Zollinger-Ellison syndrome historical perspective: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(2 intermediate revisions by one other user not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__


{{CMG}} {{AE}} {{ARK}}
{{CMG}} {{AE}}{{S.M}}
{{Zollinger-Ellison syndrome}}
{{Zollinger-Ellison syndrome}}


==Overview==
==Overview==
In 1955, Zollinger and Ellison published their seminal paper on gastrinomas wherein the Zollinger-Ellison syndrome was first discussed.
In 1955, Zollinger and Ellison published their seminal paper on gastrinomas wherein the Zollinger-Ellison syndrome was discussed for the first time.


==Historical Perspective==
==Historical Perspective==
* In 1955, Zollinger and Ellison announced their concept about ulcerogenic islet cell tumor which caused marked ulcer diathesis due to gastric hyperacidity.<ref name="pmid1746876">{{cite journal| author=Zollinger RM| title=[The history of the Zollinger-Ellison syndrome]. | journal=Ann Gastroenterol Hepatol (Paris) | year= 1991 | volume= 27 | issue= 5 | pages= 223-6 | pmid=1746876 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1746876  }} </ref>
* In 1955, Zollinger and Ellison announced their concept about [[Ulcer|ulcerogenic]] [[islet cell]] [[tumor]] which caused marked [[ulcer]] diathesis due to [[Stomach|gastric]] hyperacidity.<ref name="pmid1746876">{{cite journal| author=Zollinger RM| title=[The history of the Zollinger-Ellison syndrome]. | journal=Ann Gastroenterol Hepatol (Paris) | year= 1991 | volume= 27 | issue= 5 | pages= 223-6 | pmid=1746876 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1746876  }} </ref>
* Dr. Robert M. Zollinger and Dr. Edwin H. Ellison announced their theory at annual meeting of the American Surgical Association in Philadelphia in April 1956.<ref name="pmid13259432">{{cite journal| author=ZOLLINGER RM, ELLISON EH| title=Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. | journal=Ann Surg | year= 1955 | volume= 142 | issue= 4 | pages= 709-23; discussion, 724-8 | pmid=13259432 | doi= | pmc=1465210 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13259432  }} </ref>
* Dr. Robert M. Zollinger and Dr. Edwin H. Ellison announced their theory at the annual meeting of American Surgical Association in Philadelphia in April 1956.<ref name="pmid13259432">{{cite journal| author=ZOLLINGER RM, ELLISON EH| title=Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. | journal=Ann Surg | year= 1955 | volume= 142 | issue= 4 | pages= 709-23; discussion, 724-8 | pmid=13259432 | doi= | pmc=1465210 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13259432  }} </ref>
* This concept raised from clinical case of two women who presented with perforated jejunal ulcers accompanied with severe ulcer diathesis.
* This concept raised from [[clinical]] case of two women who presented with perforated [[Jejunum|jejunal]] [[Ulcer|ulcers]] accompanied with severe [[ulcer]] diathesis.
* One of the patients was a 36 year-old woman with past history of 8 years abdominal pain and diarrhea. A laparotomy revealed perforated jejunal ulcers with severe recurrent hemorrhage. Although she underwent two subtotal gastric resections, transabdominal vagotomy, and transthoracic vagotomy, her symptoms were constantly persistant. Finally she underwent total gastrectomy; however, she died due to anastomic leakage from the surgery. Her autopsy was in favor of non-beta pancreatic islet cell tumors.<ref name="KaplanTanaka1994">{{cite journal|last1=Kaplan|first1=Edwin L.|last2=Tanaka|first2=Reiko|last3=Ito|first3=Koichi|last4=Younes|first4=Nidal|last5=Friesen|first5=Stanley R.|title=The discovery of the Zollinger-Ellison syndrome|journal=Journal of Hepato-Biliary-Pancreatic Surgery|volume=1|issue=5|year=1994|pages=509–516|issn=0944-1166|doi=10.1007/BF01211912}}</ref>
* One of the [[patients]] was a 36 year-old woman with past history of 8 years [[abdominal pain]] and [[diarrhea]]. A [[laparotomy]] revealed [[Perforated ulcer|perforated]] [[Jejunum|jejunal]] [[Ulcer|ulcers]] with severe recurrent [[Bleeding|hemorrhage]]. Although she underwent two subtotal [[Stomach|gastric]] [[Resection|resections]], transabdominal [[vagotomy]], and transthoracic [[vagotomy]], her [[Symptom|symptoms]] were constantly persistent. Finally she underwent total [[gastrectomy]]; however, she died due to [[Anastomosis|anastomic]] leakage from the [[surgery]]. Her [[autopsy]] was in favor of non-beta [[Pancreas|pancreatic]] [[islet cell]] [[tumor]].<ref name="KaplanTanaka1994">{{cite journal|last1=Kaplan|first1=Edwin L.|last2=Tanaka|first2=Reiko|last3=Ito|first3=Koichi|last4=Younes|first4=Nidal|last5=Friesen|first5=Stanley R.|title=The discovery of the Zollinger-Ellison syndrome|journal=Journal of Hepato-Biliary-Pancreatic Surgery|volume=1|issue=5|year=1994|pages=509–516|issn=0944-1166|doi=10.1007/BF01211912}}</ref>
* The other patient was a 19 year-old women with 2 years of upper abdominal pain. She underwent a surgery in July 1953 and diagnosed with two perforated jejunal ulcers. A truncal vagotomy and a radical subtotal gastrectomy were performed in January 1954. This operation was called as a dream operation for ulcers by Zollinger. Due to unsuccessful results of the operation, she experienced radiation therapy to her stomach. Eventually, total gastrectomy was performed. The results described a non-beta islet cell carcinoma with lymph node metastasis. Hopefully she survived and gave birth to two children.
* The other [[patient]] was a 19 year-old woman with 2 years of [[upper abdominal pain]]. She underwent a [[surgery]] in July 1953 and was [[Diagnosis|diagnosed]] with two [[Perforated ulcer|perforated]] [[Jejunum|jejunal]] [[Ulcer|ulcers]]. A truncal [[vagotomy]] and a radical subtotal [[gastrectomy]] were performed in January 1954. This operation was called a dream operation for [[Ulcer|ulcers]] by Zollinger. Due to unsuccessful results of the operation, she had to go through [[radiation therapy]] to her [[stomach]]. Eventually, total [[gastrectomy]] was performed. The results described a non-beta [[islet cell]] [[carcinoma]] with [[lymph node]] [[metastasis]].
* In 1956, Ben Eiseman of Denver, Colorado, presented the same experience with one of his patients and called the condition as a Zollinger-Ellison syndrome.<ref name="pmid2757418">{{cite journal| author=Chey WY, Chang TM, Lee KY, Sun G, Kim CK, You CH et al.| title=Ulcerogenic tumor syndrome of the pancreas associated with a nongastrin acid secretagogue. | journal=Ann Surg | year= 1989 | volume= 210 | issue= 2 | pages= 139-49 | pmid=2757418 | doi= | pmc=1357819 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2757418  }}</ref>
* In 1956, Ben Eiseman of Denver, Colorado, presented the same experience with one of his [[Patient|patients]] and called the condition "Zollinger-Ellison syndrome".<ref name="pmid2757418">{{cite journal| author=Chey WY, Chang TM, Lee KY, Sun G, Kim CK, You CH et al.| title=Ulcerogenic tumor syndrome of the pancreas associated with a nongastrin acid secretagogue. | journal=Ann Surg | year= 1989 | volume= 210 | issue= 2 | pages= 139-49 | pmid=2757418 | doi= | pmc=1357819 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2757418  }}</ref>
* Discovery of insulinoma in 1927 and malignant carcinoid syndrome in 1953, have exceeded the presentation and discovery of Zollinger-Ellison syndrome.<ref name="WilderAllan1927">{{cite journal|last1=Wilder|first1=Russell M.|last2=Allan|first2=Frank N.|last3=Power|first3=M. H.|last4=Robertson|first4=H. E.|title=CARCINOMA OF THE ISLANDS OF THE PANCREAS|journal=Journal of the American Medical Association|volume=89|issue=5|year=1927|pages=348|issn=0002-9955|doi=10.1001/jama.1927.02690050014007}}</ref><ref name="pmid24319020">{{cite journal| author=Epelboym I, Mazeh H| title=Zollinger-Ellison syndrome: classical considerations and current controversies. | journal=Oncologist | year= 2014 | volume= 19 | issue= 1 | pages= 44-50 | pmid=24319020 | doi=10.1634/theoncologist.2013-0369 | pmc=3903066 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24319020  }} </ref>
* Discovery of [[insulinoma]] in 1927 and [[malignant carcinoid syndrome]] in 1953, have exceeded the presentation and discovery of Zollinger-Ellison syndrome.<ref name="WilderAllan1927">{{cite journal|last1=Wilder|first1=Russell M.|last2=Allan|first2=Frank N.|last3=Power|first3=M. H.|last4=Robertson|first4=H. E.|title=CARCINOMA OF THE ISLANDS OF THE PANCREAS|journal=Journal of the American Medical Association|volume=89|issue=5|year=1927|pages=348|issn=0002-9955|doi=10.1001/jama.1927.02690050014007}}</ref><ref name="pmid24319020">{{cite journal| author=Epelboym I, Mazeh H| title=Zollinger-Ellison syndrome: classical considerations and current controversies. | journal=Oncologist | year= 2014 | volume= 19 | issue= 1 | pages= 44-50 | pmid=24319020 | doi=10.1634/theoncologist.2013-0369 | pmc=3903066 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24319020  }} </ref>
*In 1960s, gastrin was described as a main pathogenesis of gastric hyperacidity by Dr. Lester.<ref name="pmid17053435">{{cite journal| author=Hou W, Schubert ML| title=Gastric secretion. | journal=Curr Opin Gastroenterol | year= 2006 | volume= 22 | issue= 6 | pages= 593-8 | pmid=17053435 | doi=10.1097/01.mog.0000245538.43142.87 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17053435  }} </ref>
*In the 1960s, [[gastrin]] was described to be involved in the [[pathogenesis]] of gastric hyperacidity by Dr. Lester.<ref name="pmid17053435">{{cite journal| author=Hou W, Schubert ML| title=Gastric secretion. | journal=Curr Opin Gastroenterol | year= 2006 | volume= 22 | issue= 6 | pages= 593-8 | pmid=17053435 | doi=10.1097/01.mog.0000245538.43142.87 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17053435  }} </ref>
* Roderic Gregory and Hilda Tracy of Liverpool proved that gastrin is the cause of Zollinger-Ellison syndrome. <ref name="pmid3851712">{{cite journal| author=Leske JS| title=Hyperglycemic hyperosmolar nonketotic coma: a nursing care plan. | journal=Crit Care Nurse | year= 1985 | volume= 5 | issue= 5 | pages= 49-56 | pmid=3851712 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3851712  }}</ref>
* Roderic Gregory and Hilda Tracy of Liverpool proved that [[gastrin]] is the cause of Zollinger-Ellison syndrome. <ref name="pmid3851712">{{cite journal| author=Leske JS| title=Hyperglycemic hyperosmolar nonketotic coma: a nursing care plan. | journal=Crit Care Nurse | year= 1985 | volume= 5 | issue= 5 | pages= 49-56 | pmid=3851712 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3851712  }}</ref>
* Radioimmunoassay was developed for assessment of gastrin level in 1967 and 1968.<ref name="StrempleAbramoff1967">{{cite journal|last1=Stremple|first1=JohnF.|last2=Abramoff|first2=Peter|last3=Van Oss|first3=CarelJ.|last4=Wilson|first4=StuartD.|last5=Ellison|first5=EdwinH.|title=ANTIBODIES TO SYNTHETIC HUMAN GASTRIN I|journal=The Lancet|volume=290|issue=7527|year=1967|pages=1180–1182|issn=01406736|doi=10.1016/S0140-6736(67)91895-8}}</ref><ref name="McGuiganTrudeau1968">{{cite journal|last1=McGuigan|first1=James E.|last2=Trudeau|first2=Walter L.|title=Immunochemical Measurement of Elevated Levels of Gastrin in the Serum of Patients with Pancreatic Tumors of the Zollinger-Ellison Variety|journal=New England Journal of Medicine|volume=278|issue=24|year=1968|pages=1308–1313|issn=0028-4793|doi=10.1056/NEJM196806132782402}}</ref>
*[[Radioimmunoassay]] was developed for assessment of [[gastrin]] level in 1967 and 1968.<ref name="StrempleAbramoff1967">{{cite journal|last1=Stremple|first1=JohnF.|last2=Abramoff|first2=Peter|last3=Van Oss|first3=CarelJ.|last4=Wilson|first4=StuartD.|last5=Ellison|first5=EdwinH.|title=ANTIBODIES TO SYNTHETIC HUMAN GASTRIN I|journal=The Lancet|volume=290|issue=7527|year=1967|pages=1180–1182|issn=01406736|doi=10.1016/S0140-6736(67)91895-8}}</ref><ref name="McGuiganTrudeau1968">{{cite journal|last1=McGuigan|first1=James E.|last2=Trudeau|first2=Walter L.|title=Immunochemical Measurement of Elevated Levels of Gastrin in the Serum of Patients with Pancreatic Tumors of the Zollinger-Ellison Variety|journal=New England Journal of Medicine|volume=278|issue=24|year=1968|pages=1308–1313|issn=0028-4793|doi=10.1056/NEJM196806132782402}}</ref>
*[[H2 blocker|Histamine-2 blocking drugs (H2)]] were introduced as the first effective medical therapy for Zollinger-Ellison syndrome in 1975.<ref name="pmid1124750">{{cite journal| author=Mainardi M, Maxwell V, Sturdevant RA, Isenberg JI| title=Inhibition of gastric acid secretion by metiamide in Zollinger-Ellison syndrome. | journal=Am J Dig Dis | year= 1975 | volume= 20 | issue= 3 | pages= 280-1 | pmid=1124750 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1124750  }}</ref>


==References==
==References==

Latest revision as of 21:17, 11 September 2019


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Zollinger-Ellison syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Zollinger-Ellison syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Zollinger-Ellison syndrome historical perspective On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Zollinger-Ellison syndrome historical perspective

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Zollinger-Ellison syndrome historical perspective

CDC on Zollinger-Ellison syndrome historical perspective

Zollinger-Ellison syndrome historical perspective in the news

Blogs on Zollinger-Ellison syndrome historical perspective

Directions to Hospitals Treating Zollinger-Ellison syndrome

Risk calculators and risk factors for Zollinger-Ellison syndrome historical perspective

Overview

In 1955, Zollinger and Ellison published their seminal paper on gastrinomas wherein the Zollinger-Ellison syndrome was discussed for the first time.

Historical Perspective

References

  1. Zollinger RM (1991). "[The history of the Zollinger-Ellison syndrome]". Ann Gastroenterol Hepatol (Paris). 27 (5): 223–6. PMID 1746876.
  2. ZOLLINGER RM, ELLISON EH (1955). "Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas". Ann Surg. 142 (4): 709–23, discussion, 724–8. PMC 1465210. PMID 13259432.
  3. Kaplan, Edwin L.; Tanaka, Reiko; Ito, Koichi; Younes, Nidal; Friesen, Stanley R. (1994). "The discovery of the Zollinger-Ellison syndrome". Journal of Hepato-Biliary-Pancreatic Surgery. 1 (5): 509–516. doi:10.1007/BF01211912. ISSN 0944-1166.
  4. Chey WY, Chang TM, Lee KY, Sun G, Kim CK, You CH; et al. (1989). "Ulcerogenic tumor syndrome of the pancreas associated with a nongastrin acid secretagogue". Ann Surg. 210 (2): 139–49. PMC 1357819. PMID 2757418.
  5. Wilder, Russell M.; Allan, Frank N.; Power, M. H.; Robertson, H. E. (1927). "CARCINOMA OF THE ISLANDS OF THE PANCREAS". Journal of the American Medical Association. 89 (5): 348. doi:10.1001/jama.1927.02690050014007. ISSN 0002-9955.
  6. Epelboym I, Mazeh H (2014). "Zollinger-Ellison syndrome: classical considerations and current controversies". Oncologist. 19 (1): 44–50. doi:10.1634/theoncologist.2013-0369. PMC 3903066. PMID 24319020.
  7. Hou W, Schubert ML (2006). "Gastric secretion". Curr Opin Gastroenterol. 22 (6): 593–8. doi:10.1097/01.mog.0000245538.43142.87. PMID 17053435.
  8. Leske JS (1985). "Hyperglycemic hyperosmolar nonketotic coma: a nursing care plan". Crit Care Nurse. 5 (5): 49–56. PMID 3851712.
  9. Stremple, JohnF.; Abramoff, Peter; Van Oss, CarelJ.; Wilson, StuartD.; Ellison, EdwinH. (1967). "ANTIBODIES TO SYNTHETIC HUMAN GASTRIN I". The Lancet. 290 (7527): 1180–1182. doi:10.1016/S0140-6736(67)91895-8. ISSN 0140-6736.
  10. McGuigan, James E.; Trudeau, Walter L. (1968). "Immunochemical Measurement of Elevated Levels of Gastrin in the Serum of Patients with Pancreatic Tumors of the Zollinger-Ellison Variety". New England Journal of Medicine. 278 (24): 1308–1313. doi:10.1056/NEJM196806132782402. ISSN 0028-4793.
  11. Mainardi M, Maxwell V, Sturdevant RA, Isenberg JI (1975). "Inhibition of gastric acid secretion by metiamide in Zollinger-Ellison syndrome". Am J Dig Dis. 20 (3): 280–1. PMID 1124750.

Template:WH Template:WS