Anaplastic large cell lymphoma medical therapy
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Anaplastic large cell lymphoma Microchapters |
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Differentiating Anaplastic large cell lymphoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Anaplastic large cell lymphoma medical therapy On the Web |
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American Roentgen Ray Society Images of Anaplastic large cell lymphoma medical therapy |
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Directions to Hospitals Treating Anaplastic large cell lymphoma |
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Risk calculators and risk factors for Anaplastic large cell lymphoma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Medical Therapy
Chemotherapy
- Anaplastic large cell lymphoma usually responds well to chemotherapy, so it often has a good prognosis
- It is treated with the same combinations of chemotherapy drugs used to treat other aggressive lymphomas
- Drug Regimen: (CHOP) Cyclophosphamide AND Doxorubicin AND Vincristine AND Prednisone
Radiation therapy
- Radiation therapy is most often given after chemotherapy
- External beam radiation therapy may be used
- When the lymphoma cells are only in one area of the lymph nodes (stage I primary systemic anaplastic large cell lymphoma)
- For localized skin lesions in primary cutaneous anaplastic large cell lymphoma
Stem cell transplant
- A stem cell transplant may be offered to some people with anaplastic large cell lymphoma who relapse after initial treatment
- Overall better prognosis than other "Aggressive Lymphomas"
- ALK+ 5-year survival 70-80%
- ALK- 5-year survival 30-40%