SLC25A11: Difference between revisions

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{{Infobox_gene}}
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'''Mitochondrial 2-oxoglutarate/malate carrier protein''' is a [[protein]] that in humans is encoded by the ''SLC25A11'' [[gene]].<ref name="pmid10072597">{{cite journal | vauthors = Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F | title = Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3 | journal = Cytogenet Cell Genet | volume = 83 | issue = 3–4 | pages = 256–7 |date=Mar 1999 | pmid = 10072597 | pmc =  | doi =10.1159/000015198 }}</ref><ref name="pmid1457818">{{cite journal | vauthors = Iacobazzi V, Palmieri F, Runswick MJ, Walker JE | title = Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier | journal = DNA Seq | volume = 3 | issue = 2 | pages = 79–88 |date=Jan 1993 | pmid = 1457818 | pmc =  | doi 10.3109/10425179209034000}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8402| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
| HGNCid = 10981
| Symbol = SLC25A11
| AltSymbols =; OGC; SLC20A4
| OMIM = 604165
| ECnumber =
| Homologene = 2637
| MGIid = 1915113
| GeneAtlas_image1 = PBB_GE_SLC25A11_209003_at_tn.png
  | GeneAtlas_image2 = PBB_GE_SLC25A11_207088_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0005488 |text = binding}} {{GNF_GO|id=GO:0015367 |text = oxoglutarate:malate antiporter activity}}
| Component = {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005743 |text = mitochondrial inner membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006810 |text = transport}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8402
    | Hs_Ensembl = ENSG00000108528
    | Hs_RefseqProtein = NP_003553
    | Hs_RefseqmRNA = NM_003562
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 4781169
    | Hs_GenLoc_end = 4784208
    | Hs_Uniprot = Q02978
    | Mm_EntrezGene = 67863
    | Mm_Ensembl = ENSMUSG00000014606
    | Mm_RefseqmRNA = NM_024211
    | Mm_RefseqProtein = NP_077173
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 70460391
    | Mm_GenLoc_end = 70463188
    | Mm_Uniprot = Q5SX46
  }}
}}
'''Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11''', also known as '''SLC25A11''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8402| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Iacobazzi V, Palmieri F, Runswick MJ, Walker JE |title=Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier. |journal=DNA Seq. |volume=3 |issue= 2 |pages= 79-88 |year= 1993 |pmid= 1457818 |doi=  }}
*{{cite journal   |vauthors=Bisaccia F, Zara V, Capobianco L, etal |title=The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier |journal=Biochim. Biophys. Acta |volume=1292 |issue= 2 |pages= 281–88 |year= 1996 |pmid= 8597574 |doi=10.1016/0167-4838(95)00215-4 }}
*{{cite journal  | author=Bisaccia F, Zara V, Capobianco L, ''et al.'' |title=The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier. |journal=Biochim. Biophys. Acta |volume=1292 |issue= 2 |pages= 281-88 |year= 1996 |pmid= 8597574 |doi=  }}
*{{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal  | vauthors=Bisaccia F, Capobianco L, Mazzeo M, Palmieri F |title=The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224 |journal=FEBS Lett. |volume=392 |issue= 1 |pages= 54–8 |year= 1996 |pmid= 8769314 |doi=10.1016/0014-5793(96)00784-3 }}
*{{cite journal  | author=Bisaccia F, Capobianco L, Mazzeo M, Palmieri F |title=The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224. |journal=FEBS Lett. |volume=392 |issue= 1 |pages= 54-8 |year= 1996 |pmid= 8769314 |doi=  }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-Scale Concatenation cDNA Sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Palmisano A, Zara V, Hönlinger A, etal |title=Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane |journal=Biochem. J. |volume=333 ( Pt 1) |issue=  Pt 1|pages= 151–8 |year= 1998 |pmid= 9639574 |doi=  | pmc=1219567 }}
*{{cite journal | author=Palmisano A, Zara V, Hönlinger A, ''et al.'' |title=Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane. |journal=Biochem. J. |volume=333 ( Pt 1) |issue=  |pages= 151-8 |year= 1998 |pmid= 9639574 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Piccininni S, Iacobazzi V, Lauria G, ''et al.'' |title=Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3. |journal=Cytogenet. Cell Genet. |volume=83 |issue= 3-4 |pages= 256-7 |year= 1999 |pmid= 10072597 |doi=  }}
*{{cite journal   |vauthors=Coll O, Colell A, García-Ruiz C, etal |title=Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion |journal=Hepatology |volume=38 |issue= 3 |pages= 692–702 |year= 2003 |pmid= 12939596 |doi= 10.1053/jhep.2003.50351 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Coll O, Colell A, García-Ruiz C, ''et al.'' |title=Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion. |journal=Hepatology |volume=38 |issue= 3 |pages= 692-702 |year= 2003 |pmid= 12939596 |doi= 10.1053/jhep.2003.50351 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Kabe Y, Ohmori M, Shinouchi K, etal |title=Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier |journal=J. Biol. Chem. |volume=281 |issue= 42 |pages= 31729–35 |year= 2006 |pmid= 16920706 |doi= 10.1074/jbc.M604729200 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Kabe Y, Ohmori M, Shinouchi K, ''et al.'' |title=Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier. |journal=J. Biol. Chem. |volume=281 |issue= 42 |pages= 31729-35 |year= 2006 |pmid= 16920706 |doi= 10.1074/jbc.M604729200 }}
}}
}}
{{refend}}
{{refend}}


{{membrane-protein-stub}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
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[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
{{WikiDoc Sources}}
 
 
{{membrane-protein-stub}}

Revision as of 06:29, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.[1][2][3]


See also

References

  1. Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet. 83 (3–4): 256–7. doi:10.1159/000015198. PMID 10072597.
  2. Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID 1457818.
  3. "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".

Further reading