Polycystic kidney disease epidemiology and demographics: Difference between revisions

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==Overview==
Polycystic kidney disease is one of the most common genetic cause of [[chronic renal failure]] in adults.


==Epidemiology==
==Epidemiology==
 
*Polycystic kidney disease is the most common life-threatening genetic disease, affecting approximately 7 million people worldwide. Autosomal dominant polycystic kidney disease affects up to 1 in 1000 people, while the autosomal recessive type is estimated to occur in approximately 1 in 20,000 people.<ref name="Dalgaard_1957">{{cite journal |author=DALGAARD OZ |title=Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families |journal=Acta Med. Scand. Suppl. |volume=328 |issue= |pages=1-255 |year=1957 |pmid=13469269 |doi=}}</ref><ref name="Zerres_1998">{{cite journal |author=Zerres K, Mücher G, Becker J, ''et al'' |title=Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology |journal=Am. J. Med. Genet. |volume=76 |issue=2 |pages=137-44 |year=1998 |pmid=9511976 |doi=}}</ref>
Polycystic kidney disease is the most common life-threatening genetic disease, affecting approximately 7 million people worldwide. Autosomal dominant polycystic kidney disease affects up to 1 in 1000 people, while the autosomal recessive type is estimated to occur in approximately 1 in 20,000 people.<ref name="Dalgaard_1957">{{cite journal |author=DALGAARD OZ |title=Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families |journal=Acta Med. Scand. Suppl. |volume=328 |issue= |pages=1-255 |year=1957 |pmid=13469269 |doi=}}</ref><ref name="Zerres_1998">{{cite journal |author=Zerres K, Mücher G, Becker J, ''et al'' |title=Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology |journal=Am. J. Med. Genet. |volume=76 |issue=2 |pages=137-44 |year=1998 |pmid=9511976 |doi=}}</ref>
*It affects men and women equally


==References==
==References==

Revision as of 16:06, 20 August 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Cafer Zorkun, M.D., Ph.D. [2] Aarti Narayan, M.B.B.S [3]

Overview

Polycystic kidney disease is one of the most common genetic cause of chronic renal failure in adults.

Epidemiology

  • Polycystic kidney disease is the most common life-threatening genetic disease, affecting approximately 7 million people worldwide. Autosomal dominant polycystic kidney disease affects up to 1 in 1000 people, while the autosomal recessive type is estimated to occur in approximately 1 in 20,000 people.[1][2]
  • It affects men and women equally

References

  1. DALGAARD OZ (1957). "Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families". Acta Med. Scand. Suppl. 328: 1–255. PMID 13469269.
  2. Zerres K, Mücher G, Becker J; et al. (1998). "Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology". Am. J. Med. Genet. 76 (2): 137–44. PMID 9511976.

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