Jaundice history & symptoms

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Jaundice Microchapters


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Historical Perspective




Differentiating Jaundice from other Conditions

Epidemiology and Demographics

Risk Factors


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History and Symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]


Common symptoms associated with jaundice are yellowing of the skin, nausea, and vomiting. Specific symptoms will depend on the underlying cause of jaundice. Patients may present with fever, anorexia, dark urine, fatigue, pruritis, right upper quadrant pain. A detailed history of alcohol use, blood transfusions, history of viral hepatitis and family history of liver disease is recommended for all the patients.

History and Symptoms

  • Jaundice typically progress in "top to bottom" manner, from face to feet.
  • Specific history should be focused on alcohol or hepatotoxic medication use.


Patients with jaundice may have a positive history of:

Social history

  • History of alcohol use:
    • Amount
    • Duration
  • History of illicit drug use
  • History of unprotected sexual intercourse

Past Medical history

Family history

Medication history

Common Symptoms

Common symptoms of jaundice depends on the underlying factor that causes jaundice and include:

Less Common Symptoms

Less common symptoms of jaundice include


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