SLC39A2: Difference between revisions

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{{Infobox_gene}}
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'''Zinc transporter ZIP2''' is a [[protein]] that in humans is encoded by the ''SLC39A2'' [[gene]].<ref name="pmid10681536">{{cite journal | vauthors = Gaither LA, Eide DJ | title = Functional expression of the human hZIP2 zinc transporter | journal = J Biol Chem | volume = 275 | issue = 8 | pages = 5560–4 |date=Mar 2000 | pmid = 10681536 | pmc =  | doi =10.1074/jbc.275.8.5560 }}</ref><ref name="pmid7751801">{{cite journal | author = Yamaguchi S | title = [Subtraction cloning of growth arrest inducible genes in normal human epithelial cells] | journal = Kokubyo Gakkai Zasshi | volume = 62 | issue = 1 | pages = 78–93 |date=Jun 1995 | pmid = 7751801 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC39A2 solute carrier family 39 (zinc transporter), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29986| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Solute carrier family 39 (zinc transporter), member 2
| HGNCid = 17127
| Symbol = SLC39A2
| AltSymbols =; MGC119190; ZIP2
| OMIM =
| ECnumber =
| Homologene = 40957
| MGIid = 2684326
  | GeneAtlas_image1 = PBB_GE_SLC39A2_220413_at_tn.png
  | Function = {{GNF_GO|id=GO:0005385 |text = zinc ion transmembrane transporter activity}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046873 |text = metal ion transmembrane transporter activity}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
| Process = {{GNF_GO|id=GO:0006811 |text = ion transport}} {{GNF_GO|id=GO:0006829 |text = zinc ion transport}} {{GNF_GO|id=GO:0030001 |text = metal ion transport}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 29986
    | Hs_Ensembl = ENSG00000165794
    | Hs_RefseqProtein = NP_055394
    | Hs_RefseqmRNA = NM_014579
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 20537289
    | Hs_GenLoc_end = 20539870
    | Hs_Uniprot = Q9NP94
    | Mm_EntrezGene = 214922
    | Mm_Ensembl = ENSMUSG00000072572
    | Mm_RefseqmRNA = XM_972857
    | Mm_RefseqProtein = XP_977951
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 14
    | Mm_GenLoc_start = 50815610
    | Mm_GenLoc_end = 50818696
    | Mm_Uniprot = 
  }}
}}
'''Solute carrier family 39 (zinc transporter), member 2''', also known as '''SLC39A2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC39A2 solute carrier family 39 (zinc transporter), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29986| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal | author=Yamaguchi S |title=[Subtraction cloning of growth arrest inducible genes in normal human epithelial cells] |journal=Kokubyo Gakkai Zasshi |volume=62 |issue= 1 |pages= 78-93 |year= 1995 |pmid= 7751801 |doi=  }}
*{{cite journal   |vauthors=Gong J, Xu J, Bezanilla M, etal |title=Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2. |journal=Science |volume=285 |issue= 5433 |pages= 1565–9 |year= 1999 |pmid= 10477520 |doi=10.1126/science.285.5433.1565 }}
*{{cite journal  | author=Gong J, Xu J, Bezanilla M, ''et al.'' |title=Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2. |journal=Science |volume=285 |issue= 5433 |pages= 1565-9 |year= 1999 |pmid= 10477520 |doi= }}
*{{cite journal  | vauthors=Croci C, Brändstatter JH, Enz R |title=ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2. |journal=J. Biol. Chem. |volume=278 |issue= 8 |pages= 6128–35 |year= 2003 |pmid= 12431995 |doi= 10.1074/jbc.M205162200 }}
*{{cite journal  | author=Gaither LA, Eide DJ |title=Functional expression of the human hZIP2 zinc transporter. |journal=J. Biol. Chem. |volume=275 |issue= 8 |pages= 5560-4 |year= 2000 |pmid= 10681536 |doi= }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Croci C, Brändstatter JH, Enz R |title=ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2. |journal=J. Biol. Chem. |volume=278 |issue= 8 |pages= 6128-35 |year= 2003 |pmid= 12431995 |doi= 10.1074/jbc.M205162200 }}
*{{cite journal   |vauthors=Dufner-Beattie J, Langmade SJ, Wang F, etal |title=Structure, function, and regulation of a subfamily of mouse zinc transporter genes. |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 50142–50 |year= 2004 |pmid= 14525987 |doi= 10.1074/jbc.M304163200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Suzuki Y, Yamashita R, Shirota M, etal |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 | pmc=515316 }}
*{{cite journal | author=Dufner-Beattie J, Langmade SJ, Wang F, ''et al.'' |title=Structure, function, and regulation of a subfamily of mouse zinc transporter genes. |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 50142-50 |year= 2004 |pmid= 14525987 |doi= 10.1074/jbc.M304163200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Suzuki Y, Yamashita R, Shirota M, ''et al.'' |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Desouki MM, Geradts J, Milon B, etal |title=hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. |journal=Mol. Cancer |volume=6 |issue=  |pages= 37 |year= 2007 |pmid= 17550612 |doi= 10.1186/1476-4598-6-37 | pmc=1892035 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal | author=Desouki MM, Geradts J, Milon B, ''et al.'' |title=hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. |journal=Mol. Cancer |volume=6 |issue=  |pages= 37 |year= 2007 |pmid= 17550612 |doi= 10.1186/1476-4598-6-37 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
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[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
{{WikiDoc Sources}}
 
 
{{membrane-protein-stub}}

Latest revision as of 06:33, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc transporter ZIP2 is a protein that in humans is encoded by the SLC39A2 gene.[1][2][3]


See also

References

  1. ↑ Gaither LA, Eide DJ (Mar 2000). "Functional expression of the human hZIP2 zinc transporter". J Biol Chem. 275 (8): 5560–4. doi:10.1074/jbc.275.8.5560. PMID 10681536.
  2. ↑ Yamaguchi S (Jun 1995). "[Subtraction cloning of growth arrest inducible genes in normal human epithelial cells]". Kokubyo Gakkai Zasshi. 62 (1): 78–93. PMID 7751801.
  3. ↑ "Entrez Gene: SLC39A2 solute carrier family 39 (zinc transporter), member 2".

Further reading


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