Parathyroid adenoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Musadiq Ali M.B.B.S.[2]

Overview

A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism[1]. A double adenomas the culprit in 4% to 5%, and parathyroid hyperplasia in 10% to 12%[2]. Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease. Adenomas are most common in patients 50 to 70 years old.They can occur at any age. Women are affected 3-times as often as men

Epidemiology and Demographics

Prevalence

  • A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism[3].
  • Approximately 100,000 Americans develop primary hyperparathyroidism each year from parathyroid adenoma[4].

Incidence

  • A single parathyroid adenoma is responsible for 80% to 85% of hyperparathyroidism.
  • Parathyroid carcinomas are very rare causes of hyperparathyroidism and account for less than 1% of disease.

Age

  • They can occur at any age[5].

Gender

  • Women are affected 3-times as often as men

References

  1. Edafe O, Collins EE, Ubhi CS, Balasubramanian SP (February 2018). "Current predictive models do not accurately differentiate between single and multi gland disease in primary hyperparathyroidism: a retrospective cohort study of two endocrine surgery units". Ann R Coll Surg Engl. 100 (2): 140–145. doi:10.1308/rcsann.2017.0112. PMC 5838681. PMID 29022783.
  2. Wolfe SA, Sharma S. PMID 29939647. Missing or empty |title= (help)
  3. Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, Haigh PI, Adams AL (March 2013). "Incidence and prevalence of primary hyperparathyroidism in a racially mixed population". J. Clin. Endocrinol. Metab. 98 (3): 1122–9. doi:10.1210/jc.2012-4022. PMC 3590475. PMID 23418315.
  4. Pamathy G, Jayarajah U, Wangmo T, Banagala A (2018). "Lithium-induced Symptomatic Hypercalcemia and Hyperparathyroidism in a Patient with Bipolar Affective Disorder: A Case Report and Review of Literature". Indian J Psychol Med. 40 (4): 378–380. doi:10.4103/IJPSYM.IJPSYM_305_17. PMC 6065126. PMID 30093752. Vancouver style error: initials (help)
  5. Sahli ZT, Karipineni F, Zeiger MA (August 2017). "A garden of parathyroid adenomas". BMJ Case Rep. 2017. doi:10.1136/bcr-2017-221130. PMC 5747797. PMID 28775107.

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