| class="wikitable"
* [[Cardiac]]
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* [[Neurogenic]]
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* [[Vasovagal syncope|vasovagal]]
| align="center" style="background:#4479BA; color: #FFFFFF;" |'''Type of paraneoplastic syndrome'''
| align="center" style="background:#4479BA; color: #FFFFFF;" |'''Subtype'''
| align="center" style="background:#4479BA; color: #FFFFFF;" |'''Associated Cancers'''
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| rowspan="5"  align="center" style="background:#f0f0f0;" |[[Endocrine]]
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* [[Hypercalcemia]]
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* [[Breast cancer]] and [[lung cancer]] (typically [[Squamous cell carcinoma|squamous cell]]) due to the production of [[Parathyroid hormone-related protein|PTHrP]] ([[Parathyroid hormone]]-related [[protein]])[[multiple myeloma]], [[renal cell carcinoma]], [[ovarian cancer]], [[endometrial cancer]], and [[lymphoma]]
 
*
|-
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* [[Syndrome of inappropriate antidiuretic hormone|SIADH]]
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* [[Small cell lung cancer|Small-cell lung cancer]], [[mesothelioma]], [[breast]], [[prostate]], [[adrenal]], [[urethral]], [[thymoma]], [[lymphoma]], GI, CNS, and [[Ewing sarcoma]]
 
*
|-
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* [[Ectopic]] [[ACTH]] [[secretion]]
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* [[Small cell lung cancer|Small-cell lung cancer]], [[carcinoid tumor]], [[thymoma]] and other [[Cancer|cancers]]
|-
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* [[Tumor induced osteomalacia]]<ref name="FlorenzanoGafni2017">{{cite journal|last1=Florenzano|first1=Pablo|last2=Gafni|first2=Rachel I.|last3=Collins|first3=Michael T.|title=Tumor-induced osteomalacia|journal=Bone Reports|volume=7|year=2017|pages=90–97|issn=23521872|doi=10.1016/j.bonr.2017.09.002}}</ref>
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* [[Metastatic]] [[breast cancer]]
 
*
|-
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* [[Hypoglycemia]]
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* [[Gastrointestinal tract|GI]] cancers, [[mesothelioma]], [[lung]], and [[sarcomas]]
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| rowspan="6"  align="center" style="background:#f0f0f0;" |[[Mucocutaneous|Musculocutaneous]]
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* [[Dermatomyositis]]<ref name="ThiersSahn2009">{{cite journal|last1=Thiers|first1=B. H.|last2=Sahn|first2=R. E.|last3=Callen|first3=J. P.|title=Cutaneous Manifestations of Internal Malignancy|journal=CA: A Cancer Journal for Clinicians|volume=59|issue=2|year=2009|pages=73–98|issn=0007-9235|doi=10.3322/caac.20005}}</ref>
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* [[Breast cancer|Breast]], [[Ovarian cancer|ovarian]], [[Lung cancer|lung]], and [[prostate cancer]]
 
*
|-
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* [[Leser-Trelat sign|Leser-Trélat sign]]
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* Gastrointestinal [[adenocarcinomas]] ([[Gastric adenocarcinoma|gastric]], [[Colon adenocarcinoma|colon]], rectal), [[breast cancer]], [[lymphoproliferative disorders]]/[[lymphoma]], and [[melanoma]].
 
*
|-
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* [[Acanthosis nigricans]]
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* [[Gastric adenocarcinoma]], [[endometrial cancer]].
 
*
|-
|
* [[Necrolytic migratory erythema]]<ref name="TremblayMarcil2017">{{cite journal|last1=Tremblay|first1=Catherine|last2=Marcil|first2=Isabelle|title=Necrolytic Migratory Erythema: A Forgotten Paraneoplastic Condition|journal=Journal of Cutaneous Medicine and Surgery|volume=21|issue=6|year=2017|pages=559–561|issn=1203-4754|doi=10.1177/1203475417719051}}</ref>
|
* [[Glucagonoma]]
 
*
|-
|
* [[Sweet's syndrome]]<ref name="CohenKurzrock1987">{{cite journal|last1=Cohen|first1=Philip R.|last2=Kurzrock|first2=Razelle|title=Sweet's syndrome and malignancy|journal=The American Journal of Medicine|volume=82|issue=6|year=1987|pages=1220–1226|issn=00029343|doi=10.1016/0002-9343(87)90229-4}}</ref>
|
* [[Acute myeloid leukemia|Acute myelogenous leukemia]], [[Myeloproliferative disease|myeloproliferative disorders]], [[lymphoproliferative disorders]], [[myelodysplastic syndrome]], and [[carcinoma]]
 
*
|-
|
* [[Pyoderma gangrenosum]]
|
* AAAAAA
 
*
|-
|+
|-
| rowspan="11"  align="center" style="background:#f0f0f0;" |[[Neurological]]
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* [[Paraneoplastic cerebellar degeneration]]<ref name="AbdulazizYu2018">{{cite journal|last1=Abdulaziz|first1=Ammar Taha Abdullah|last2=Yu|first2=Xiao Qing|last3=Zhang|first3=Le|last4=Jiang|first4=Xin Yue|last5=Zhou|first5=Dong|last6=Li|first6=Jin Mei|title=Paraneoplastic cerebellar degeneration associated with cerebellar hypermetabolism|journal=Medicine|volume=97|issue=24|year=2018|pages=e10717|issn=0025-7974|doi=10.1097/MD.0000000000010717}}</ref>
 
|
* [[Breast cancer|Breast]] and [[gynecological malignancies]]
 
*
|-
|
* [[Encephalomyelitis]]<ref name="Graus2001">{{cite journal|last1=Graus|first1=F.|title=Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients|journal=Brain|volume=124|issue=6|year=2001|pages=1138–1148|issn=14602156|doi=10.1093/brain/124.6.1138}}</ref>
 
|
* [[Bronchial cancer]] (typically [[small cell lung carcinoma]])
*
|-
|
* [[Limbic encephalitis]]<ref name="ShenXu2018">{{cite journal|last1=Shen|first1=Kaini|last2=Xu|first2=Yan|last3=Guan|first3=Hongzhi|last4=Zhong|first4=Wei|last5=Chen|first5=Minjiang|last6=Zhao|first6=Jing|last7=Li|first7=Longyun|last8=Wang|first8=Mengzhao|title=Paraneoplastic limbic encephalitis associated with lung cancer|journal=Scientific Reports|volume=8|issue=1|year=2018|issn=2045-2322|doi=10.1038/s41598-018-25294-y}}</ref>
|
* [[Lung cancer]]
*
|-
|
* [[Encephalitis|Brainstem encephalitis]]
|
* EEEEEEE
 
*
|-
|
* [[Opsoclonus]] (involving eye movement)
|
* FFFFFFFF
 
*
|-
|
* [[Encephalitis]]
|
* [[Teratoma]]
|-
|
* [[Polymyositis]]
|
* GGGGGGGGGGGGGG
|-
|
* [[Autonomic neuropathy]]
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* HHHHHHHHHHH
|-
|
* [[Lambert-Eaton myasthenic syndrome]] ([[LEMS]])
|
* [[Small cell lung cancer|Small-cell lung cancer]]
|-
|
* [[Myasthenia gravis]]
|
* IIIIIIIIIIIIIIIIII
|-
|
* Subacute (peripheral) [[sensory neuropathy]]
|
* JJJJJJJJJJJJJJJ
|-
| rowspan="4"  align="center" style="background:#f0f0f0;" |[[Hematological]]<ref name="PelosofGerber2010">{{cite journal|last1=Pelosof|first1=Lorraine C.|last2=Gerber|first2=David E.|title=Paraneoplastic Syndromes: An Approach to Diagnosis and Treatment|journal=Mayo Clinic Proceedings|volume=85|issue=9|year=2010|pages=838–854|issn=00256196|doi=10.4065/mcp.2010.0099}}</ref>
|
* [[Granulocytosis]]<ref name="AscensaoOken1987">{{cite journal|last1=Ascensao|first1=Joad L.|last2=Oken|first2=Martin M.|last3=Ewing|first3=Stephen L.|last4=Goldberg|first4=Robert J.|last5=Kaplan|first5=Manuel E.|title=Leukocytosis and large cell lung cancer. A frequent association|journal=Cancer|volume=60|issue=4|year=1987|pages=903–905|issn=0008-543X|doi=10.1002/1097-0142(19870815)60:4<903::AID-CNCR2820600431>3.0.CO;2-6}}</ref><ref name="AhnPark2005">{{cite journal|last1=Ahn|first1=Heui June|last2=Park|first2=Yeon Hee|last3=Chang|first3=Yoon Hwan|last4=Park|first4=Sun Hoo|last5=Kim|first5=Min-Suk|last6=Ryoo|first6=Baek Yeol|last7=Yang|first7=Sung Hyun|title=A Case of Uterine Cervical Cancer Presenting with Granulocytosis|journal=The Korean Journal of Internal Medicine|volume=20|issue=3|year=2005|pages=247|issn=1226-3303|doi=10.3904/kjim.2005.20.3.247}}</ref>
|
* [[Lung cancer]] (particularly [[large cell lung cancer]]), [[Gastrointestinal cancer|gastrointestinal]], [[Brain cancer|brain]], [[Breast cancer|breast]], [[Renal cancer|renal]], and [[gynecologic cancers]]
|-
|
* [[Thrombocytosis]]<ref name="StoneNick2012">{{cite journal|last1=Stone|first1=Rebecca L.|last2=Nick|first2=Alpa M.|last3=McNeish|first3=Iain A.|last4=Balkwill|first4=Frances|last5=Han|first5=Hee Dong|last6=Bottsford-Miller|first6=Justin|last7=Rupaimoole|first7=Rajesha|last8=Armaiz-Pena|first8=Guillermo N.|last9=Pecot|first9=Chad V.|last10=Coward|first10=Jermaine|last11=Deavers|first11=Michael T.|last12=Vasquez|first12=Hernan G.|last13=Urbauer|first13=Diana|last14=Landen|first14=Charles N.|last15=Hu|first15=Wei|last16=Gershenson|first16=Hannah|last17=Matsuo|first17=Koji|last18=Shahzad|first18=Mian M.K.|last19=King|first19=Erin R.|last20=Tekedereli|first20=Ibrahim|last21=Ozpolat|first21=Bulent|last22=Ahn|first22=Edward H.|last23=Bond|first23=Virginia K.|last24=Wang|first24=Rui|last25=Drew|first25=Angela F.|last26=Gushiken|first26=Francisca|last27=Lamkin|first27=Donald|last28=Collins|first28=Katherine|last29=DeGeest|first29=Koen|last30=Lutgendorf|first30=Susan K.|last31=Chiu|first31=Wah|last32=Lopez-Berestein|first32=Gabriel|last33=Afshar-Kharghan|first33=Vahid|last34=Sood|first34=Anil K.|title=Paraneoplastic Thrombocytosis in Ovarian Cancer|journal=New England Journal of Medicine|volume=366|issue=7|year=2012|pages=610–618|issn=0028-4793|doi=10.1056/NEJMoa1110352}}</ref>
|
* [[Ovarian cancer]]
|-
|
* [[Pure red cell aplasia]]<ref name="RosuCohen2011">{{cite journal|last1=Rosu|first1=Cristian|last2=Cohen|first2=Sandra|last3=Meunier|first3=Caroline|last4=Ouellette|first4=Denise|last5=Beauchamp|first5=Gilles|last6=Rakovich|first6=George|title=Pure red cell aplasia and associated thymoma|journal=Clinics and Practice|volume=1|issue=1|year=2011|pages=1|issn=2039-7283|doi=10.4081/cp.2011.e1}}</ref>
|
* [[Thymoma]], [[lymphoma]], [[leukemia]]
|-
|
* [[Eosinophilia]]<ref name="PelosofGerber2010">{{cite journal|last1=Pelosof|first1=Lorraine C.|last2=Gerber|first2=David E.|title=Paraneoplastic Syndromes: An Approach to Diagnosis and Treatment|journal=Mayo Clinic Proceedings|volume=85|issue=9|year=2010|pages=838–854|issn=00256196|doi=10.4065/mcp.2010.0099}}</ref>
|
* [[Lymphomas]], [[leukemias]], [[lung]], [[Gastrointestinal tumor|gastrointestinal]], and [[Genital cancer|gynecologic]] [[tumors]]
|-
| align="center" style="background:#f0f0f0;" |Others
|
* [[Membranous glomerulonephritis]]<ref name="LeeaphornKue-A-Pai2014">{{cite journal|last1=Leeaphorn|first1=Napat|last2=Kue-A-Pai|first2=Pogsathorn|last3=Thamcharoen|first3=Natanong|last4=Ungprasert|first4=Patompong|last5=Stokes|first5=Michael B.|last6=Knight|first6=Eric L.|title=Prevalence of Cancer in Membranous Nephropathy: A Systematic Review and Meta-Analysis of Observational Studies|journal=American Journal of Nephrology|volume=40|issue=1|year=2014|pages=29–35|issn=1421-9670|doi=10.1159/000364782}}</ref>
|
* [[Lung cancer]], [[prostate cancer]], and [[Hematologic malignancy|hematologic malignancies]]
|-
|}
 
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Latest revision as of 00:32, 12 August 2021

Syncope is classified into three types: