Pneumoconiosis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

• The symptoms of pneumoconiosis typically develop ___ years after exposure to ___.
• If left untreated, [#]% of patients with pneumconiosis may progress to develop pulmonary fibrosis and respiratory failure.

Complications

• Common complications of pneumoconiosis include:
  • Pulmonary fibrosis
  • Emphysema
  • COPD
  • Pleural effusion
  • Pleural plaques
  • Malignant Mesothelioma (Asbestosis)
  • Carcinoma
  • Tuberculosis
  • Scleroderma
  • SLE
  • Glomerulonephritis
  • Pulmonary hypertension
  • Cor pulmonale
  • Respiratory failure

Prognosis

• Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
• Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
• The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
• [Subtype of disease/malignancy] is associated with the most favorable prognosis.
• The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

• The prognosis for pneumoconiosis is poor and leads to respiratory complications and premature death. The prognosis is deemed to be poor particularly when fibrosis is found on CT scans.