Celiac disease overview: Difference between revisions
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'''Celiac disease''' is an [[Autoimmunity|autoimmune]] disorder of the [[small bowel]] that occurs in [[Genetic predisposition|genetically predisposed]] people of all ages from middle infancy. Symptoms include chronic [[diarrhoea]], [[failure to thrive]] (in children) and [[fatigue (physical)|fatigue]], but these may be absent and symptoms in all other organ systems have been described. It is estimated to affect about 1% of Indo-European populations, although significantly underdiagnosed. A growing portion of diagnoses are being made in asymptomatic persons as a result of increasing screening.<ref name=VanHeelWest>{{cite journal | author = van Heel D, West J | title = Recent advances in coeliac disease | url = http://gut.bmjjournals.com/cgi/content/full/55/7/1037 | journal = Gut | volume = 55 | issue = 7 | pages = 1037–46 | year = 2006 | id = PMID 16766754}}</ref> | '''Celiac disease''' is an [[Autoimmunity|autoimmune]] disorder of the [[small bowel]] that occurs in [[Genetic predisposition|genetically predisposed]] people of all ages from middle infancy. Symptoms include chronic [[diarrhoea]], [[failure to thrive]] (in children) and [[fatigue (physical)|fatigue]], but these may be absent and symptoms in all other organ systems have been described. It is estimated to affect about 1% of Indo-European populations, although significantly underdiagnosed. A growing portion of diagnoses are being made in asymptomatic persons as a result of increasing screening.<ref name=VanHeelWest>{{cite journal | author = van Heel D, West J | title = Recent advances in coeliac disease | url = http://gut.bmjjournals.com/cgi/content/full/55/7/1037 | journal = Gut | volume = 55 | issue = 7 | pages = 1037–46 | year = 2006 | id = PMID 16766754}}</ref> | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating Celiac Disease from other Diseases== | |||
==Epidemiology and Demographics== | |||
==Risk Factors== | |||
==Natural History, Complications and Prognosis== | |||
==Diagnosis== | |||
===History and Symptoms=== | |||
===Physical Examination=== | |||
===Laboratory Findings=== | |||
===Electrocardiogram=== | |||
===Chest X Ray=== | |||
===CT Scan=== | |||
===Echocardiography or Ultrasound=== | |||
===Other Imaging Findings=== | |||
==Treatment== | |||
===Medical Therapy=== | |||
===Surgery=== | |||
===Primary Prevention=== | |||
===Secondary Prevention=== | |||
===Future or Investigational Therapies=== | |||
==References== | ==References== | ||
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[[Category:Rheumatology]] |
Revision as of 14:57, 10 June 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
American Gastroenterological Association (AGA) Definition: “Chronic malabsorptive disorder of the small intestine caused by exposure to dietary gluten in genetically predisposed individuals”
Celiac disease is an autoimmune disorder of the small bowel that occurs in genetically predisposed people of all ages from middle infancy. Symptoms include chronic diarrhoea, failure to thrive (in children) and fatigue, but these may be absent and symptoms in all other organ systems have been described. It is estimated to affect about 1% of Indo-European populations, although significantly underdiagnosed. A growing portion of diagnoses are being made in asymptomatic persons as a result of increasing screening.[1]
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Celiac Disease from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT Scan
Echocardiography or Ultrasound
Other Imaging Findings
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Future or Investigational Therapies
References
- ↑ van Heel D, West J (2006). "Recent advances in coeliac disease". Gut. 55 (7): 1037–46. PMID 16766754.