Lactic acidosis risk factors: Difference between revisions

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* Diabetics taking metformin and SGLT2 inhibitors, especially in conjunction with active COVID-19<ref name="pmid32413342">{{cite journal| author=Orioli L, Hermans MP, Thissen JP, Maiter D, Vandeleene B, Yombi JC| title=COVID-19 in diabetic patients: Related risks and specifics of management. | journal=Ann Endocrinol (Paris) | year= 2020 | volume= 81 | issue= 2-3 | pages= 101-109 | pmid=32413342 | doi=10.1016/j.ando.2020.05.001 | pmc=7217100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32413342  }} </ref>
== Overview ==
* Underlying sepsis  
Risk factors associated with the development of lactic acidosis are:
* Septic, cardiogenic or haemorrhagic shock
 
*  
*Diabetics taking metformin and SGLT2 inhibitors, especially in conjunction with active COVID-19<ref name="pmid32413342">{{cite journal| author=Orioli L, Hermans MP, Thissen JP, Maiter D, Vandeleene B, Yombi JC| title=COVID-19 in diabetic patients: Related risks and specifics of management. | journal=Ann Endocrinol (Paris) | year= 2020 | volume= 81 | issue= 2-3 | pages= 101-109 | pmid=32413342 | doi=10.1016/j.ando.2020.05.001 | pmc=7217100 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32413342  }} </ref>
*Underlying sepsis
*Septic, cardiogenic or haemorrhagic shock
 
<br />
 
== Risk factors ==
Reported predisposing factors include
 
* Acute kidney injury
* Previous history of lactic acidosis;
* Hypovolemia;
* Decreased tissue perfusion
* Hemodynamic instability due to infection or other causes;
* Seizure;
* Concurrent liver disease;
* Alcohol abuse;
* Acute heart failure;
* Myocardial infarction;
* Shock due to any cause
 
*
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Revision as of 09:17, 15 December 2021

Overview

Risk factors associated with the development of lactic acidosis are:

  • Diabetics taking metformin and SGLT2 inhibitors, especially in conjunction with active COVID-19[1]
  • Underlying sepsis
  • Septic, cardiogenic or haemorrhagic shock


Risk factors

Reported predisposing factors include

  • Acute kidney injury
  • Previous history of lactic acidosis;
  • Hypovolemia;
  • Decreased tissue perfusion
  • Hemodynamic instability due to infection or other causes;
  • Seizure;
  • Concurrent liver disease;
  • Alcohol abuse;
  • Acute heart failure;
  • Myocardial infarction;
  • Shock due to any cause

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References

  1. Orioli L, Hermans MP, Thissen JP, Maiter D, Vandeleene B, Yombi JC (2020). "COVID-19 in diabetic patients: Related risks and specifics of management". Ann Endocrinol (Paris). 81 (2–3): 101–109. doi:10.1016/j.ando.2020.05.001. PMC 7217100 Check |pmc= value (help). PMID 32413342 Check |pmid= value (help).


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