SLC27A3: Difference between revisions

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{{Infobox_gene}}
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'''Long-chain fatty acid transport protein 3''' is a [[protein]] that in humans is encoded by the ''SLC27A3'' [[gene]].<ref name="pmid9671728">{{cite journal | vauthors = Hirsch D, Stahl A, Lodish HF | title = A family of fatty acid transporters conserved from mycobacterium to man | journal = Proc Natl Acad Sci U S A | volume = 95 | issue = 15 | pages = 8625–9 |date=Aug 1998 | pmid = 9671728 | pmc = 21126 | doi =10.1073/pnas.95.15.8625 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC27A3 solute carrier family 27 (fatty acid transporter), member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11000| accessdate = }}</ref>
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In melanocytic cells SLC27A3 gene expression may be regulated by [[Microphthalmia-associated transcription factor|MITF]].<ref name="pmid19067971">{{cite journal  |vauthors=Hoek KS, Schlegel NC, Eichhoff OM, etal | title = Novel MITF targets identified using a two-step DNA microarray strategy | journal = Pigment Cell Melanoma Res. | volume = 21 | issue = 6 | pages = 665–76 | year = 2008 | pmid = 19067971 | doi = 10.1111/j.1755-148X.2008.00505.x }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = Solute carrier family 27 (fatty acid transporter), member 3
| HGNCid = 10997
| Symbol = SLC27A3
| AltSymbols =; ACSVL3; FATP3; MGC4365; VLCS-3
| OMIM = 604193
| ECnumber =
| Homologene = 11529
| MGIid = 1347358
| GeneAtlas_image1 = PBB_GE_SLC27A3_222217_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}}{{GNF_GO|id=GO:0004321 |text = fatty-acyl-CoA synthase activity}}{{GNF_GO|id=GO:0016874 |text = ligase activity}}
| Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006629 |text = lipid metabolic process}} {{GNF_GO|id=GO:0006631 |text = fatty acid metabolic process}} {{GNF_GO|id=GO:0008152 |text = metabolic process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 11000
    | Hs_Ensembl = ENSG00000143554
    | Hs_RefseqProtein = NP_077306
    | Hs_RefseqmRNA = NM_024330
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 152013454
    | Hs_GenLoc_end = 152019257
    | Hs_Uniprot = Q5K4L6
    | Mm_EntrezGene = 26568
    | Mm_Ensembl = ENSMUSG00000027932
    | Mm_RefseqmRNA = NM_011988
    | Mm_RefseqProtein = NP_036118
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 90471167
    | Mm_GenLoc_end = 90475865
    | Mm_Uniprot = Q2UZQ7
  }}
}}
'''Solute carrier family 27 (fatty acid transporter), member 3''', also known as '''SLC27A3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC27A3 solute carrier family 27 (fatty acid transporter), member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11000| accessdate = }}</ref>


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==See also==
==See also==
* {{MeshName|SLC27A3+protein,+human}}
* {{MeshName|SLC27A3+protein,+human}}
* [[Solute carrier family]]


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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| citations =  
| citations =  
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Pei Z, Fraisl P, Berger J, ''et al.'' |title=Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells. |journal=J. Biol. Chem. |volume=279 |issue= 52 |pages= 54454-62 |year= 2005 |pmid= 15469937 |doi= 10.1074/jbc.M410091200 }}
*{{cite journal   |vauthors=Pei Z, Fraisl P, Berger J, etal |title=Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells |journal=J. Biol. Chem. |volume=279 |issue= 52 |pages= 54454–62 |year= 2005 |pmid= 15469937 |doi= 10.1074/jbc.M410091200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal | author=Hirsch D, Stahl A, Lodish HF |title=A family of fatty acid transporters conserved from mycobacterium to man. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 15 |pages= 8625-9 |year= 1998 |pmid= 9671728 |doi=  }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{NLM content}}
{{NLM content}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
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[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
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{{membrane-protein-stub}}

Latest revision as of 06:30, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene.[1][2]

In melanocytic cells SLC27A3 gene expression may be regulated by MITF.[3]


See also

References

  1. ↑ Hirsch D, Stahl A, Lodish HF (Aug 1998). "A family of fatty acid transporters conserved from mycobacterium to man". Proc Natl Acad Sci U S A. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.
  2. ↑ "Entrez Gene: SLC27A3 solute carrier family 27 (fatty acid transporter), member 3".
  3. ↑ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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