Parathyroid adenoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

Parathyroid adenoma may be classified according to location into 7 subtypes from type A gland to type G gland.

Classification

Parathyroid adenoma may be classified according to location into 7 subtypes: [1][1][2][3]

Type Location
Type A
  • Adherent to the posterior thyroid parenchyma
  • Expected location of a normal gland
  • Almost attached
  • Almost intracapsular
Type B
  • Back behind the thyroid parenchyma
  • Exophytic to the thyroid parenchyma
  • Lies in the tracheoesophageal groove
  • B+ gland: An undescended gland high in the neck near the carotid bifurcation or mandible
Type C
  • Could be mistaken for the esophagus when palpated
  • Caudal to the thyroid parenchyma, in the tracheoesophageal groove
  • More inferior than a type B gland on lateral views
  • Situated at the level of the inferior pole of the thyroid or inferior to the inferior pole of the thyroid (closer to the clavicle)
Type D
  • Dissection is difficult as the gland is dangerously close to the recurrent laryngeal nerve
Type E
  • The most externally located gland
  • Easy to resect
Type F
  • Fallen into the thyrothymic ligament
  • May be referred as "ectopic"
  • Can be usually retrieved with delivery of the superior portion of the thymus
Type G
  • Got caught in thyroid tissue
  • Gated into the thyroid parenchyma
  • A true intra intrathyroidal gland is rare

References

  1. 1.0 1.1 Perrier ND, Edeiken B, Nunez R, Gayed I, Jimenez C, Busaidy N; et al. (2009). "A novel nomenclature to classify parathyroid adenomas". World J Surg. 33 (3): 412–6. doi:10.1007/s00268-008-9894-0. PMID 19148701.
  2. Hamidi S, Hedayat A, Esfahanian F, Kamalian N (October 2007). "Distribution of solitary parathyroid adenoma over the parathyroid glands and its surgical management". J Coll Physicians Surg Pak. 17 (10): 619–21. doi:10.2007/JCPSP.619621. PMID 17999854.
  3. Debruyne F, Ostyn F, Delaere P (May 1997). "Distribution of the solitary adenoma over the parathyroid glands". J Laryngol Otol. 111 (5): 459–60. doi:10.1017/s0022215100137636. PMID 9205609.

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