4-dimethylaminophenol

Not to be confused with 4-Dimethylaminopyridine.

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4-dimethylaminophenol

Identifiers
CAS Number	619-60-3 N
3D model (JSmol)	Interactive image
ChemSpider	20816 Y
ECHA InfoCard
PubChem CID	22174
UNII	X387L5559O Y
InChI InChI=1S/C8H11NO/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3 Y Key: JVVRCYWZTJLJSG-UHFFFAOYSA-N Y InChI=1/C8H11NO/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3 Key: JVVRCYWZTJLJSG-UHFFFAOYAU
SMILES Oc1ccc(N(C)C)cc1
Properties
Chemical formula	C8H11NO
Molar mass	137.179 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

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List of terms related to 4-dimethylaminophenol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C₈H₁₁NO.

Uses

4-Dimethylaminophenol has been used as an antidote for cyanide poisoning. It has also been shown to be effective in treating hydrogen sulfide toxicity.

It works by generating methemoglobin.

This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.

In an animal model, it has shown effectiveness when given intramuscularly. Though, intramuscular injection should be avoid due to the probability of muscular necrosis after injection. Intravenous injection is recommended in a dose of 250mg.