Barrett's esophagus risk factors: Difference between revisions

Jump to navigation Jump to search
 
(25 intermediate revisions by 2 users not shown)
Line 3: Line 3:




{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{AMK}}
==Overview==
==Overview==


The most potent risk factor in the development of [[Barret's Oesophagus]] is Chronic [[GERD]]. Other risk factors include Age (>older than 50 years), Sex (male), Race (caucasian), hiatal hernia, elevated body mass index and intra-abdominal distribution of body fat.
The most potent [[risk factor]] in the [[development]] of Barrett's Oesophagus is [[chronic]] [[GERD]]. Other [[risk factors]] include [[age]] (>older than 50 years), sex ([[male]]), [[race]] (caucasian), [[hiatal hernia]], elevated [[body mass index]] and intra-abdominal distribution of [[body]] [[fat]].


==Risk factors==
==Risk factors==
* Age: older than 50 years
The followings are the [[risk factors]] for the Barrett's esophagus;
* Sex: male
* [[Age]]: Older than 50 years
* Race: caucasian
* Sex: Male>female<ref name="pmid16221805">{{cite journal| author=Cook MB, Wild CP, Forman D| title=A systematic review and meta-analysis of the sex ratio for Barrett's esophagus, erosive reflux disease, and nonerosive reflux disease. | journal=Am J Epidemiol | year= 2005 | volume= 162 | issue= 11 | pages= 1050-61 | pmid=16221805 | doi=10.1093/aje/kwi325 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16221805  }} </ref><ref name="pmid26414697">{{cite journal| author=Ek WE, Lagergren K, Cook M, Wu AH, Abnet CC, Levine D et al.| title=Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma. | journal=Int J Cancer | year= 2016 | volume= 138 | issue= 5 | pages= 1146-52 | pmid=26414697 | doi=10.1002/ijc.29863 | pmc=4715576 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26414697  }} </ref>
* Other: chronic GERD, hiatal hernia, elevated body mass index, and intra-abdominal distribution of body fat.<ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 | |url=}}</ref>
* [[Race]]: Caucasian
* [[Other]]:<ref name="pmid10929625">{{cite journal| author=von Schrenck T| title=[Diagnosis of gastroesophageal reflux and Barrett esophagus]. | journal=Zentralbl Chir | year= 2000 | volume= 125 | issue= 5 | pages= 414-23 | pmid=10929625 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10929625  }} </ref><ref name="pmid28336546">{{cite journal| author=Minacapelli CD, Bajpai M, Geng X, Cheng CL, Chouthai AA, Souza R et al.| title=Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux. | journal=Am J Physiol Gastrointest Liver Physiol | year= 2017 | volume= 312 | issue= 6 | pages= G615-G622 | pmid=28336546 | doi=10.1152/ajpgi.00268.2016 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28336546  }} </ref><ref name="pmid17461453">{{cite journal| author=Anderson LA, Watson RG, Murphy SJ, Johnston BT, Comber H, Mc Guigan J et al.| title=Risk factors for Barrett's oesophagus and oesophageal adenocarcinoma: results from the FINBAR study. | journal=World J Gastroenterol | year= 2007 | volume= 13 | issue= 10 | pages= 1585-94 | pmid=17461453 | doi= | pmc=4146903 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17461453  }} </ref><ref name="pmid19336423">{{cite journal| author=Jacobson BC, Chan AT, Giovannucci EL, Fuchs CS| title=Body mass index and Barrett's oesophagus in women. | journal=Gut | year= 2009 | volume= 58 | issue= 11 | pages= 1460-6 | pmid=19336423 | doi=10.1136/gut.2008.174508 | pmc=2763036 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19336423  }} </ref><ref name="pmid17681161">{{cite journal| author=Edelstein ZR, Farrow DC, Bronner MP, Rosen SN, Vaughan TL| title=Central adiposity and risk of Barrett's esophagus. | journal=Gastroenterology | year= 2007 | volume= 133 | issue= 2 | pages= 403-11 | pmid=17681161 | doi=10.1053/j.gastro.2007.05.026 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17681161  }} </ref><ref name="pmid19161814">{{cite journal| author=Kamat P, Wen S, Morris J, Anandasabapathy S| title=Exploring the association between elevated body mass index and Barrett's esophagus: a systematic review and meta-analysis. | journal=Ann Thorac Surg | year= 2009 | volume= 87 | issue= 2 | pages= 655-62 | pmid=19161814 | doi=10.1016/j.athoracsur.2008.08.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19161814  }} </ref><ref name="pmid21376940">{{cite journal |author=Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ |title=American Gastroenterological Association medical position statement on the management of Barrett's esophagus |journal=Gastroenterology |volume=140 |issue=3 |pages=1084–91 |year=2011 |month=March |pmid=21376940 | |url=}}</ref>
** Chronic [[GERD]]
** Hiatal hernia
** Elevated [[body mass index]]
** Intra-abdominal distribution of [[body]] [[fat]]
 
==Protective factors==
*[[Barrett's esophagus]] is less common in [[patients]] having [[Helicobacter pylori]] [[infection]].<ref name="pmid27681974">{{cite journal| author=Whiteman DC, Kendall BJ| title=Barrett's oesophagus: epidemiology, diagnosis and clinical management. | journal=Med J Aust | year= 2016 | volume= 205 | issue= 7 | pages= 317-24 | pmid=27681974 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27681974  }} </ref><ref name="pmid17997357">{{cite journal| author=Rokkas T, Pistiolas D, Sechopoulos P, Robotis I, Margantinis G| title=Relationship between Helicobacter pylori infection and esophageal neoplasia: a meta-analysis. | journal=Clin Gastroenterol Hepatol | year= 2007 | volume= 5 | issue= 12 | pages= 1413-7, 1417.e1-2 | pmid=17997357 | doi=10.1016/j.cgh.2007.08.010 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17997357  }} </ref><ref name="pmid19174811">{{cite journal| author=Wang C, Yuan Y, Hunt RH| title=Helicobacter pylori infection and Barrett's esophagus: a systematic review and meta-analysis. | journal=Am J Gastroenterol | year= 2009 | volume= 104 | issue= 2 | pages= 492-500; quiz 491, 501 | pmid=19174811 | doi=10.1038/ajg.2008.37 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19174811  }} </ref>


==References==
==References==

Latest revision as of 17:14, 21 February 2018

Barrett's Esophagus Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Barrett's Esophagus from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Endoscopic Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Barrett's esophagus risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Barrett's esophagus risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Barrett's esophagus risk factors

CDC on Barrett's esophagus risk factors

Barrett's esophagus risk factors in the news

Blogs on Barrett's esophagus risk factors

Directions to Hospitals TreatingBarrett's esophagus

Risk calculators and risk factors for Barrett's esophagus risk factors


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]

Overview

The most potent risk factor in the development of Barrett's Oesophagus is chronic GERD. Other risk factors include age (>older than 50 years), sex (male), race (caucasian), hiatal hernia, elevated body mass index and intra-abdominal distribution of body fat.

Risk factors

The followings are the risk factors for the Barrett's esophagus;

Protective factors

References

  1. Cook MB, Wild CP, Forman D (2005). "A systematic review and meta-analysis of the sex ratio for Barrett's esophagus, erosive reflux disease, and nonerosive reflux disease". Am J Epidemiol. 162 (11): 1050–61. doi:10.1093/aje/kwi325. PMID 16221805.
  2. Ek WE, Lagergren K, Cook M, Wu AH, Abnet CC, Levine D; et al. (2016). "Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma". Int J Cancer. 138 (5): 1146–52. doi:10.1002/ijc.29863. PMC 4715576. PMID 26414697.
  3. von Schrenck T (2000). "[Diagnosis of gastroesophageal reflux and Barrett esophagus]". Zentralbl Chir. 125 (5): 414–23. PMID 10929625.
  4. Minacapelli CD, Bajpai M, Geng X, Cheng CL, Chouthai AA, Souza R; et al. (2017). "Barrett's metaplasia develops from cellular reprograming of esophageal squamous epithelium due to gastroesophageal reflux". Am J Physiol Gastrointest Liver Physiol. 312 (6): G615–G622. doi:10.1152/ajpgi.00268.2016. PMID 28336546.
  5. Anderson LA, Watson RG, Murphy SJ, Johnston BT, Comber H, Mc Guigan J; et al. (2007). "Risk factors for Barrett's oesophagus and oesophageal adenocarcinoma: results from the FINBAR study". World J Gastroenterol. 13 (10): 1585–94. PMC 4146903. PMID 17461453.
  6. Jacobson BC, Chan AT, Giovannucci EL, Fuchs CS (2009). "Body mass index and Barrett's oesophagus in women". Gut. 58 (11): 1460–6. doi:10.1136/gut.2008.174508. PMC 2763036. PMID 19336423.
  7. Edelstein ZR, Farrow DC, Bronner MP, Rosen SN, Vaughan TL (2007). "Central adiposity and risk of Barrett's esophagus". Gastroenterology. 133 (2): 403–11. doi:10.1053/j.gastro.2007.05.026. PMID 17681161.
  8. Kamat P, Wen S, Morris J, Anandasabapathy S (2009). "Exploring the association between elevated body mass index and Barrett's esophagus: a systematic review and meta-analysis". Ann Thorac Surg. 87 (2): 655–62. doi:10.1016/j.athoracsur.2008.08.003. PMID 19161814.
  9. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. PMID 21376940. Unknown parameter |month= ignored (help)
  10. Whiteman DC, Kendall BJ (2016). "Barrett's oesophagus: epidemiology, diagnosis and clinical management". Med J Aust. 205 (7): 317–24. PMID 27681974.
  11. Rokkas T, Pistiolas D, Sechopoulos P, Robotis I, Margantinis G (2007). "Relationship between Helicobacter pylori infection and esophageal neoplasia: a meta-analysis". Clin Gastroenterol Hepatol. 5 (12): 1413–7, 1417.e1–2. doi:10.1016/j.cgh.2007.08.010. PMID 17997357.
  12. Wang C, Yuan Y, Hunt RH (2009). "Helicobacter pylori infection and Barrett's esophagus: a systematic review and meta-analysis". Am J Gastroenterol. 104 (2): 492–500, quiz 491, 501. doi:10.1038/ajg.2008.37. PMID 19174811.

Template:WH Template:WS