Polycystic kidney disease natural history: Difference between revisions
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==Overview== | ==Overview== | ||
Polycystic kidney disease is a multiorgan and progressive disorder characterized by formation of [[cyst]]s in [[kidney]] and other organs like [[pancreas]], [[liver]] and [[spleen]]. | |||
==Natural History== | ==Natural History== | ||
*Symptoms of polycystic kidney disease begin in the third or fourth decade of life. However, the renal [[cyst]]s can be detected as early as childhood or in utero. | |||
*The [[cyst]]s gradually grow in size replacing most of the renal tissue with [[cyst]]s, compromising its normal function. | |||
*[[Creatinine]] begins to built up and eventually the patient goes into [[end stage renal disease]]. | |||
==Complications== | ==Complications== | ||
Revision as of 16:19, 20 August 2012
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Differentiating Polycystic kidney disease from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
Polycystic kidney disease is a multiorgan and progressive disorder characterized by formation of cysts in kidney and other organs like pancreas, liver and spleen.
Natural History
- Symptoms of polycystic kidney disease begin in the third or fourth decade of life. However, the renal cysts can be detected as early as childhood or in utero.
- The cysts gradually grow in size replacing most of the renal tissue with cysts, compromising its normal function.
- Creatinine begins to built up and eventually the patient goes into end stage renal disease.
Complications
- Anemia
- Rupture of cysts
- Infection of liver cysts
- Chronic renal failure
- Hypertension
- Nephrolithiasis
- Liver failure
- Urinary tract infection
Prognosis
The disease gets worse slowly. Eventually it leads to end-stage chronic renal failure. It is also associated with liver disease, including infection of liver cysts. Medical treatment may relieve symptoms for many years. People with PKD who do not have other diseases may be good candidates for a kidney transplant.