Parathyroid adenoma epidemiology and demographics: Difference between revisions

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{{Parathyroid adenoma}}
{{Parathyroid adenoma}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{sali}}
==Overview==
==Overview==
A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism<ref name="pmid29022783">{{cite journal |vauthors=Edafe O, Collins EE, Ubhi CS, Balasubramanian SP |title=Current predictive models do not accurately differentiate between single and multi gland disease in primary hyperparathyroidism: a retrospective cohort study of two endocrine surgery units |journal=Ann R Coll Surg Engl |volume=100 |issue=2 |pages=140–145 |date=February 2018 |pmid=29022783 |pmc=5838681 |doi=10.1308/rcsann.2017.0112 |url=}}</ref>. A double adenomas the culprit in 4% to 5%, and parathyroid hyperplasia in 10% to 12%<ref name="pmid29939647">{{cite journal |vauthors=Wolfe SA, Sharma S |title= |journal= |volume= |issue= |pages= |date= |pmid=29939647 |doi= |url=}}</ref>. Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease. Adenomas are most common in patients 50 to 70 years old.They can occur at any age. Women are affected 3-times as often as men


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
* A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism<ref name="pmid23418315">{{cite journal |vauthors=Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, Haigh PI, Adams AL |title=Incidence and prevalence of primary hyperparathyroidism in a racially mixed population |journal=J. Clin. Endocrinol. Metab. |volume=98 |issue=3 |pages=1122–9 |date=March 2013 |pmid=23418315 |pmc=3590475 |doi=10.1210/jc.2012-4022 |url=}}</ref>.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
* Approximately 100,000 Americans develop primary hyperparathyroidism each year from parathyroid adenoma<ref name="pmid30093752">{{cite journal |vauthors=Pamathy G, Jayarajah U, Wangmo T, Banagala ASK |title=Lithium-induced Symptomatic Hypercalcemia and Hyperparathyroidism in a Patient with Bipolar Affective Disorder: A Case Report and Review of Literature |journal=Indian J Psychol Med |volume=40 |issue=4 |pages=378–380 |date=2018 |pmid=30093752 |pmc=6065126 |doi=10.4103/IJPSYM.IJPSYM_305_17 |url=}}</ref>.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.


===Case-fatality rate/Mortality rate===
===Incidence===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
* A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism.  
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].
* Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease.


===Age===
===Age===
*Patients of all age groups may develop [disease name].
* They can occur at any age<ref name="pmid28775107">{{cite journal |vauthors=Sahli ZT, Karipineni F, Zeiger MA |title=A garden of parathyroid adenomas |journal=BMJ Case Rep |volume=2017 |issue= |pages= |date=August 2017 |pmid=28775107 |pmc=5747797 |doi=10.1136/bcr-2017-221130 |url=}}</ref>.
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
*There is no racial predilection to [disease name].
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
===Gender===
===Gender===
*[Disease name] affects men and women equally.
* Women are affected 3-times as often as men
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
 
===Region===
*The majority of [disease name] cases are reported in [geographical region].
 
*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
 
===Developed Countries===
 
===Developing Countries===


==References==
==References==

Latest revision as of 12:11, 2 October 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Musadiq Ali M.B.B.S.[2]

Overview

A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism[1]. A double adenomas the culprit in 4% to 5%, and parathyroid hyperplasia in 10% to 12%[2]. Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease. Adenomas are most common in patients 50 to 70 years old.They can occur at any age. Women are affected 3-times as often as men

Epidemiology and Demographics

Prevalence

  • A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism[3].
  • Approximately 100,000 Americans develop primary hyperparathyroidism each year from parathyroid adenoma[4].

Incidence

  • A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism.
  • Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease.

Age

  • They can occur at any age[5].

Gender

  • Women are affected 3-times as often as men

References

  1. Edafe O, Collins EE, Ubhi CS, Balasubramanian SP (February 2018). "Current predictive models do not accurately differentiate between single and multi gland disease in primary hyperparathyroidism: a retrospective cohort study of two endocrine surgery units". Ann R Coll Surg Engl. 100 (2): 140–145. doi:10.1308/rcsann.2017.0112. PMC 5838681. PMID 29022783.
  2. Wolfe SA, Sharma S. PMID 29939647. Missing or empty |title= (help)
  3. Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, Haigh PI, Adams AL (March 2013). "Incidence and prevalence of primary hyperparathyroidism in a racially mixed population". J. Clin. Endocrinol. Metab. 98 (3): 1122–9. doi:10.1210/jc.2012-4022. PMC 3590475. PMID 23418315.
  4. Pamathy G, Jayarajah U, Wangmo T, Banagala A (2018). "Lithium-induced Symptomatic Hypercalcemia and Hyperparathyroidism in a Patient with Bipolar Affective Disorder: A Case Report and Review of Literature". Indian J Psychol Med. 40 (4): 378–380. doi:10.4103/IJPSYM.IJPSYM_305_17. PMC 6065126. PMID 30093752. Vancouver style error: initials (help)
  5. Sahli ZT, Karipineni F, Zeiger MA (August 2017). "A garden of parathyroid adenomas". BMJ Case Rep. 2017. doi:10.1136/bcr-2017-221130. PMC 5747797. PMID 28775107.

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