Delayed puberty causes: Difference between revisions
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===Causes in Alphabetical Order=== | ===Causes in Alphabetical Order=== | ||
List the causes of the disease in alphabetical order.{{columns-list|3| | List the causes of the disease in alphabetical order.{{columns-list|3| | ||
* | * [[5-alpha reductase deficiency]] | ||
* | * 17,20-[[lyase]] deficiency | ||
* | * [[AIDS]] | ||
* | * [[Androgen insensitivity]] | ||
* | * [[Anorexia nervosa]] | ||
* | * [[Asthma]] | ||
* | * [[Astrocytoma]] | ||
* | * Autoimmune oophiritis | ||
* | * Autoimmune [[orchitis]] | ||
* | * [[Bardet-Biedl syndrome]] | ||
* [[Bulimia]] | |||
* [[Celiac disease]] | |||
* [[CHARGE syndrome]] | |||
* [[Chemotherapy]] | |||
* [[CHD7|Chromodomain helicase DNA-binding protein 7 (CHD7)]] | |||
* [[Chronic renal disease]] | |||
* Congenital [[hypopituitarism]] | |||
* [[Lipoid congenital adrenal hyperplasia|Congenital lipoid adrenal hyperplasia]] | |||
* [[Coxsackie virus]] | |||
* [[Craniopharyngioma]] | |||
* [[Cryptorchidism]] | |||
* [[Cushing syndrome]] | |||
* [[Cystic fibrosis]] | |||
* [[Diabetes mellitus]] | |||
* [[DAX1|DSS-AHC on the X-chromosome 1 (DAX1)]] | |||
* Early B-cell factor 2 (EBF2) | |||
* [[Estrogen receptor alpha|Estrogen receptor α (ESR1)]] | |||
* Excessive [[exercise]] | |||
* [[Fibroblast growth factor 8|Fibroblast growth factor 8 (FGF8)]] | |||
* [[Fibroblast growth factor receptor 1|Fibroblast growth factor receptor 1 (FGFR1)]] | |||
* [[Fragile X|Fragile X premutation]] | |||
* [[Galactosemia]] | |||
* [[Gaucher disease]] | |||
* [[Germinoma]] | |||
* [[Glioma]] | |||
* [[Gonadal dysgenesis]] | |||
* [[Gonadotropin releasing hormone|Gonadotropin releasing hormone (GnRH1)]] | |||
* [[Gonadotropin releasing hormone]] receptor (GnRHR) | |||
* [[Growth hormone deficiency]] | |||
* [[Hemosiderosis]] | |||
* [[Heparan sulfate]] 6-O-sulphotransferase 1 (HS6ST1) | |||
* [[HESX1|Homeobox gene 1 (HESX1)]] | |||
* [[Hyperprolactinemia]] | |||
* Hypothalamus-pituitary-gonadal (HPG) Axis development disorder | |||
* [[Hypothyroidism]] | |||
* [[Inflammatory bowel disease]] | |||
* [[Isolated hypogonadotropic hypogonadism]] | |||
* [[Juvenile rheumatoid arthritis]] | |||
* [[Kallmann syndrome]] | |||
* [[KAL1 gene|Kallmann syndrome 1 (KAL1) gene]] | |||
* [[Kisspeptin|Kisspeptin system (KISS1R and KISS1)]] | |||
* [[Langerhans cell histiocytosis]] | |||
* [[Leptin|Leptin (LEP)]] | |||
* [[Leptin receptor|Leptin receptor (LEPR)]] | |||
* [[LHX3|LIM homeobox gene 3 (LHX3)]] | |||
* Makorin RING-finger protein 3 (MKRN3) | |||
* [[Malnutrition]] | |||
* [[Mumps]] | |||
* Nasal embryonic LH-releasing hormone factor (NELF) | |||
* [[Noonan syndrome]] and related disorders | |||
* [[Obesity]] and [[hypogonadotropic hypogonadism]] | |||
* Post [[central nervous system]] infection | |||
* [[Prader-Willi syndrome]] | |||
* [[Prokineticin|Prokineticin 2 (PROK2)]] | |||
* [[Prokineticin receptor 2|Prokineticin 2 receptor (PROKR2)]] | |||
* [[Prolactinoma]] | |||
* Proprotein convrtase 1 (PC1) | |||
* [[PROP1|PROP paired-like homeobox 1 (PROP1)]] | |||
* [[Radiation therapy]] | |||
* [[Rathke pouch]] cyst | |||
* [[Septo-optic dysplasia]] | |||
* [[Sertoli cell]] only syndrome (Del Castillo syndrome) | |||
* [[Sickle cell disease]] | |||
* [[SF1 (gene)|Steroidogenic factor 1 (SF1)]] | |||
* [[Tachykinin|Tachykinin 3 (TAC3)]] | |||
* [[Tachykinin receptor 3|Tachykinin 3 receptor (TACR3)]] | |||
* [[Testicular torsion]] | |||
* Testicular [[trauma]] | |||
* [[Thalassemia]] | |||
* [[Turner syndrome]] | |||
* [[Vanishing testes syndrome]] | |||
}} | }} | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 13:42, 5 September 2017
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Delayed puberty Microchapters |
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Risk calculators and risk factors for Delayed puberty causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Delayed puberty may be caused by endocrine or genetic causes. The most common endocrine causes of delayed puberty is hypothalamus-pituitary-gonadal (HPG) axis disorders. The most common genetic causes of delayed puberty is Kallmann syndrome. There are various genes that may be related to delayed puberty, among which the kisspeptin system genes (KISS1 and KISS1R) are the most important genes.
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of delayed puberty, however complications resulting from untreated delayed puberty are common.
Common Causes
Delayed puberty may be caused by:
- Mumps
- Cryptorchidism
- Turner syndrome
- Testicular trauma
- Testicular torsion
- Sickle cell disease
- Thalassemia
- Kallmann syndrome
- Isolated hypogonadotropic hypogonadism
- Hypothalamus-pituitary-gonadal (HPG) Axis development disorder
- Obesity and hypogonadotropic hypogonadism
- Cystic fibrosis
- Asthma
- Inflammatory bowel disease
- Celiac disease
- Diabetes mellitus
- Excessive exercise
- Malnutrition
Less Common Causes
Less common causes of disease name are including:
- Noonan syndrome and related disorders
- Fragile X premutation
- Gonadal dysgenesis
- Vanishing testes syndrome
- Coxsackie virus
- Galactosemia
- Autoimmune oophiritis
- Autoimmune orchitis
- 5-alpha reductase deficiency
- 17,20-lyase deficiency
- Congenital lipoid adrenal hyperplasia
- Androgen insensitivity
- Sertoli cell only syndrome (Del Castillo syndrome)
- Astrocytoma
- Germinoma
- Glioma
- Craniopharyngioma
- Prolactinoma
- Langerhans cell histiocytosis
- Rathke pouch cyst
- Prader-Willi syndrome
- Bardet-Biedl syndrome
- CHARGE syndrome
- Gaucher disease
- Post central nervous system infection
- Septo-optic dysplasia
- Congenital hypopituitarism
- Chemotherapy
- Radiation therapy
- Juvenile rheumatoid arthritis
- Anorexia nervosa
- Bulimia
- Hemosiderosis
- Chronic renal disease
- AIDS
- Hypothyroidism
- Hyperprolactinemia
- Growth hormone deficiency
- Cushing syndrome
Genetic Causes
Delayed puberty is caused by a mutation in the following genes:
- Kisspeptin system (KISS1R and KISS1)
- Kallmann syndrome 1 (KAL1)
- Fibroblast growth factor receptor 1 (FGFR1)
- Fibroblast growth factor 8 (FGF8)
- Heparan sulfate 6-O-sulphotransferase 1 (HS6ST1)
- Prokineticin 2 (PROK2)
- Prokineticin 2 receptor (PROKR2)
- Tachykinin 3 (TAC3)
- Tachykinin 3 receptor (TACR3)
- Gonadotropin releasing hormone (GnRH1)
- Gonadotropin releasing hormone receptor (GnRHR)
- Chromodomain helicase DNA-binding protein 7 (CHD7)
- Nasal embryonic LH-releasing hormone factor (NELF)
- Early B-cell factor 2 (EBF2)
- DSS-AHC on the X-chromosome 1 (DAX1)
- Steroidogenic factor 1 (SF1)
- Homeobox gene 1 (HESX1)
- LIM homeobox gene 3 (LHX3)
- PROP paired-like homeobox 1 (PROP1)
- Leptin (LEP)
- Leptin receptor (LEPR)
- Proprotein convrtase 1 (PC1)
- Makorin RING-finger protein 3 (MKRN3)
- Estrogen receptor α (ESR1)
Causes by Organ System
Causes in Alphabetical Order
List the causes of the disease in alphabetical order.
The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
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