SLC7A1
| Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | |||||||||||
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| Identifiers | |||||||||||
| Symbols | SLC7A1 ; ATRC1; CAT-1; ERR; HCAT1; REC1L | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 20658 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SLC7A1 206566 at tn.png | |||||||||||
| File:PBB GE SLC7A1 212290 at tn.png | |||||||||||
| File:PBB GE SLC7A1 212292 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1, also known as SLC7A1, is a human gene.[1]
See also
References
Further reading
- Albritton LM, Bowcock AM, Eddy RL; et al. (1992). "The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14". Genomics. 12 (3): 430–4. PMID 1348489.
- Yoshimoto T, Yoshimoto E, Meruelo D (1991). "Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor". Virology. 185 (1): 10–7. PMID 1718082.
- Kamath SG, Furesz TC, Way BA, Smith CH (1999). "Identification of three cationic amino acid transporters in placental trophoblast: cloning, expression, and characterization of hCAT-1". J. Membr. Biol. 171 (1): 55–62. PMID 10485994.
- Hammermann R, Brunn G, Racké K (2002). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids. 21 (2): 211–9. PMID 11665818.
- Cariappa R, Heath-Monnig E, Furesz TC; et al. (2002). "Stable polarized expression of hCAT-1 in an epithelial cell line". J. Membr. Biol. 186 (1): 23–30. doi:10.1007/s00232-001-0133-y. PMID 11891586.
- Furesz TC, Heath-Monnig E, Kamath SG, Smith CH (2003). "Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes". J. Membr. Biol. 189 (1): 27–33. doi:10.1007/s00232-002-1001-0. PMID 12202949.
- Kizhatil K, Albritton LM (2002). "System y+ localizes to different membrane subdomains in the basolateral plasma membrane of epithelial cells". Am. J. Physiol., Cell Physiol. 283 (6): C1784–94. doi:10.1152/ajpcell.00061.2002. PMID 12388095.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Schnorr O, Suschek CV, Kolb-Bachofen V (2003). "The importance of cationic amino acid transporter expression in human skin". J. Invest. Dermatol. 120 (6): 1016–22. doi:10.1046/j.1523-1747.2003.12139.x. PMID 12787129.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Dunham A, Matthews LH, Burton J; et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.
- González M, Flores C, Pearson JD; et al. (2005). "Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells". Pflugers Arch. 448 (4): 383–94. doi:10.1007/s00424-004-1261-x. PMID 15064952.
- Schwartz IF, Iaina A, Benedict Y; et al. (2004). "Augmented arginine uptake, through modulation of cationic amino acid transporter-1, increases GFR in diabetic rats". Kidney Int. 65 (4): 1311–9. doi:10.1111/j.1523-1755.2004.00508.x. PMID 15086470.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rotmann A, Strand D, Martiné U, Closs EI (2005). "Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity". J. Biol. Chem. 279 (52): 54185–92. doi:10.1074/jbc.M409556200. PMID 15491978.
- Cui Z, Tuladhar R, Hart SL; et al. (2005). "Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells". Nitric Oxide. 12 (1): 21–30. doi:10.1016/j.niox.2004.11.001. PMID 15631944.
- Yang Z, Venardos K, Jones E; et al. (2007). "Identification of a novel polymorphism in the 3'UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction". Circulation. 115 (10): 1269–74. doi:10.1161/CIRCULATIONAHA.106.665836. PMID 17325243.
- Kaneko S, Okuda-Ashitaka E, Ando A; et al. (2007). "Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells". Am. J. Physiol., Cell Physiol. 293 (2): C729–37. doi:10.1152/ajpcell.00018.2007. PMID 17494634.