Kawasaki disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
Kawasaki disease often begins with a high and persistent fever that is not very responsive to normal doses of acetaminophen or ibuprofen. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop red eyes, mucous membranes, and lips, a "strawberry tongue", iritis, keratic precipitates (detectable by an ophthalmologist but usually too small to be seen by the naked eye), and swollen lymph nodes. Skin rashes occur early in the disease, and peeling of the skin in the genital area, hands, and feet may occur in later phases. Some of these symptoms may come and go during the course of the illness.
History and Symptoms
Kawasaki disease often begins with a high and persistent fever that is not very responsive to normal doses of acetaminophen or ibuprofen. The fever may persist and rise steadily for up to two weeks and is normally accompanied by irritability. Affected children develop red eyes, mucous membranes, and lips, a "strawberry tongue", iritis, keratic precipitates (detectable by an ophthalmologist but usually too small to be seen by the naked eye), and swollen lymph nodes. Skin rashes occur early in the disease, and peeling of the skin in the genital area, hands, and feet may occur in later phases. Some of these symptoms may come and go during the course of the illness.[1]
- High-grade fever (greater than 39 °C or 102 °F; often as high as 40 °C or 104 °F) that normally lasts for more than a week if left untreated.
- Red eyes (conjunctivitis) without pus or drainage, also known as "conjunctival injection"
- Bright red, chapped, or cracked lips
- Red mucous membranes in the mouth
- Strawberry tongue, white coating on the tongue or prominent red bumps (papillae) on the back of the tongue
- Red palms of the hands and the soles of the feet
- Swollen hands and feet
- Rash which may take many forms, but not vesicular (blister-like), on the trunk
- Swollen lymph nodes (frequently only one lymph node is swollen), particularly in the neck area
- Joint pain (arthralgia) and swelling, frequently symmetrical
- Irritability
- Tachycardia (rapid heart beat)
- Peeling (desquamation) palms and soles (later in the illness); peeling may begin around the nails
References
- ↑ McCrindle, Brian W.; Rowley, Anne H.; Newburger, Jane W.; Burns, Jane C.; Bolger, Anne F.; Gewitz, Michael; Baker, Annette L.; Jackson, Mary Anne; Takahashi, Masato; Shah, Pinak B.; Kobayashi, Tohru; Wu, Mei-Hwan; Saji, Tsutomu T.; Pahl, Elfriede (2017). "Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association". Circulation. 135 (17): e927–e999. doi:10.1161/CIR.0000000000000484. ISSN 0009-7322.