Anaplastic large cell lymphoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]

Overview

Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults. Males are more commonly affected with anaplastic large cell lymphoma than females.[1]

Epidemiology and Demographics

Incidence

  • The incidence/prevalence of Anaplastic large cell lymphoma is approximately 2-8% of adult cases of non-Hodgkins lymphoma and as much as 30% of childhood non-Hodgkins lymphomas[2][3]

Prevalence

  • Prevalence for this condition is not known

Age

  • Patients of all age groups may develop anapastic large cell lymphoma.
  • Anaplastic large cell lymphoma is a common disease that tends to affect children or young adults.
  • ALK-positive anaplastic large cell lymphoma usually affects younger individuals (between 10 and 29 years).[4]
  • ALK-negative anaplastic large cell lymphoma usually affects older individuals (between 40-60 years).

Gender

  • Males are more commonly affected with anaplastic large cell lymphoma than females.[1]

References

  1. 1.0 1.1 Anaplastic large cell lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/anaplastic-large-cell-lymphoma/?region=on Accessed on October 7, 2015
  2. Jairajpuri ZS, Rana S, Khetrapal S, Talikoti MA, Jetley S (2014). "Extranodal anaplastic large cell lymphoma mimicking sarcoma: A report of an interesting case". Int J Appl Basic Med Res. 4 (Suppl 1): S50–2. doi:10.4103/2229-516X.140741. PMC 4181133. PMID 25298944.
  3. Maeda T, Wakasawa T, Shima Y, Tsuboi I, Aizawa S, Tamai I (2006). "Role of polyamines derived from arginine in differentiation and proliferation of human blood cells". Biol Pharm Bull. 29 (2): 234–9. PMID 16462024.
  4. Stein H, Foss HD, Dürkop H, Marafioti T, Delsol G, Pulford K; et al. (2000). "CD30(+) anaplastic large cell lymphoma: a review of its histopathologic, genetic, and clinical features". Blood. 96 (12): 3681–95. PMID 11090048.

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