Cardiac amyloidosis natural history, complications and prognosis: Difference between revisions

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The following are the complications of CA:
The following are the complications of CA:
* [[Congestive heart failure]]<ref name="pmid23391947">{{cite journal |author=Shah S, Dungu J, Dubrey SW |title=Senile cardiac amyloidosis: an underappreciated cause of heart failure |journal=[[BMJ Case Reports]] |volume=2013 |issue= |pages= |year=2013 |pmid=23391947 |doi=10.1136/bcr-2012-007635 |url=}}</ref><ref name="pmid23474361">{{cite journal |author=Swiecicki PL, Edwards BS, Kushwaha SS, Dispenzieri A, Park SJ, Gertz MA |title=Left ventricular device implantation for advanced cardiac amyloidosis |journal=[[The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation]] |volume=32 |issue=5 |pages=563–8 |year=2013 |month=May |pmid=23474361 |doi=10.1016/j.healun.2013.01.987 |url=}}</ref>
* [[Congestive heart failure]]<ref name="pmid23391947">{{cite journal |author=Shah S, Dungu J, Dubrey SW |title=Senile cardiac amyloidosis: an underappreciated cause of heart failure |journal=[[BMJ Case Reports]] |volume=2013 |issue= |pages= |year=2013 |pmid=23391947 |doi=10.1136/bcr-2012-007635 |url=}}</ref><ref name="pmid23474361">{{cite journal |author=Swiecicki PL, Edwards BS, Kushwaha SS, Dispenzieri A, Park SJ, Gertz MA |title=Left ventricular device implantation for advanced cardiac amyloidosis |journal=[[The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation]] |volume=32 |issue=5 |pages=563–8 |year=2013 |month=May |pmid=23474361 |doi=10.1016/j.healun.2013.01.987 |url=}}</ref>
* [[Sudden cardiac death]]<ref name="pmid22301727">{{cite journal |author=Edler C, Saeger W, Orth U, Braun C, Wulff B, Sperhake J |title=[Hereditary cardiac amyloidosis with transthyretin mutations. A cause of sudden death ] |language=German |journal=[[Herz]] |volume=37 |issue=4 |pages=456–60 |year=2012 |month=June |pmid=22301727 |doi=10.1007/s00059-011-3566-9 |url=}}</ref> due to electromechanical dissociation.
* [[Sudden cardiac death]] ([[SCD]])<ref name="pmid22301727">{{cite journal |author=Edler C, Saeger W, Orth U, Braun C, Wulff B, Sperhake J |title=[Hereditary cardiac amyloidosis with transthyretin mutations. A cause of sudden death ] |language=German |journal=[[Herz]] |volume=37 |issue=4 |pages=456–60 |year=2012 |month=June |pmid=22301727 |doi=10.1007/s00059-011-3566-9 |url=}}</ref> due to electromechanical dissociation unlike SCD due to other causes.
* [[Myocardial infarction]]<ref name="pmid21747665">{{cite journal |author=Mugnai G, Cicoira M, Rossi A, Vassanelli C |title=Syncope in cardiac amyloidosis and chronic ischemic heart disease: A case report |journal=[[Experimental and Clinical Cardiology]] |volume=16 |issue=2 |pages=51–3 |year=2011 |pmid=21747665 |pmc=3126684 |doi= |url=}}</ref>
* [[Myocardial infarction]]<ref name="pmid21747665">{{cite journal |author=Mugnai G, Cicoira M, Rossi A, Vassanelli C |title=Syncope in cardiac amyloidosis and chronic ischemic heart disease: A case report |journal=[[Experimental and Clinical Cardiology]] |volume=16 |issue=2 |pages=51–3 |year=2011 |pmid=21747665 |pmc=3126684 |doi= |url=}}</ref>
* [[Pericardial effusion]]<ref name="pmid7091168">{{cite journal |author=Brodarick S, Paine R, Higa E, Carmichael KA |title=Pericardial tamponade, a new complication of amyloid heart disease |journal=[[The American Journal of Medicine]] |volume=73 |issue=1 |pages=133–5 |year=1982 |month=July |pmid=7091168 |doi= |url=}}</ref>
* [[Pericardial effusion]]<ref name="pmid7091168">{{cite journal |author=Brodarick S, Paine R, Higa E, Carmichael KA |title=Pericardial tamponade, a new complication of amyloid heart disease |journal=[[The American Journal of Medicine]] |volume=73 |issue=1 |pages=133–5 |year=1982 |month=July |pmid=7091168 |doi= |url=}}</ref>

Revision as of 04:04, 12 May 2013

Cardiac amyloidosis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]; Cafer Zorkun, M.D., Ph.D. [4]; Lakshmi Gopalakrishnan, M.B.B.S. [5]

Overview

The presence or absence of cardiac involvement with amyloid is the most important prognostic factor.[1]

Natural History

If untreated cardiac amyloidosis (CA) is associate with high complication rate and eventually death. Cardiac involvement in AL amyloidosis is associated with a higher mortality rate compared with that in senile and familial forms of amyloidosis. Also, heart failure in AL type CA is difficult to treat adequately compared with that associated with TTR type.

Complications

The following are the complications of CA:

Prognosis

Cardiac amyloidosis is a chronic and progressive condition. A cardiologist may estimate the prognosis according to the thickness of the left ventricle and to the degree of restriction in the heart (diastolic dysfunction).

References

  1. Gertz MA, Lacy MQ, Dispenzieri A (1999). "Amyloidosis: recognition, confirmation, prognosis, and therapy". Mayo Clinic Proceedings. Mayo Clinic. 74 (5): 490–4. doi:10.4065/74.5.490. PMID 10319082. Retrieved 2012-02-13. Unknown parameter |month= ignored (help)
  2. Shah S, Dungu J, Dubrey SW (2013). "Senile cardiac amyloidosis: an underappreciated cause of heart failure". BMJ Case Reports. 2013. doi:10.1136/bcr-2012-007635. PMID 23391947.
  3. Swiecicki PL, Edwards BS, Kushwaha SS, Dispenzieri A, Park SJ, Gertz MA (2013). "Left ventricular device implantation for advanced cardiac amyloidosis". The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 32 (5): 563–8. doi:10.1016/j.healun.2013.01.987. PMID 23474361. Unknown parameter |month= ignored (help)
  4. Edler C, Saeger W, Orth U, Braun C, Wulff B, Sperhake J (2012). "[Hereditary cardiac amyloidosis with transthyretin mutations. A cause of sudden death ]". Herz (in German). 37 (4): 456–60. doi:10.1007/s00059-011-3566-9. PMID 22301727. Unknown parameter |month= ignored (help)
  5. 5.0 5.1 Mugnai G, Cicoira M, Rossi A, Vassanelli C (2011). "Syncope in cardiac amyloidosis and chronic ischemic heart disease: A case report". Experimental and Clinical Cardiology. 16 (2): 51–3. PMC 3126684. PMID 21747665.
  6. 6.0 6.1 Brodarick S, Paine R, Higa E, Carmichael KA (1982). "Pericardial tamponade, a new complication of amyloid heart disease". The American Journal of Medicine. 73 (1): 133–5. PMID 7091168. Unknown parameter |month= ignored (help)
  7. Navarro JF, Rivera M, Ortuño J (1992). "Cardiac tamponade as presentation of systemic amyloidosis". International Journal of Cardiology. 36 (1): 107–8. PMID 1428240. Unknown parameter |month= ignored (help)
  8. Yunis NA, Petrasko MS, Cannistra LB (2000). "An Elderly Man With Progressive Dyspnea on Exertion and Atrial Fibrillation as Manifestations of Senile Cardiac Amyloidosis". The American Journal of Geriatric Cardiology. 9 (2): 69–72. PMID 11416540. Unknown parameter |month= ignored (help)
  9. Cheng Z, Zhu K, Tian Z, Zhao D, Cui Q, Fang Q (2013). "The findings of electrocardiography in patients with cardiac amyloidosis". Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. 18 (2): 157–62. doi:10.1111/anec.12018. PMID 23530486. Unknown parameter |month= ignored (help)
  10. Lin G, Dispenzieri A, Brady PA (2010). "Successful termination of a ventricular arrhythmia by implantable cardioverter defibrillator therapy in a patient with cardiac amyloidosis: insight into mechanisms of sudden death". European Heart Journal. 31 (12): 1538. doi:10.1093/eurheartj/ehp592. PMID 20061577. Unknown parameter |month= ignored (help)
  11. Reisinger J, Dubrey SW, Lavalley M, Skinner M, Falk RH (1997). "Electrophysiologic abnormalities in AL (primary) amyloidosis with cardiac involvement". Journal of the American College of Cardiology. 30 (4): 1046–51. PMID 9316537. Unknown parameter |month= ignored (help)
  12. Feng D, Syed IS, Martinez M; et al. (2009). "Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis". Circulation. 119 (18): 2490–7. doi:10.1161/CIRCULATIONAHA.108.785014. PMID 19414641. Unknown parameter |month= ignored (help)
  13. Feng D, Edwards WD, Oh JK; et al. (2007). "Intracardiac thrombosis and embolism in patients with cardiac amyloidosis". Circulation. 116 (21): 2420–6. doi:10.1161/CIRCULATIONAHA.107.697763. PMID 17984380. Unknown parameter |month= ignored (help)


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