Esophageal cancer history and symptoms: Difference between revisions

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{{Esophageal cancer}}
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==Overview==
==Overview==
Patient history in esophageal cancer includes pain in the throat or chest, regurgitation of food and [[Dysphonia|hoarseness]] of voice. Symptoms of esophageal cancer include [[Dysphagia (patient information)|dysphagia]], [[Odynophagia (patient information)|odynophagia]], [[weight loss]], and [[hematemesis]]. It should be noted that superficial esophageal cancer may have an insidious onset, so screening for [[Barrett's esophagus]] is important in this case to diagnose cancer earlier.


==Signs and symptoms==
==History==
Dysphagia (difficulty swallowing) is the first symptom in most patients. [[Odynophagia]] (painful swallowing) may be present. Fluids and soft foods are usually tolerated, while hard or bulky substances (such as bread or meat) cause much more difficulty. Substantial [[weight loss]] is characteristic as a result of poor nutrition and the active cancer. [[Pain and nociception|Pain]], often of a burning nature, may be severe and worsened by swallowing, and can be spasmodic in character.  An early sign may be an unusually husky or raspy voice. 


The presence of the tumor may disrupt normal [[peristalsis]] (the organised swallowing reflex), leading to [[nausea]] and [[vomiting]], [[regurgitation]] of food, [[cough]]ing and an increased risk of [[aspiration pneumonia]]. The tumor surface may be fragile and [[hemorrhage|bleed]], causing [[hematemesis]] (vomiting up blood). Compression of local structures occurs in advanced disease, leading to such problems as [[superior vena cava syndrome]]. [[Fistula]]s may develop between the esophagus and the [[Vertebrate trachea|trachea]], increasing the pneumonia risk; this symptom is usually heralded by [[cough]], [[fever]] or aspiration.<ref name=Enzinger/>
Obtaining history is an important aspect of making a diagnosis of esophageal cancer. It provides an insight into severity, precipitating factors and associated comorbid conditions. Complete history will help determine the correct therapy and helps in determining the prognosis. The areas of focus should be on onset, duration, and progression of symptoms such as:<ref name="pmid8888335">{{cite journal |vauthors=Trate DM, Parkman HP, Fisher RS |title=Dysphagia. Evaluation, diagnosis, and treatment |journal=Prim. Care |volume=23 |issue=3 |pages=417–32 |year=1996 |pmid=8888335 |doi= |url=}}</ref><ref name="pmid8705259">{{cite journal |vauthors=Spechler SJ |title=Barrett's esophagus |journal=Semin. Gastrointest. Dis. |volume=7 |issue=2 |pages=51–60 |year=1996 |pmid=8705259 |doi= |url=}}</ref>
*[[Dysphagia (patient information)|Difficulty swallowing]]
*[[Odynophagia (patient information)|Painful swallowing]]
**Fluids and soft foods are usually tolerated, while hard or bulky substances (such as bread or meat) cause pain during swallowing.
*[[Weight loss]]
*[[Pain and nociception|Pain]]
**Often of a burning nature, may be severe and worsened by swallowing, and can be spasmodic in character.
*[[Nausea]]
*[[Vomiting]]
*[[Regurgitation]] of food
*[[Cough]]ing
*[[Aspiration pneumonia| History of previous pneumonia]]
*[[Hematemesis|Bloody cough or bloody saliva]]
*[[Hoarseness]]
*[[Vocal cord paralysis]]


If the disease has [[metastasis|spread]] elsewhere, this may lead to symptoms related to this: [[liver]] metastasis could cause [[jaundice]] and [[ascites]], [[lung]] metastasis could cause [[dyspnea|shortness of breath]], [[pleural effusion]]s, etc.
 
==Common symptoms==
Common symptoms include:<ref name="pmid7557137">{{cite journal |vauthors=Cameron AJ, Lomboy CT, Pera M, Carpenter HA |title=Adenocarcinoma of the esophagogastric junction and Barrett's esophagus |journal=Gastroenterology |volume=109 |issue=5 |pages=1541–6 |year=1995 |pmid=7557137 |doi= |url=}}</ref><ref name="pmid7815789">{{cite journal |vauthors=Lieberman MD, Shriver CD, Bleckner S, Burt M |title=Carcinoma of the esophagus. Prognostic significance of histologic type |journal=J. Thorac. Cardiovasc. Surg. |volume=109 |issue=1 |pages=130–8; discussion 139 |year=1995 |pmid=7815789 |doi=10.1016/S0022-5223(95)70428-0 |url=}}</ref>
*[[Dysphagia]] to solid food
*Retrosternal or burning pain
*[[Weight loss]]
*Changes in diet
*[[Anorexia]]
Less common symptoms include:
*[[Regurgitation (digestion)|Regurgitation]] of food or saliva<ref name="pmid7557137">{{cite journal |vauthors=Cameron AJ, Lomboy CT, Pera M, Carpenter HA |title=Adenocarcinoma of the esophagogastric junction and Barrett's esophagus |journal=Gastroenterology |volume=109 |issue=5 |pages=1541–6 |year=1995 |pmid=7557137 |doi= |url=}}</ref><ref name="pmid7815789">{{cite journal |vauthors=Lieberman MD, Shriver CD, Bleckner S, Burt M |title=Carcinoma of the esophagus. Prognostic significance of histologic type |journal=J. Thorac. Cardiovasc. Surg. |volume=109 |issue=1 |pages=130–8; discussion 139 |year=1995 |pmid=7815789 |doi=10.1016/S0022-5223(95)70428-0 |url=}}</ref>
*[[Dysphonia|Hoarseness]] or loss of voice
*Bloody or intractable [[cough]]
*[[Melena|Blood in stools]]
*Frequent [[pneumonia]]


==References==
==References==
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Latest revision as of 16:37, 27 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Patient history in esophageal cancer includes pain in the throat or chest, regurgitation of food and hoarseness of voice. Symptoms of esophageal cancer include dysphagia, odynophagia, weight loss, and hematemesis. It should be noted that superficial esophageal cancer may have an insidious onset, so screening for Barrett's esophagus is important in this case to diagnose cancer earlier.

History

Obtaining history is an important aspect of making a diagnosis of esophageal cancer. It provides an insight into severity, precipitating factors and associated comorbid conditions. Complete history will help determine the correct therapy and helps in determining the prognosis. The areas of focus should be on onset, duration, and progression of symptoms such as:[1][2]


Common symptoms

Common symptoms include:[3][4]

Less common symptoms include:

References

  1. Trate DM, Parkman HP, Fisher RS (1996). "Dysphagia. Evaluation, diagnosis, and treatment". Prim. Care. 23 (3): 417–32. PMID 8888335.
  2. Spechler SJ (1996). "Barrett's esophagus". Semin. Gastrointest. Dis. 7 (2): 51–60. PMID 8705259.
  3. 3.0 3.1 Cameron AJ, Lomboy CT, Pera M, Carpenter HA (1995). "Adenocarcinoma of the esophagogastric junction and Barrett's esophagus". Gastroenterology. 109 (5): 1541–6. PMID 7557137.
  4. 4.0 4.1 Lieberman MD, Shriver CD, Bleckner S, Burt M (1995). "Carcinoma of the esophagus. Prognostic significance of histologic type". J. Thorac. Cardiovasc. Surg. 109 (1): 130–8, discussion 139. doi:10.1016/S0022-5223(95)70428-0. PMID 7815789.


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