Airway management: Difference between revisions

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==Overview==
==Overview==
In [[cardiopulmonary resuscitation]], [[anaesthesia]], [[emergency medicine]], [[intensive care medicine]] and [[first aid]], ''airway management'' is the process of ensuring that there is an open pathway between a patient’s [[lung]]s and the outside world, an the lungs are safe from [[Pulmonary aspiration|aspiration]]. Airway loss is a major cause of preventable prehospital death in trauma patients. Trauma airway management is complicated because of associated pathology and suboptimal intubating conditions, and also because complete preintubation evaluation and planning is rarely possible. Furthermore, trauma patients are at increased risk for hypoxia, airway obstruction, hypoventilation, hypotension, and aspiration.
''Airway management'' is the process of ensuring that there is an open pathway between a patient’s [[lung]]s and the outside world, and the [[lungs]] are safe from [[Pulmonary aspiration|aspiration]]. [[Airway]] loss is a major cause of preventable prehospital death in [[trauma]] patients. Airway management complications are common, especially in [[trauma]] patients because of associated [[pathology]], lack of complete evaluation before [[intubation]], unanticipated difficulty during ventilation and [[intubation]]. Additionally, [[trauma]] [[patients]] are at increased risk of [[airway obstruction]], aspiration, [[hypoxia]] and [[hypotension]], and  [[vital sign|other unstable vital]]  The providers must have skillset related to working with a variety of tools and techniques used in airway management and knowledge of the important [[anatomical]], [[physiological]], and [[pathological]] features related to the airway. They also should know the differences between the adult versus [[pediatric]] and [[neonatal]] airways as these [[anatomical]] and physiological differences are critical, impactful on patients lives and knowing these leads to effective control and management of the [[airway]]. Some of the indications for managing the [[airway]] in patients include [[respiratory failure]], altered sensorium([[Glasgow Coma Scale]] less than or equal to 8), rapid deterioration of [[mental status]], [[airway]] injury or compromise, injuries causing a high risk for [[aspiration]]-which includes all penetrating injuries to the [[abdomen]] or [[chest wall]]. Inadequate [[airway]] management may lead to [[cardiovascular]] arrest and compromise life-saving interventions in a [[trauma]] patient. Several [[airway]] control devices and techniques are available to assist [[healthcare]] providers in order to maintain the airway by [[ventilation]] and [[oxygenation]]. These include [[bag valve mask]] ([[Bag valve mask|BVM]]) [[ventilation]], direct [[laryngoscopy]] with [[endotracheal intubation]] (ETI) and adjunct [[Supraglottitis|supraglottic]] [[airway]] devices such as the [[laryngeal]] mask airway.
 
==Functional anatomy of the upper airway==
For a successful approach to [[airway]] management, [[health care providers]] must have knowledge of important [[anatomical]], [[physiological]], and [[pathological]] features related to the airway as well as knowledge of the various equipment and methods that can be utilized for this purpose. Also, the difference between airway management in adults, [[pediatrics]], and [[neonates]] is very critical.<ref name="pmid3056703">{{cite journal |vauthors=Morris IR |title=Functional anatomy of the upper airway |journal=Emerg. Med. Clin. North Am. |volume=6 |issue=4 |pages=639–69 |date=November 1988 |pmid=3056703 |doi= |url=}}</ref>
 
*The [[upper airway]] is consists of the [[pharynx]] and [[nasal]] cavities, the [[larynx]] and [[trachea]] may be included, and the [[oral cavity]] provides an alternate air entry into the [[respiratory system]].
*The nose is a bony and [[cartilage|cartilaginous]] structure attached to the facial [[skeleton]] and is divided into the two [[nasal]] cavities. The nose functions as a heater and humidifier of inspired air, it is also helps in [[phonation]] and [[vocal resonation]] and houses the [[olfactory]] receptors. The [[paranasal sinuses]] drain into the nasal cavities.
*An [[endotracheal tube]] passes through the [[nose]] or mouth into the [[trachea]] to protect the [[airway]] and achieve positive-pressure [[ventilation]]. The mouth opens posteriorly into the [[oropharynx]] and becomes part of the [[gastrointestinal system]], helps the [[digestion]] and also plays a role as an alternate pathway for [[respiration]]. It is also involved in [[phonation]].
*[[Orotracheal intubation]] can be used as an alternative to [[nasal]] [[intubation]] to achieve [[airway]] protection and maintain [[ventilation]]; but depending upon the condition of the [[patient]] and difficulty due to [[anatomical]] shape of [[upper airway]], this route may not be doable, for instance in supine unconscious persons, the backward movement of the [[tongue]] and lower [[jaw]] may cause [[airway obstruction]] and performing [[orotracheal intubation]] may not be the optimal way of managing airway.
*The [[pharynx]] is a membrane-lined cavity behind the [[mouth]] and [[nose]], extends from the base of the [[skull]] to the [[cricoid cartilage]] at the level of sixth [[cervical vertebrae]] which is an entrance to the [[esophagus]]. [[Anterior]]<nowiki/>ly it opens into the [[nasal cavity]], the [[mouth]], and the [[larynx]], which divide it into the naso-, oro-, and [[laryngopharynx]], respectively. The [[pharynx]] is involved with the act of [[swallowing]].
*The [[larynx]] consists of [[Cartilages of the larynx|cartilages]] and fibro-elastic membranes covered by a sheet of [[muscles]] and [[mucous membrane]]. It functions as an open valve in [[respiration]], helps in [[phonation]], and [[swallowing]]. The [[larynx]] extends from its entrance which is formed by the [[Aryepiglottic fold|aryepiglottic folds]], to the lower border of the [[cricoid cartilage]] till the tip of the [[epiglottis]], and bulges [[posterior]]<nowiki/>ly into the [[laryngopharynx]].
*The trachea is formed by U-shaped [[cartilaginous]] rings in anterior and [[trachealis muscle]] in [[posterior]], it extends from the lower edge of the [[cricoid cartilage]] to the [[carina]] where it divides into the [[mainstem bronchus]]. In order to place [[endotracheal tube]] in proper way, tip of the tube should be at mid [[Tracheal bronchus|tracheal]] level.


In nearly all circumstances airway management is the highest priority for clinical care. This is because if there is no airway, there can be no breathing, hence no oxygenation of blood and therefore circulation (and hence all the other vital body processes) will soon cease. Getting oxygen to the lungs is the first step in almost all clinical treatments. The ‘A’ is for ‘airway’ in the ‘ABC’ of [[cardiopulmonary resuscitation]].


==Functional anatomy of the upper airway==
[[File:UpperRespiratorySystem.png|400px|thumb|left|upper airway system[https://commons.wikimedia.org/wiki/File:Blausen_0872_UpperRespiratorySystem.pngBlausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436.]]]<br style="clear:left" />
For successful aproach to airway management, health care providers must have knowledge of important anatomical, physiological, and pathological features related to the airway as well as knowledge of the various equipments and methods that can be utilized for this purpose. Also the difference of airway management in adults, pediatrics and neonates is very critical. 
* Anatomically, the upper airway consists of the pharynx and nasal cavities, functionally, the larynx and trachea may be included, and the oral cavity provides an alternate entrance to the respiratory passages.  
* The nose is a pyramidal structure composed of bone and cartilage attached to the facial skeleton, and is divided by a midline septum into the two nasal cavities. The nose functions as a heater and humidifier of inspired gas, a voice resonator, and houses the olfactory receptors. The paranasal sinuses drain into the nasal cavities.
* An endotracheal tube may be passed through the nose into the trachea when necessary to protect the airway and achieve positive-pressure ventilation. The mouth opens posteriorly into the oropharynx and forms the entrance to the digestive tract as well as an alternate pathway for respiration. It is also involved in phonation.
* Orotracheal intubation can be used as an alternative to nasal intubation to achieve airway protection and ventilation when necessary; however, variations in upper airway anatomy may make this technique difficult. In supine unconscious persons, backward movement of the tongue and lower jaw may cause airway obstruction.
* The pharynx is a U-shaped fibromuscular tube extending from the base of the skull to the cricoid cartilage at the entrance to the esophagus. Anteriorly it opens into the nasal cavity, the mouth, and the larynx, which divide it into the naso-, oro-, and laryngopharynx, respectively. The pharynx thus forms a common aerodigestive tract and is intimately involved with the act of swallowing.  
* The larynx consists of a framework of cartilages and fibroelastic membranes covered by a sheet of muscles and lined with mucous membrane. It evolved as a protective valve mechanism at the upper end of the lower airway necessitated by an unusual crossover between the airway and alimentary canal. It functions as an open valve in respiration, a partially closed valve in phonation, and as a closed valve protecting against aspiration during swallowing. The larynx extends from its oblique entrance formed by the aryepiglottic folds, the tip of the epiglottis, and the posterior commissure to the lower border of the cricoid cartilage and bulges posteriorly into the laryngopharynx.
* The trachea extends from the lower edge of the cricoid cartilage to the carina where it divides into the mainstem bronchi. It is formed by U-shaped cartilaginous rings anteriorly and is closed posteriorly by the trachealis muscle. A properly placed endotracheal tube should have its tip at about midtracheal level


==Recommendations for evaluation of airway==
==Recommendations for evaluation of airway==
:The basic approach in airway management in emergency setting includes assuring airway patency, protection from aspiration, and providing adequate oxygenation and ventilation. Following are steps that must be considered prior to conducting airway management, these are include:  
The basic approach in airway management in the [[emergency]] setting includes:<ref name="RosenbergPhero2014">{{cite journal|last1=Rosenberg|first1=M. B|last2=Phero|first2=J. C|last3=Becker|first3=D. E|title=Essentials of Airway Management, Oxygenation, and Ventilation: Part 2: Advanced Airway Devices: Supraglottic Airways|journal=Anesthesia Progress|volume=61|issue=3|year=2014|pages=113–118|issn=0003-3006|doi=10.2344/0003-3006-61.3.113}}</ref>
:*'''History:''' An airway history should be conducted, whenever it is feasible, before the initiation of anesthetic care and airway management in all patients to detect medical, surgical, and anesthetic factors that may indicate the presence of a difficult airway. Examination of previous anesthetic records, if available in a timely manner, may yield useful information about airway management.


:*'''Physical Examination:''' An airway physical examination should be conducted before intiation of airway management,The intent of this examination is to detect physical characteristics that may indicate the presence of a difficult airway.
:*Protection from [[aspiration]] and [[pneumonia]] related to that.
:*Providing adequate [[ventilation]] and [[oxygenation]].


:*'''Additional Evaluation'''. Additional evaluation may be indicated in some patients to characterize the likelihood or nature
Following are steps that must be considered prior to conducting airway management, these include:
of the anticipated airway difficulty. Certain diagnostic tests (e.g., radiography, computed tomography scans, fluoroscopy) can identify a variety of acquired or congenital features in patients with difficult airways
==Techniques for airway management prior to hospital arrival==
The decision about whether an airway intervention is required or not is crucial for patients survival and depends on first responders skills and qucik assessment and decision. These crucial steps requires techniques which is used universally in order to manage patient's airway, followings are initial evaluation and methods which had been developed to assist patient's ventilation and keep the airway patent, these techniques include:<ref name="BernhardBehrens2018">{{cite journal|last1=Bernhard|first1=M.|last2=Behrens|first2=N. H.|last3=Wnent|first3=J.|last4=Seewald|first4=S.|last5=Brenner|first5=S.|last6=Jantzen|first6=T.|last7=Bohn|first7=A.|last8=Gräsner|first8=J. T.|last9=Fischer|first9=M.|title=Out-of-hospital airway management during manual compression or automated chest compression devices|journal=Der Anaesthesist|volume=67|issue=2|year=2018|pages=109–117|issn=0003-2417|doi=10.1007/s00101-017-0401-6}}</ref>
* '''Spontaneous breathing:''' Spontaneous breathing remains a viable option for airway management when a provider is confronted with an awake patient possessing a patent airway. Assistance for spontaneous ventilation can be performed through the placement of a nasal or oral airway. Oxygenation can be improved with the supplementation of oxygen via nasal cannula, simple face mask, or nonrebreather face mask. Unfortunately, the maximally achieved FiO2 is often over estimated by care providers and hypoventilation resulting in hypercapnia cannot be normalized with increase oxygen supply.
:*'''Mouth-to-Mouth ventilation:''' Mouth-to-mouth or mouth-to-nose ventilation is still a recognized management technique for prehospital airway management. However, this modality has fallen out of favor recently with the increasing support of “hands-only” CPR. Proper face masks should be utilized if they are available.


:*'''Bag-mask ventilation:''' It is a standard initial approach to airway management in the prehospital and hospital settings.
:*'''History:''' An [[airway]] [[history]] should be conducted whenever it is possible before airway management in all [[patients]] to detect medical, [[surgical]], and [[anesthetic]] factors that may indicate the presence of a difficult [[airway]]. A detailed review of previous [[anesthetic]] records, if available, may provide useful information about airway management.
:*Proper preoxygenation prior to intubation provides patients with improved oxygenation and increases time to hypoxemia.
:*BMV can be applied as a sole practitioner or in conjunction with a second care provider.
:*BMV can also occur during spontaneous respirations as a pressure support method for patients with depressed tidal volumes and inadequate ventilation.
:*This is similar to the use of CPAP or BiPAP to assist patients who are spontaneously breathing but are not adequately oxygenating or ventilating.


:*'''Oropharyngeal and nasopharyngeal airways:'''  
:*'''Physical Examination:''' An airway [[physical examination]] should be conducted before the initiation of airway management. The goal of [[physical examination]] is to detect physical characteristics that may indicate the presence of a difficult airway because an unsuccessful  [[upper airway|airway]] management is associated with increase in [[mortality]] and [[morbidity]].
:*This is used as an adjunct device for spontaneous or assisted ventilation.
:*Oropharyngeal and nasopharyngeal airways are frequently utilized by prehospital care providers to improve oxygenation and ventilation.
:*These devices are frequently used to temporize until a more definitive airway is obtained, and there are several circumstances that prohibit their placement (severe head or facial injuries).


:*'''Supraglottic airway devices:''' Supraglottic airway (SGA) device placement is very useful to keep the airways open, it has advantages in comparison with Endotracheal tube intubation, or other methods these are include:
:*'''Additional Evaluation:''' Additional evaluation may be indicated in some [[patients]] to characterize the likelihood or nature of the anticipated difficult airway. Certain diagnostic tests (e.g., [[radiography]], [[computed tomography]] scans, [[fluoroscopy]]) can identify a variety of acquired or congenital features in patients with difficult airways
:**Requires less training than ETI.  
:**It is less invasive than ETI.
:**For care providers not sufficiently trained in ETI these devices can offer better ventilation during transport than BMV alone.  
:**SGAs can be used as a backup tool for failed intubation in accordance with the difficult airway algorithm by the American Society of Anesthesiology (ASA).


:*'''Endotracheal intubation:''' It is the gold standard for definitive airway management in the prehospital setting. ETI advantages are include:
==Techniques for airway management==
:**It allows for positive pressure ventilation, positive end-expiratory pressure (PEEP), positive pressure recruitment maneuvers, and protection from aspiration.
The decision about whether an airway intervention is required or not is crucial for patient's [[Survival rate|survival]] and depends on first responders skills and quick assessment and decision. These crucial steps requires techniques which are used universally in order to manage [[patient]]'s airway. Following are initial evaluation methods which had been developed to assist patient's [[ventilation]] and keep the [[airway]] patent, these techniques include:<ref name="RoychoudhuryJose2016">{{cite journal|last1=Roychoudhury|first1=Ajoy|last2=Jose|first2=Anson|last3=Nagori|first3=ShakilAhmed|last4=Agarwal|first4=Bhaskar|last5=Bhutia|first5=Ongkila|title=Management of maxillofacial trauma in emergency: An update of challenges and controversies|journal=Journal of Emergencies, Trauma, and Shock|volume=9|issue=2|year=2016|pages=73|issn=0974-2700|doi=10.4103/0974-2700.179456}}</ref><ref name="pmid18946431">{{cite journal |vauthors=Agrò FE, Cataldo R, Mattei A |title=New devices and techniques for airway management |journal=Minerva Anestesiol |volume=75 |issue=3 |pages=141–9 |date=March 2009 |pmid=18946431 |doi= |url=}}</ref><ref name="pmid29560073">{{cite journal |vauthors=Gleason JM, Christian BR, Barton ED |title=Nasal Cannula Apneic Oxygenation Prevents Desaturation During Endotracheal Intubation: An Integrative Literature Review |journal=West J Emerg Med |volume=19 |issue=2 |pages=403–411 |date=March 2018 |pmid=29560073 |pmc=5851518 |doi=10.5811/westjem.2017.12.34699 |url=}}</ref><ref name="LawBroemling2013">{{cite journal|last1=Law|first1=J. Adam|last2=Broemling|first2=Natasha|last3=Cooper|first3=Richard M.|last4=Drolet|first4=Pierre|last5=Duggan|first5=Laura V.|last6=Griesdale|first6=Donald E.|last7=Hung|first7=Orlando R.|last8=Jones|first8=Philip M.|last9=Kovacs|first9=George|last10=Massey|first10=Simon|last11=Morris|first11=Ian R.|last12=Mullen|first12=Timothy|last13=Murphy|first13=Michael F.|last14=Preston|first14=Roanne|last15=Naik|first15=Viren N.|last16=Scott|first16=Jeanette|last17=Stacey|first17=Shean|last18=Turkstra|first18=Timothy P.|last19=Wong|first19=David T.|title=The difficult airway with recommendations for management – Part 1 – Difficult tracheal intubation encountered in an unconscious/induced patient|journal=Canadian Journal of Anesthesia/Journal canadien d'anesthésie|volume=60|issue=11|year=2013|pages=1089–1118|issn=0832-610X|doi=10.1007/s12630-013-0019-3}}</ref><ref name="OkuboGibo2017">{{cite journal|last1=Okubo|first1=Masashi|last2=Gibo|first2=Koichiro|last3=Hagiwara|first3=Yusuke|last4=Nakayama|first4=Yukiko|last5=Hasegawa|first5=Kohei|title=The effectiveness of rapid sequence intubation (RSI) versus non-RSI in emergency department: an analysis of multicenter prospective observational study|journal=International Journal of Emergency Medicine|volume=10|issue=1|year=2017|issn=1865-1372|doi=10.1186/s12245-017-0129-8}}</ref>


:*'''Rapid sequence intubation versus no-medication intubation'''
*'''Spontaneous breathing:''' When a provider is confronted with an awake [[patient]] having a patent airway. Spontaneous ventilation can be assisted through the placement of a nasal or oral airway. [[Oxygenation]] can be improved by giving [[oxygen]] via nasal [[cannula]], simple [[face mask]], or nonrebreather face mask. Unfortunately, the maximally achieved [[FiO2]] is often overestimated by care providers and [[hypoventilation]] resulting in [[hypercapnia]] cannot be normalized with increase in [[oxygen]] supply.
Pharmacologic muscle paralysis relaxes the pharyngeal and facial musculature and results in improved intubation conditions. Rapid sequence intubation (RSI) techniques incorporate pharmacologic muscle relaxation and are utilized by anesthesiologists and emergency medicine physicians. However, one drawback to these techniques is the elimination of a patient's ability to breathe spontaneously if the intubation fails. Yet many providers conversely argue that optimal intubating conditions should be achieved prior to attempted intubation in the prehospital setting. The reason for this is that prehospital airway intervention is frequently time sensitive due to trauma, cardiac arrest, hypoxemia, or aspiration risk.
*'''Mouth-to-Mouth ventilation:''' Mouth-to-mouth or mouth-to-nose ventilation is a useful management technique, however, because of the risk of [[infection]] transmission it is recommended by American heart association that health care providers do "Hands-only" [[CPR]]. Proper face masks should be utilized if they are available.
*'''Bag-mask ventilation:''' It is a standard initial approach to airway management in the prehospital and [[hospital]] settings.


:*Proper preoxygenation prior to [[intubation]] and [[anesthetic]] induction provides patients with improved [[oxygenation]] and increases the time to [[hypoxemia]].
:*Bag-mask [[ventilation]] is a basic essential technique when [[endotracheal tube]] [[intubation]] is difficult, it assists for rapid [[ventilation]] and [[oxygenation]] in patients.
:*Bag-mask [[ventilation]] can be achieved by a single practitioner alone or side by side with a second care provider in an [[Operating room|emergency room or an operating room]]
:*Bag mask [[ventilation]] can also be utilized as a pressure support during spontaneous [[respiration]] in patients with decre<nowiki/>ased [[tidal volume]]<nowiki/>s and insufficient [[ventilation]], very similar to the use of [[CPAP]] or [[BiPAP]] to assist [[patients]] who are spontaneously [[breathing]] but are not adequately ventilating or oxygenating.
*'''Oropharyngeal and nasopharyngeal airways:'''
:*This is used as an adjunct device for spontaneous or [[assisted ventilation]].
:*[[Oropharyngeal]] and [[nasopharyngeal airway]]<nowiki/>s are frequently utilized by prehospital care providers to improve [[oxygenation]] and [[ventilation]].
:*These devices are frequently used until a more definitive [[airway]] is obtained, and there are several circumstances that prohibit their placement (severe head or [[facial]] injuries).
*'''Supraglottic airway devices:''' [[Supraglottic laryngeal cancer|Supraglottic]] airway (SGA) device placement is very useful to keep the [[airway]]<nowiki/>s open, it has advantages in comparison with [[endotracheal tube]] intubation, or other methods, these advantages include:<ref name="pmid27537593">{{cite journal |vauthors=Park SK, Ko G, Choi GJ, Ahn EJ, Kang H |title=Comparison between supraglottic airway devices and endotracheal tubes in patients undergoing laparoscopic surgery: A systematic review and meta-analysis |journal=Medicine (Baltimore) |volume=95 |issue=33 |pages=e4598 |date=August 2016 |pmid=27537593 |doi=10.1097/MD.0000000000004598 |url=}}</ref>
:*They act as a niche between [[bag and mask ventilation]] and endotracheal [[intubation]].
:*Requires less training than [[ETI]].
:*It is less invasive than [[ETI]].
:*It can offer better [[ventilation]] during transport than bag-mask [[ventilation]] alone.
:**[[Supraglottitis|Supraglottic]] airway devices can be used as an alternative tool in cases of failed [[intubation]].
*'''[[Endotracheal intubation]]:''' It is the gold standard for definitive airway management in the prehospital setting, and also hospital setting. It allows for positive pressure [[ventilation]], [[positive end-expiratory pressure]] (PEEP), positive pressure recruitment maneuvers, and protection from [[aspiration]].
:*'''Mallampati classification for assessment of upper airway anatomical Balance:''' It is named after the Indian-born American [[anesthesiologist]] Seshagiri Mallampati, is used to predict the ease of [[endotracheal intubation]].The test assess the distance from the [[tongue]] base to the roof of the [[mouth]] visually. It is an indirect way of assessing how the airway and predicting the difficult intubation.
:*'''Modified Mallampati Scoring:'''
:**Class I: [[Soft palate]], [[uvula]], [[fauces]], [[Pillars of the fauces|pillars]] visible.
:**Class II: [[Soft palate]], a major part of the [[uvula]], [[fauces]] visible.
:**Class III: [[Soft palate]], the base of [[uvula]] visible.
:**Class IV: Only [[hard palate]] visible.
:*'''[[Cormack-Lehane grading ]]on [[Direct laryngoscopy]]:''' This grading is used to predict the difficulty in [[intubation]] based on the structures visualised on [[laryngoscopy]]. The grade 2 was subdivided into 2a and 2b in the modified [[Cormack-Lehane classification]].
:*'''Modified [[Cormack-Lehane classification]]:'''
:**Class 1:Full view of [[glottis ]]is visible.
:**Class 2a:Partial view of [[glottis]] is visible.
:**Class 2b:Only posterior extremity of [[glottis]] or only [[arytenoid cartilages]] are seen.
:**Class 3:Only [[epiglottis]] ,but not [[glottis]] is seen.
:**Class 4:Neither of the [[glottis]] or [[epiglottis]] are seen.
<br />
*'''Rapid sequence intubation''':
:*[[Rapid sequence intubation]] ([[RSI|RSI)]] is a technique used for endotracheal [[intubation]] when the patient is at high risk of [[aspiration]]. For RSI to be performed, it requires two persons, first patient's lungs are preoxygenated with bag and mask . One person applies constant pressure on the [[cricoid cartilage]], occluding the [[esophagus]]. Sedative-hypnotic or an [[induction agent]] and a [[muscle relaxant]] is administered and patient's [[trachea]] is intubated, and [[cricoid pressure ]]is released after the cuff is inflated. Traditionally, [[thiopentone sodium]] and [[succinylcholine]] were used for [[RSI]], and it had an advantage that patient's airway will be relaxed and paralysed, facilitating the [[intubation] and if any unanticipated difficulty occurs, these drugs were short acting and the effect weans off quickly. There is a debate that optimal intubating conditions should be achieved first before trying to attempt [[intubation]] in the prehospital setting. Time is an important factor and critical in prehospital [[airway]] management of [[patients]], due to [[trauma]], [[cardiac arrest]], [[hypoxemia]], or [[aspiration]] risk. Administration of the [[Neuromuscular blocking agents|neuromuscular blocking agent]] is associated with a reduction in time from rapid sequence [[intubation]] administration to the end of [[intubation]] attempt.


[[File:Glidescope 02.jpg|400px|thumb|left|Photograph of an anesthesiologist using the Glidescope video laryngoscope to intubate the trachea of a morbidly obese elderly person with challenging airway anatomy[https://en.wikipedia.org/wiki/Airway_managementI (DiverDave (talk)) created this work entirely by myself. (Original uploaded on en.wikipedia)]]]<br style="clear:left" />
[[File:Glidescope 02.jpg|400px|thumb|left|Photograph of an anesthesiologist using the Glidescope video laryngoscope to intubate the trachea of a morbidly obese elderly person with challenging airway anatomy[https://en.wikipedia.org/wiki/Airway_managementI (DiverDave (talk)) created this work entirely by myself. (Original uploaded on en.wikipedia)]]]<br style="clear:left" />


==Manual Methods==
==Management of the Airway in Patients with Trauma==
===Head Tilt/ Chin Lift===
*[[Airway management]] includes maintaining a patent [[airway ]]by [[bag and mask ventilation]], using [[oroapharyngeal]] or[[ nasopharyngeal]]airways, endotracheal [[intubation]] and also management of the airway during [[extubation]] and after [[extubation]].
The simplest way of ensuring an open airway in an unconscious patient is to use a head tilt chin lift technique, thereby lifting the tongue from the back of the throat. This is taught on most [[first aid]] courses as the standard way of clearing an airway.
===[[Difficult airway]]===
*[[Difficult airway]] includes problems encountered during [[bag and mask ventilation]], like holding of [[face mask]] applying [[positive pressure ventilation]], problems with [[laryngoscopy]] and [[intubation]].
===Suspected Spinal Cord Injury===


===Jaw Thrust===
*In [[patients]] with suspected [[trauma]], extreme caution must be taken in aligning the [[head]] and [[neck]]. The [[cervical spine]] must be maintained in a neutral mid-line position, the exception to this is physical resistance.<ref name="ThiboutotNicole2009">{{cite journal|last1=Thiboutot|first1=François|last2=Nicole|first2=Pierre C.|last3=Trépanier|first3=Claude A.|last4=Turgeon|first4=Alexis F.|last5=Lessard|first5=Martin R.|title=Effect of manual in-line stabilization of the cervical spine in adults on the rate of difficult orotracheal intubation by direct laryngoscopy: a randomized controlled trial|journal=Canadian Journal of Anesthesia/Journal Canadien d'anesthésie|volume=56|issue=6|year=2009|pages=412–418|issn=0832-610X|doi=10.1007/s12630-009-9089-7}}</ref><ref>{{cite journal|doi=10.1016/j.jclinane.2005.04.003 [Indexed for MEDLINE]}}</ref><ref name="KrishnamoorthyDagal2014">{{cite journal|last1=Krishnamoorthy|first1=Vijay|last2=Dagal|first2=Arman|last3=Austin|first3=Naola|title=Airway management in cervical spine injury|journal=International Journal of Critical Illness and Injury Science|volume=4|issue=1|year=2014|pages=50|issn=2229-5151|doi=10.4103/2229-5151.128013}}</ref><ref name="GhafoorMartin2005">{{cite journal|last1=Ghafoor|first1=Abid U.|last2=Martin|first2=Timothy W.|last3=Gopalakrishnan|first3=Senthil|last4=Viswamitra|first4=Sanjaya|title=Caring for the patients with cervical spine injuries: what have we learned?|journal=Journal of Clinical Anesthesia|volume=17|issue=8|year=2005|pages=640–649|issn=09528180|doi=10.1016/j.jclinane.2005.04.003}}</ref><ref name="SriganeshBusse2018">{{cite journal|last1=Sriganesh|first1=Kamath|last2=Busse|first2=JasonW|last3=Shanthanna|first3=Harsha|last4=Ramesh|first4=VenkatapuraJ|title=Airway management in the presence of cervical spine instability: A cross-sectional survey of the members of the Indian Society of Neuroanaesthesiology and Critical Care|journal=Indian Journal of Anaesthesia|volume=62|issue=2|year=2018|pages=115|issn=0019-5049|doi=10.4103/ija.IJA_671_17}}</ref>
* The jaw thrust is a technique used on patients with a suspected [[spinal injury]] and is used on a [[supine position|supine]] patient.  
* The practitioner uses their thumbs to physically push the posterior (back) aspects of the mandible upwards - only possible on a patient with a GCS < 8 (although patients with a GCS higher than this should also be maintaining their own patent airway).  
* When the mandible is displaced forward, it pulls the tongue forward and prevents it from occluding (blocking) the entrance to the [[trachea]], helping to ensure a patent (secure) airway.
ILCOR no longer advocates use of the jaw thrust by lay rescuers, even for spinal injured victims, although health care professionals still maintain the technique for specific applications. Instead, lay rescuers are advised to use the same head-tilt for all victims.


===Removal of Vomit and Regurgitation===
* In the case of a patient who [[vomit]]s or has other secretions in the airway, these techniques will not be enough.
* Suitably trained clinicians may elect to use suction to clean out the airway, although this may not always be possible.
* An unconscious patient who is regurgitating stomach contents should be turned into the [[recovery position]] when there is no suction equipment available, as this allows (to a certain extent) the drainage of fluids out of the mouth instead of down the trachea.


==Adjuncts to Airway Management==
*'''Neck Maneuvers During Airway Management:'''
There are a variety of artificial airways which can be used to keep a pathway between the lungs and mouth/nose. The most commonly used in long term or critical care situations is the [[endotracheal tube]], a plastic tube which is inserted through the mouth and into the [[Vertebrate trachea|trachea]], often with a cuff which is inflated to seal off the trachea and prevent any vomit being aspirated into the lungs. In some cases, a [[laryngeal mask airway]] (LMA) is a suitable alternative to an endotracheal tube, and has the advantage of requiring a lower level of training that an ET tube.
**Immobilizing patient's [[neck]] by using sandbag-collar-tape on hardboard in a pre-hospital care setting.
**Applying pressure on cricoid with [[anterior]] half of hard [[cervical collar]] removed and another hand behind the [[posterior]] [[cervical collar]].
**Manual in-line stabilization is the technique of choice in any suspected [[cervical spine]] injury, during endotracheal intubation. In this technique, head grasped firmly at the [[mastoid process]] and the occiput.


In the case of a choking patient, [[laryngoscopy]] or even [[bronchoscopy]] may be performed in order to visualize and remove the blockage.
*Traction should be avoided as it may distract the [[cervical spine]] and cause more [[neurological]] damage, even after manual in-line stabilization.


An [[oropharyngeal airway]] or [[nasopharyngeal airway]] can be used to prevent the tongue from blocking the airway. When these airways are inserted properly, the rescuer does not need to manually open the airway with a head tilt/chin lift or jaw-thrust maneuver. Aspiration of blood, vomitus, and other fluids can still occur with these two adjuncts.
*Jaw thrust is the only basic [[airway]] opening maneuver appropriate for any [[patient]] with a suspected [[cervical spine injury]]. This method is used when head-tilt/chin-lift can be potentially dangerous to use on a patient who may have a [[cervical spine injury]]. In jaw-thrust maneuver, first care provider lifts the [[hyoid bone]] and [[tongue]] away from the [[posterior]] [[pharyngeal]] wall by pulling the [[mandible]] forward, displacing the [[tongue]] anteriorly.
*[[Suction]] and use of [[forceps]] under direct vision using a [[laryngoscope]] with the [[head]] and [[neck]] maintained in the neutral position.
*In order to minimize the risk of [[hypoxic]] damage from [[airway obstruction]] in an [[unconscious]] patient, proper positioning is done by placing patients in the [[lateral]] side with log rolling technique.
 
===Approach to airway management of a patient with Maxillo-Facial Injury===
[[Airway]] management of patients with [[maxillofacial]] trauma is challenging and vital because it's directly affecting the patient's survival. [[Endotracheal intubation]] is the [[Gold standard (test)|gold standard]] procedure to secure the [[airway]] in [[trauma]] [[patients]], however, in these [[patients]] passage of [[endotracheal tube]] may not be possible because the oral cavity, [[pharynx]], and [[larynx]] may be filled with [[blood]], secretions, [[soft tissue]], and [[bone]] fragments. Another reason for this is that the risk of [[aspiration]] and [[regurgitation]] is high in these patients.<ref name="BarakBahouth2015">{{cite journal|last1=Barak|first1=Michal|last2=Bahouth|first2=Hany|last3=Leiser|first3=Yoav|last4=Abu El-Naaj|first4=Imad|title=Airway Management of the Patient with Maxillofacial Trauma: Review of the Literature and Suggested Clinical Approach|journal=BioMed Research International|volume=2015|year=2015|pages=1–9|issn=2314-6133|doi=10.1155/2015/724032}}</ref><ref name="pmid21655009">{{cite journal |vauthors=Raval CB, Rashiduddin M |title=Airway management in patients with maxillofacial trauma - A retrospective study of 177 cases |journal=Saudi J Anaesth |volume=5 |issue=1 |pages=9–14 |date=January 2011 |pmid=21655009 |pmc=3101764 |doi=10.4103/1658-354X.76476 |url=}}</ref><ref name="pmid7588664">{{cite journal |vauthors=Brimacombe J, Tucker P, Simons S |title=The laryngeal mask airway for awake diagnostic bronchoscopy. A retrospective study of 200 consecutive patients |journal=Eur J Anaesthesiol |volume=12 |issue=4 |pages=357–61 |date=July 1995 |pmid=7588664 |doi= |url=}}</ref><ref name="HsiaoPacheco-Fowler2008">{{cite journal|last1=Hsiao|first1=James|last2=Pacheco-Fowler|first2=Victor|title=Cricothyroidotomy|journal=New England Journal of Medicine|volume=358|issue=22|year=2008|pages=e25|issn=0028-4793|doi=10.1056/NEJMvcm0706755}}</ref>
 
*In such circumstances, there are numerous [[airway]] devices are available to rescue patients with [[maxillofacial]] injuries, some of these devices include:<ref name="BarakBahouth2015">{{cite journal|last1=Barak|first1=Michal|last2=Bahouth|first2=Hany|last3=Leiser|first3=Yoav|last4=Abu El-Naaj|first4=Imad|title=Airway Management of the Patient with Maxillofacial Trauma: Review of the Literature and Suggested Clinical Approach|journal=BioMed Research International|volume=2015|year=2015|pages=1–9|issn=2314-6133|doi=10.1155/2015/724032}}</ref><ref name="MeyerPatel2014">{{cite journal|last1=Meyer|first1=TanyaK|last2=Patel|first2=SapnaA|title=Surgical Airway|journal=International Journal of Critical Illness and Injury Science|volume=4|issue=1|year=2014|pages=71|issn=2229-5151|doi=10.4103/2229-5151.128016}}</ref>
**Flexible [[fiberoptic]] [[bronchoscopy]] (FOB), enable an indirect view of [[vocal cords]].
**[[Laryngeal mask airway]] (LMA) may be inserted blindly since it does not require a view of the [[vocal cords]]. Another option for securing the [[airway]] in these patients is to pass the endotracheal tube after placing an LMA for them.
*Final option for establishing the airway in [[patients]] with [[maxillofacial]] injury is [[surgery]] by [[cricothyroidotomy]].
**[[Cricothyroidotomy]] also known as [[cricothyrotomy]] is a procedure done by trained [[health care providers]], they make a small [[incision]] through the skin and [[cricoid]] membrane which lies between the [[thyroid]] and [[cricoid]] [[cartilage]]<nowiki/>s, followed by inserting a [[tracheostomy tube]] to open alternative way of [[ventilation]] and [[oxygenation]] in the [[emergency]] situation which uses of [[endotracheal intubation]] is almost impossible or difficult and time-consuming.
**'''Indication for cricothyroidotomy include:'''
***Inability to secure [[airway]] through an [[endotracheal tube]]
***Major [[trauma]] to [[facial]] [[muscles]], [[pharynx]], [[larynx]].
***[[Congenital deformities]] and [[upper airway]] [[stenosis]].
 
*'''Contraindications for cricothyroidotomy:'''
**[[Age]], in [[pediatrics]] younger than 12 years old needle [[cricothyrotomy]] is indicated because of less potential damage to the [[larynx]] and surrounding structures.
**Massive [[trauma]] to the [[larynx]] or [[cricoid cartilage]]
**Inability to identify surface landmarks due to [[obesity]], [[cervical]] trauma.
**When [[Orotracheal intubation|orotracheal]] and [[Nasotracheal intubation|nasotracheal]] [[intubation]] are viable options
**[[Airway obstruction]] distal to [[subglottic airway]], e.g. [[tracheal stenosis]]
**[[Laryngeal cancer]]: Other than for an extreme airway [[emergency]], [[cricothyroidotomy]] must be avoided to not to seed the [[soft tissue]] of the [[neck]] with [[cancer]] cells
**[[Coagulopathy]] (other than [[emergency]] situation)
 
*'''Complications of cricothyroidotomy:'''
**[[Esophageal]] perforation if the blade penetrates too deeply.
**[[Subcutaneous emphysema]]
**Rupture of vital [[vessels]] such as a [[carotid artery]], excessive [[bleeding]], and [[hemorrhage]].
 
*'''Indications of definitive airway management in patients with maxillofacial injury:'''
**Absent spontaneous [[breathing]]
**[[Comatose]] [[patients]]([[Glasgow coma score]] < 9)
**[[Airway]] injury or [[obstruction]]
**Persistent [[oxygen saturation]] below 90%
**High risk for [[aspiration]]
**[[Systemic shock]]([[Systolic Blood Pressure Intervention|Systolic Blood Pressure]]<80mmHg)
**"Cannot intubate, cannot ventilate" situations
 
==Complications of airway management==
 
Airway management complications are common, these complications usually occur in [[intensive care units]] and [[emergency department]]<nowiki/>s, summary of airway management related complactions include:<ref name="CookMacDougall-Davis2012">{{cite journal|last1=Cook|first1=T.M.|last2=MacDougall-Davis|first2=S.R.|title=Complications and failure of airway management|journal=British Journal of Anaesthesia|volume=109|year=2012|pages=i68–i85|issn=00070912|doi=10.1093/bja/aes393}}</ref>
 
*[[Patient]] harm/death associated with suboptimal care
*[[Hypoxia]] is the most common cause of [[airway]]-related deaths
*[[Obesity]]
*[[Pulmonary]] [[aspiration]] remains the leading cause of airway-related [[anesthetic]] deaths
*Failure in airway management techniques
 
 
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==Related Chapters==
==Related Chapters==
*[[intubation|Intubation]]
*[[intubation|Intubation]]
*[[endotracheal tube|Endotracheal Tube]]
*[[endotracheal tube|Endotracheal Tube]]
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==References==
==References==
<references />
{{reflist|2}}
{{cite book
  | last = 
  | coauthors = Daniel Limmer, Keith J. Karren, Brent Q. Hafen, John Mackay, Michelle Mackay
  | title = Emergency Medical Responder (Second Canadian Version)
  | publisher = Brady
  | date = 2006
  | pages = 92-97
  | isbn = 0-13-127824-X }}
 
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:First aid]]
[[Category:First aid]]
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[[Category:Intensive care medicine]]
[[Category:Intensive care medicine]]


[[de:Airway-Management]]
[[ja:気道確保]]
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Airway management is the process of ensuring that there is an open pathway between a patient’s lungs and the outside world, and the lungs are safe from aspiration. Airway loss is a major cause of preventable prehospital death in trauma patients. Airway management complications are common, especially in trauma patients because of associated pathology, lack of complete evaluation before intubation, unanticipated difficulty during ventilation and intubation. Additionally, trauma patients are at increased risk of airway obstruction, aspiration, hypoxia and hypotension, and other unstable vital The providers must have skillset related to working with a variety of tools and techniques used in airway management and knowledge of the important anatomical, physiological, and pathological features related to the airway. They also should know the differences between the adult versus pediatric and neonatal airways as these anatomical and physiological differences are critical, impactful on patients lives and knowing these leads to effective control and management of the airway. Some of the indications for managing the airway in patients include respiratory failure, altered sensorium(Glasgow Coma Scale less than or equal to 8), rapid deterioration of mental status, airway injury or compromise, injuries causing a high risk for aspiration-which includes all penetrating injuries to the abdomen or chest wall. Inadequate airway management may lead to cardiovascular arrest and compromise life-saving interventions in a trauma patient. Several airway control devices and techniques are available to assist healthcare providers in order to maintain the airway by ventilation and oxygenation. These include bag valve mask (BVM) ventilation, direct laryngoscopy with endotracheal intubation (ETI) and adjunct supraglottic airway devices such as the laryngeal mask airway.

Functional anatomy of the upper airway

For a successful approach to airway management, health care providers must have knowledge of important anatomical, physiological, and pathological features related to the airway as well as knowledge of the various equipment and methods that can be utilized for this purpose. Also, the difference between airway management in adults, pediatrics, and neonates is very critical.[1]


upper airway systemstaff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436.


Recommendations for evaluation of airway

The basic approach in airway management in the emergency setting includes:[2]

Following are steps that must be considered prior to conducting airway management, these include:

  • History: An airway history should be conducted whenever it is possible before airway management in all patients to detect medical, surgical, and anesthetic factors that may indicate the presence of a difficult airway. A detailed review of previous anesthetic records, if available, may provide useful information about airway management.
  • Physical Examination: An airway physical examination should be conducted before the initiation of airway management. The goal of physical examination is to detect physical characteristics that may indicate the presence of a difficult airway because an unsuccessful airway management is associated with increase in mortality and morbidity.
  • Additional Evaluation: Additional evaluation may be indicated in some patients to characterize the likelihood or nature of the anticipated difficult airway. Certain diagnostic tests (e.g., radiography, computed tomography scans, fluoroscopy) can identify a variety of acquired or congenital features in patients with difficult airways

Techniques for airway management

The decision about whether an airway intervention is required or not is crucial for patient's survival and depends on first responders skills and quick assessment and decision. These crucial steps requires techniques which are used universally in order to manage patient's airway. Following are initial evaluation methods which had been developed to assist patient's ventilation and keep the airway patent, these techniques include:[3][4][5][6][7]

  • Spontaneous breathing: When a provider is confronted with an awake patient having a patent airway. Spontaneous ventilation can be assisted through the placement of a nasal or oral airway. Oxygenation can be improved by giving oxygen via nasal cannula, simple face mask, or nonrebreather face mask. Unfortunately, the maximally achieved FiO2 is often overestimated by care providers and hypoventilation resulting in hypercapnia cannot be normalized with increase in oxygen supply.
  • Mouth-to-Mouth ventilation: Mouth-to-mouth or mouth-to-nose ventilation is a useful management technique, however, because of the risk of infection transmission it is recommended by American heart association that health care providers do "Hands-only" CPR. Proper face masks should be utilized if they are available.
  • Bag-mask ventilation: It is a standard initial approach to airway management in the prehospital and hospital settings.
  • Oropharyngeal and nasopharyngeal airways:
  • Supraglottic airway devices: Supraglottic airway (SGA) device placement is very useful to keep the airways open, it has advantages in comparison with endotracheal tube intubation, or other methods, these advantages include:[8]


  • Rapid sequence intubation:
Photograph of an anesthesiologist using the Glidescope video laryngoscope to intubate the trachea of a morbidly obese elderly person with challenging airway anatomy(DiverDave (talk)) created this work entirely by myself. (Original uploaded on en.wikipedia)


Management of the Airway in Patients with Trauma

Difficult airway

Suspected Spinal Cord Injury


  • Neck Maneuvers During Airway Management:
    • Immobilizing patient's neck by using sandbag-collar-tape on hardboard in a pre-hospital care setting.
    • Applying pressure on cricoid with anterior half of hard cervical collar removed and another hand behind the posterior cervical collar.
    • Manual in-line stabilization is the technique of choice in any suspected cervical spine injury, during endotracheal intubation. In this technique, head grasped firmly at the mastoid process and the occiput.
  • Traction should be avoided as it may distract the cervical spine and cause more neurological damage, even after manual in-line stabilization.

Approach to airway management of a patient with Maxillo-Facial Injury

Airway management of patients with maxillofacial trauma is challenging and vital because it's directly affecting the patient's survival. Endotracheal intubation is the gold standard procedure to secure the airway in trauma patients, however, in these patients passage of endotracheal tube may not be possible because the oral cavity, pharynx, and larynx may be filled with blood, secretions, soft tissue, and bone fragments. Another reason for this is that the risk of aspiration and regurgitation is high in these patients.[14][15][16][17]

Complications of airway management

Airway management complications are common, these complications usually occur in intensive care units and emergency departments, summary of airway management related complactions include:[19]


{{#ev:youtube|ycQs27YVE60}}

Related Chapters

References

  1. Morris IR (November 1988). "Functional anatomy of the upper airway". Emerg. Med. Clin. North Am. 6 (4): 639–69. PMID 3056703.
  2. Rosenberg, M. B; Phero, J. C; Becker, D. E (2014). "Essentials of Airway Management, Oxygenation, and Ventilation: Part 2: Advanced Airway Devices: Supraglottic Airways". Anesthesia Progress. 61 (3): 113–118. doi:10.2344/0003-3006-61.3.113. ISSN 0003-3006.
  3. Roychoudhury, Ajoy; Jose, Anson; Nagori, ShakilAhmed; Agarwal, Bhaskar; Bhutia, Ongkila (2016). "Management of maxillofacial trauma in emergency: An update of challenges and controversies". Journal of Emergencies, Trauma, and Shock. 9 (2): 73. doi:10.4103/0974-2700.179456. ISSN 0974-2700.
  4. Agrò FE, Cataldo R, Mattei A (March 2009). "New devices and techniques for airway management". Minerva Anestesiol. 75 (3): 141–9. PMID 18946431.
  5. Gleason JM, Christian BR, Barton ED (March 2018). "Nasal Cannula Apneic Oxygenation Prevents Desaturation During Endotracheal Intubation: An Integrative Literature Review". West J Emerg Med. 19 (2): 403–411. doi:10.5811/westjem.2017.12.34699. PMC 5851518. PMID 29560073.
  6. Law, J. Adam; Broemling, Natasha; Cooper, Richard M.; Drolet, Pierre; Duggan, Laura V.; Griesdale, Donald E.; Hung, Orlando R.; Jones, Philip M.; Kovacs, George; Massey, Simon; Morris, Ian R.; Mullen, Timothy; Murphy, Michael F.; Preston, Roanne; Naik, Viren N.; Scott, Jeanette; Stacey, Shean; Turkstra, Timothy P.; Wong, David T. (2013). "The difficult airway with recommendations for management – Part 1 – Difficult tracheal intubation encountered in an unconscious/induced patient". Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 60 (11): 1089–1118. doi:10.1007/s12630-013-0019-3. ISSN 0832-610X.
  7. Okubo, Masashi; Gibo, Koichiro; Hagiwara, Yusuke; Nakayama, Yukiko; Hasegawa, Kohei (2017). "The effectiveness of rapid sequence intubation (RSI) versus non-RSI in emergency department: an analysis of multicenter prospective observational study". International Journal of Emergency Medicine. 10 (1). doi:10.1186/s12245-017-0129-8. ISSN 1865-1372.
  8. Park SK, Ko G, Choi GJ, Ahn EJ, Kang H (August 2016). "Comparison between supraglottic airway devices and endotracheal tubes in patients undergoing laparoscopic surgery: A systematic review and meta-analysis". Medicine (Baltimore). 95 (33): e4598. doi:10.1097/MD.0000000000004598. PMID 27537593.
  9. Thiboutot, François; Nicole, Pierre C.; Trépanier, Claude A.; Turgeon, Alexis F.; Lessard, Martin R. (2009). "Effect of manual in-line stabilization of the cervical spine in adults on the rate of difficult orotracheal intubation by direct laryngoscopy: a randomized controlled trial". Canadian Journal of Anesthesia/Journal Canadien d'anesthésie. 56 (6): 412–418. doi:10.1007/s12630-009-9089-7. ISSN 0832-610X.
  10. . doi:10.1016/j.jclinane.2005.04.003 [Indexed for MEDLINE] Check |doi= value (help). Missing or empty |title= (help)
  11. Krishnamoorthy, Vijay; Dagal, Arman; Austin, Naola (2014). "Airway management in cervical spine injury". International Journal of Critical Illness and Injury Science. 4 (1): 50. doi:10.4103/2229-5151.128013. ISSN 2229-5151.
  12. Ghafoor, Abid U.; Martin, Timothy W.; Gopalakrishnan, Senthil; Viswamitra, Sanjaya (2005). "Caring for the patients with cervical spine injuries: what have we learned?". Journal of Clinical Anesthesia. 17 (8): 640–649. doi:10.1016/j.jclinane.2005.04.003. ISSN 0952-8180.
  13. Sriganesh, Kamath; Busse, JasonW; Shanthanna, Harsha; Ramesh, VenkatapuraJ (2018). "Airway management in the presence of cervical spine instability: A cross-sectional survey of the members of the Indian Society of Neuroanaesthesiology and Critical Care". Indian Journal of Anaesthesia. 62 (2): 115. doi:10.4103/ija.IJA_671_17. ISSN 0019-5049.
  14. 14.0 14.1 Barak, Michal; Bahouth, Hany; Leiser, Yoav; Abu El-Naaj, Imad (2015). "Airway Management of the Patient with Maxillofacial Trauma: Review of the Literature and Suggested Clinical Approach". BioMed Research International. 2015: 1–9. doi:10.1155/2015/724032. ISSN 2314-6133.
  15. Raval CB, Rashiduddin M (January 2011). "Airway management in patients with maxillofacial trauma - A retrospective study of 177 cases". Saudi J Anaesth. 5 (1): 9–14. doi:10.4103/1658-354X.76476. PMC 3101764. PMID 21655009.
  16. Brimacombe J, Tucker P, Simons S (July 1995). "The laryngeal mask airway for awake diagnostic bronchoscopy. A retrospective study of 200 consecutive patients". Eur J Anaesthesiol. 12 (4): 357–61. PMID 7588664.
  17. Hsiao, James; Pacheco-Fowler, Victor (2008). "Cricothyroidotomy". New England Journal of Medicine. 358 (22): e25. doi:10.1056/NEJMvcm0706755. ISSN 0028-4793.
  18. Meyer, TanyaK; Patel, SapnaA (2014). "Surgical Airway". International Journal of Critical Illness and Injury Science. 4 (1): 71. doi:10.4103/2229-5151.128016. ISSN 2229-5151.
  19. Cook, T.M.; MacDougall-Davis, S.R. (2012). "Complications and failure of airway management". British Journal of Anaesthesia. 109: i68–i85. doi:10.1093/bja/aes393. ISSN 0007-0912.


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