Immunodeficiency
Immunodeficiency | |
ICD-10 | D84.9 |
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ICD-9 | 279.3 |
DiseasesDB | 21506 |
MeSH | D007153 |
Immunodeficiency Main Page |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[3], Ali Akram, M.B.B.S.[4], Zahir Ali Shaikh, MD[5] , Syed Musadiq Ali M.B.B.S.[6], Sabawoon Mirwais, M.B.B.S, M.D.[7]
Synonyms and keywords: Immune deficiency; immunity suppression; immunological deficiency; immunosuppression
Overview
Immunodeficiency can be caused by a variety of conditions including autoimmunity, infections, congenital defects, complement defects, or auto-inflammatory states.
Classification
Immunodeficiency | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Immunodeficiency affecting cellular and humoral Immunity | Combined immunodeficiency | Predominantly antibody deficiency | Diseases of immune dysregulation | Congenital defects of phagocytes | Defects in intrinsic and innate immunity | Auto-inflammatory disorders | Complement deficiencies | Phenocopies of primary immunodeficiency (PID) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Severe combined immunodeficiency (SCID) | Combined immunodeficiency with associated features | Hypogammaglobulinemia | Hemophagocytic lymphohistiocytosis (HLH) & EBV susceptibility | Congenital defects of phagocyte number | Bacterial and parasitic infections | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Combined immunodeficiencies generally less pronounced than severe combined immunodeficiency | Combined immunodeficiency with syndromic features | Other antibody deficiencies | Syndromes with autoimmunity and others | Congenital defects of phagocyte function | Mendelian susceptibility to mycobacterial disease (MSMD) & viral infections | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||