Celiac disease epidemiology and demographics: Difference between revisions
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*The prevalence of celiac disease is approximately 0.71 % or 710 per 100,000 individuals in United States.<ref name="pmid22850429">{{cite journal |vauthors=Rubio-Tapia A, Ludvigsson JF, Brantner TL, Murray JA, Everhart JE |title=The prevalence of celiac disease in the United States |journal=Am. J. Gastroenterol. |volume=107 |issue=10 |pages=1538–44; quiz 1537, 1545 |year=2012 |pmid=22850429 |doi=10.1038/ajg.2012.219 |url=}}</ref> | *The prevalence of celiac disease is approximately 0.71 % or 710 per 100,000 individuals in United States.<ref name="pmid22850429">{{cite journal |vauthors=Rubio-Tapia A, Ludvigsson JF, Brantner TL, Murray JA, Everhart JE |title=The prevalence of celiac disease in the United States |journal=Am. J. Gastroenterol. |volume=107 |issue=10 |pages=1538–44; quiz 1537, 1545 |year=2012 |pmid=22850429 |doi=10.1038/ajg.2012.219 |url=}}</ref> | ||
*The overall prevalence of Celiac disease has been increasing in United States from 0.17% in 1988 to 0.44% in 2012.<ref name="pmid25665935">{{cite journal |vauthors=Choung RS, Ditah IC, Nadeau AM, Rubio-Tapia A, Marietta EV, Brantner TL, Camilleri MJ, Rajkumar SV, Landgren O, Everhart JE, Murray JA |title=Trends and racial/ethnic disparities in gluten-sensitive problems in the United States: findings from the National Health and Nutrition Examination Surveys from 1988 to 2012 |journal=Am. J. Gastroenterol. |volume=110 |issue=3 |pages=455–61 |year=2015 |pmid=25665935 |doi=10.1038/ajg.2015.8 |url=}}</ref> | *The overall prevalence of Celiac disease has been increasing in United States from 0.17% in 1988 to 0.44% in 2012.<ref name="pmid25665935">{{cite journal |vauthors=Choung RS, Ditah IC, Nadeau AM, Rubio-Tapia A, Marietta EV, Brantner TL, Camilleri MJ, Rajkumar SV, Landgren O, Everhart JE, Murray JA |title=Trends and racial/ethnic disparities in gluten-sensitive problems in the United States: findings from the National Health and Nutrition Examination Surveys from 1988 to 2012 |journal=Am. J. Gastroenterol. |volume=110 |issue=3 |pages=455–61 |year=2015 |pmid=25665935 |doi=10.1038/ajg.2015.8 |url=}}</ref> | ||
*Worldwide, the prevalence of celiac disease is estimated to be 0.5% - 1% of world population. | |||
*The risk for celiac disease is higher for people with diabetes, autoimmune disorder and relatives with celiac disease individuals because of shared HLA typing. | |||
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | *In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | ||
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually. | *The prevalence of [disease/malignancy] is estimated to be [number] cases annually. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Celiac Disease is more prevalent than previously thought. Prevalence has been shown to be as high as 1:250 [1] ). The prevalence may be as high as 1:133 in the general population.
Epidemiology and Demographics
Prevalence
The prevalence of clinically diagnosed disease (symptoms prompting diagnostic testing) is 0.05–0.27% in various studies. However, population studies from parts of Europe, India, South America, Australasia and the USA (using serology and biopsy) indicate that the prevalence may be between 0.33 and 1.06% in children (5.66% in one study of Saharawi children[2]) and 0.18–1.2% in adults. People of African, Japanese and Chinese descent are rarely diagnosed; this reflects a much lower prevalence of the genetic risk factors. Population studies also indicate that a large proportion of coeliacs remain undiagnosed; this is due to many clinicians being unfamiliar with the condition.[3]
A large multicentre study in the U.S. found a prevalence of 0.75% in not-at-risk groups, rising to 1.8% in symptomatic patients, 2.6% in second-degree relatives of a patient with coeliac disease and 4.5% in first-degree relatives. This profile is similar to the prevalence in Europe.[4]
Incidence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The prevalence of celiac disease is approximately 0.71 % or 710 per 100,000 individuals in United States.[5]
- The overall prevalence of Celiac disease has been increasing in United States from 0.17% in 1988 to 0.44% in 2012.[6]
- Worldwide, the prevalence of celiac disease is estimated to be 0.5% - 1% of world population.
- The risk for celiac disease is higher for people with diabetes, autoimmune disorder and relatives with celiac disease individuals because of shared HLA typing.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
among non-Hispanic whites (1.0%) than among non-Hispanic blacks (0.2%) and Hispanics (0.3%)
Case-fatality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate of [number range]%.
- The case-fatality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ Detecting Celiac Disease in Your Patients", American Family Physician, Vol. 57/No. 5, Pruessner, Harold T., M.D. http://www.aafp.org/afp/980301ap/pruessn.html
- ↑ Catassi C, Rätsch I, Gandolfi L, Pratesi R, Fabiani E, El Asmar R, Frijia M, Bearzi I, Vizzoni L (1999). "Why is coeliac disease endemic in the people of the Sahara?". Lancet. 354 (9179): 647–8. PMID 10466670.
- ↑ Zipser R, Farid M, Baisch D, Patel B, Patel D (2005). "Physician awareness of celiac disease: a need for further education". J Gen Intern Med. 20 (7): 644–6. PMID 16050861.
- ↑ Fasano A, Berti I, Gerarduzzi T, Not T, Colletti R, Drago S, Elitsur Y, Green P, Guandalini S, Hill I, Pietzak M, Ventura A, Thorpe M, Kryszak D, Fornaroli F, Wasserman S, Murray J, Horvath K (2003). "Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study". Archives of Internal Medicine. 163 (3): 286–92. PMID 12578508.
- ↑ Rubio-Tapia A, Ludvigsson JF, Brantner TL, Murray JA, Everhart JE (2012). "The prevalence of celiac disease in the United States". Am. J. Gastroenterol. 107 (10): 1538–44, quiz 1537, 1545. doi:10.1038/ajg.2012.219. PMID 22850429.
- ↑ Choung RS, Ditah IC, Nadeau AM, Rubio-Tapia A, Marietta EV, Brantner TL, Camilleri MJ, Rajkumar SV, Landgren O, Everhart JE, Murray JA (2015). "Trends and racial/ethnic disparities in gluten-sensitive problems in the United States: findings from the National Health and Nutrition Examination Surveys from 1988 to 2012". Am. J. Gastroenterol. 110 (3): 455–61. doi:10.1038/ajg.2015.8. PMID 25665935.