SLC1A1
| Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SLC1A1 ; EAAC1; EAAT3 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 20881 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SLC1A1 213664 at tn.png | |||||||||||
| File:PBB GE SLC1A1 206396 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, also known as SLC1A1, is a human gene.[1]
See also
References
Further reading
- Nieoullon A, Canolle B, Masmejean F; et al. (2006). "The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse?". J. Neurochem. 98 (4): 1007–18. doi:10.1111/j.1471-4159.2006.03978.x. PMID 16800850.
- Arriza JL, Fairman WA, Wadiche JI; et al. (1994). "Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex". J. Neurosci. 14 (9): 5559–69. PMID 7521911.
- Shashidharan P, Huntley GW, Meyer T; et al. (1995). "Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brain". Brain Res. 662 (1–2): 245–50. PMID 7859077.
- Kanai Y, Stelzner M, Nussberger S; et al. (1994). "The neuronal and epithelial human high affinity glutamate transporter. Insights into structure and mechanism of transport". J. Biol. Chem. 269 (32): 20599–606. PMID 7914198.
- Smith CP, Weremowicz S, Kanai Y; et al. (1994). "Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: potential role in dicarboxylic aminoaciduria and neurodegenerative disorders". Genomics. 20 (2): 335–6. doi:10.1006/geno.1994.1183. PMID 8020993.
- Zerangue N, Kavanaugh MP (1997). "Interaction of L-cysteine with a human excitatory amino acid transporter". J. Physiol. (Lond.). 493 ( Pt 2): 419–23. PMID 8782106.
- Bar-Peled O, Ben-Hur H, Biegon A; et al. (1997). "Distribution of glutamate transporter subtypes during human brain development". J. Neurochem. 69 (6): 2571–80. PMID 9375691.
- He Y, Janssen WG, Rothstein JD, Morrison JH (2000). "Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus". J. Comp. Neurol. 418 (3): 255–69. PMID 10701825.
- Lin CI, Orlov I, Ruggiero AM; et al. (2001). "Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18". Nature. 410 (6824): 84–8. doi:10.1038/35065084. PMID 11242046.
- Veenstra-VanderWeele J, Kim SJ, Gonen D; et al. (2001). "Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder". Mol. Psychiatry. 6 (2): 160–7. doi:10.1038/sj.mp.4000806. PMID 11317217.
- Borre L, Kavanaugh MP, Kanner BI (2002). "Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter". J. Biol. Chem. 277 (16): 13501–7. doi:10.1074/jbc.M110861200. PMID 11823462.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- González MI, Bannerman PG, Robinson MB (2003). "Phorbol myristate acetate-dependent interaction of protein kinase Calpha and the neuronal glutamate transporter EAAC1". J. Neurosci. 23 (13): 5589–93. PMID 12843260.
- Noorlander CW, de Graan PN, Nikkels PG; et al. (2004). "Distribution of glutamate transporters in the human placenta". Placenta. 25 (6): 489–95. doi:10.1016/j.placenta.2003.10.018. PMID 15135231.
- Humphray SJ, Oliver K, Hunt AR; et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Koch HP, Larsson HP (2005). "Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters". J. Neurosci. 25 (7): 1730–6. doi:10.1523/JNEUROSCI.4138-04.2005. PMID 15716409.
- Vallejo-Illarramendi A, Domercq M, Pérez-Cerdá F; et al. (2006). "Increased expression and function of glutamate transporters in multiple sclerosis". Neurobiol. Dis. 21 (1): 154–64. doi:10.1016/j.nbd.2005.06.017. PMID 16061389.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Rainesalo S, Keränen T, Saransaari P, Honkaniemi J (2006). "GABA and glutamate transporters are expressed in human platelets". Brain Res. Mol. Brain Res. 141 (2): 161–5. doi:10.1016/j.molbrainres.2005.08.013. PMID 16198020.
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