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(/* 2022 ESC Guidelines for the management of patients with ventricular arrythymias and the prevention of sudden cardiac death {{cite journal| author=Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA | display-authors=etal| title=2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. | journal=Eur Heart J | year= 2022 | volume= 43 | issue= 40 | pages= 3997-4126 | pmid=36017572 | doi=10.1093/eurheartj/ehac26...)
 
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==Overview==
==Overview==
Several [[risk calculators]] specific for [[sudden cardiac death]] ([[SCD]]) were proposed in all age groups <ref name="pmid31155932">{{cite journal| author=Wahbi K, Ben Yaou R, Gandjbakhch E, Anselme F, Gossios T, Lakdawala NK | display-authors=etal| title=Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies. | journal=Circulation | year= 2019 | volume= 140 | issue= 4 | pages= 293-302 | pmid=31155932 | doi=10.1161/CIRCULATIONAHA.118.039410 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31155932  }} </ref> <ref name="pmid30915475">{{cite journal| author=Cadrin-Tourigny J, Bosman LP, Nozza A, Wang W, Tadros R, Bhonsale A | display-authors=etal| title=A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. | journal=Eur Heart J | year= 2019 | volume= 40 | issue= 23 | pages= 1850-1858 | pmid=30915475 | doi=10.1093/eurheartj/ehz103 | pmc=6568197 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30915475  }} </ref> <ref name="pmid32418493">{{cite journal| author=Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T | display-authors=etal| title=A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. | journal=Circulation | year= 2020 | volume= 142 | issue= 3 | pages= 217-229 | pmid=32418493 | doi=10.1161/CIRCULATIONAHA.120.047235 | pmc=7365676 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32418493  }} </ref> <ref name="pmid31411652">{{cite journal| author=Norrish G, Ding T, Field E, Ziólkowska L, Olivotto I, Limongelli G | display-authors=etal| title=Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids). | journal=JAMA Cardiol | year= 2019 | volume= 4 | issue= 9 | pages= 918-927 | pmid=31411652 | doi=10.1001/jamacardio.2019.2861 | pmc=6694401 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31411652  }} </ref> <ref name="pmid24126876">{{cite journal| author=O'Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C | display-authors=etal| title=A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD). | journal=Eur Heart J | year= 2014 | volume= 35 | issue= 30 | pages= 2010-20 | pmid=24126876 | doi=10.1093/eurheartj/eht439 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24126876  }} </ref>.  
*Several [[risk calculators]] specific for [[sudden cardiac death]] ([[SCD]]) were proposed in all age groups <ref name="pmid31155932">{{cite journal| author=Wahbi K, Ben Yaou R, Gandjbakhch E, Anselme F, Gossios T, Lakdawala NK | display-authors=etal| title=Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies. | journal=Circulation | year= 2019 | volume= 140 | issue= 4 | pages= 293-302 | pmid=31155932 | doi=10.1161/CIRCULATIONAHA.118.039410 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31155932  }} </ref> <ref name="pmid30915475">{{cite journal| author=Cadrin-Tourigny J, Bosman LP, Nozza A, Wang W, Tadros R, Bhonsale A | display-authors=etal| title=A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. | journal=Eur Heart J | year= 2019 | volume= 40 | issue= 23 | pages= 1850-1858 | pmid=30915475 | doi=10.1093/eurheartj/ehz103 | pmc=6568197 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30915475  }} </ref> <ref name="pmid32418493">{{cite journal| author=Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T | display-authors=etal| title=A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. | journal=Circulation | year= 2020 | volume= 142 | issue= 3 | pages= 217-229 | pmid=32418493 | doi=10.1161/CIRCULATIONAHA.120.047235 | pmc=7365676 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32418493  }} </ref> <ref name="pmid31411652">{{cite journal| author=Norrish G, Ding T, Field E, Ziólkowska L, Olivotto I, Limongelli G | display-authors=etal| title=Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids). | journal=JAMA Cardiol | year= 2019 | volume= 4 | issue= 9 | pages= 918-927 | pmid=31411652 | doi=10.1001/jamacardio.2019.2861 | pmc=6694401 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31411652  }} </ref> <ref name="pmid24126876">{{cite journal| author=O'Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C | display-authors=etal| title=A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD). | journal=Eur Heart J | year= 2014 | volume= 35 | issue= 30 | pages= 2010-20 | pmid=24126876 | doi=10.1093/eurheartj/eht439 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24126876  }} </ref>.  
These tools can be of great help in distinguishing [[patients]] who are at high risk for this condition.
*These tools can be of great help in distinguishing [[patients]] who are at high risk for this condition.




===Screening===
==Screening==
*[[Screening]] in the first relative of [[patients]] with  [[sudden cardiac arrest]] should be done if there is concern about inherited causes of [[cardiac arrest]].
*[[Screening]] in the first relative of [[patients]] with  [[sudden cardiac arrest]] should be done if there is concern about inherited causes of [[cardiac arrest]].
*Several [[SCD]] [[risk calculators]] are available for all age groups <ref name="pmid31155932">{{cite journal| author=Wahbi K, Ben Yaou R, Gandjbakhch E, Anselme F, Gossios T, Lakdawala NK | display-authors=etal| title=Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies. | journal=Circulation | year= 2019 | volume= 140 | issue= 4 | pages= 293-302 | pmid=31155932 | doi=10.1161/CIRCULATIONAHA.118.039410 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31155932  }} </ref> <ref name="pmid30915475">{{cite journal| author=Cadrin-Tourigny J, Bosman LP, Nozza A, Wang W, Tadros R, Bhonsale A | display-authors=etal| title=A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. | journal=Eur Heart J | year= 2019 | volume= 40 | issue= 23 | pages= 1850-1858 | pmid=30915475 | doi=10.1093/eurheartj/ehz103 | pmc=6568197 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30915475  }} </ref> <ref name="pmid32418493">{{cite journal| author=Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T | display-authors=etal| title=A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. | journal=Circulation | year= 2020 | volume= 142 | issue= 3 | pages= 217-229 | pmid=32418493 | doi=10.1161/CIRCULATIONAHA.120.047235 | pmc=7365676 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32418493  }} </ref> <ref name="pmid31411652">{{cite journal| author=Norrish G, Ding T, Field E, Ziólkowska L, Olivotto I, Limongelli G | display-authors=etal| title=Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids). | journal=JAMA Cardiol | year= 2019 | volume= 4 | issue= 9 | pages= 918-927 | pmid=31411652 | doi=10.1001/jamacardio.2019.2861 | pmc=6694401 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31411652  }} </ref> <ref name="pmid24126876">{{cite journal| author=O'Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C | display-authors=etal| title=A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD). | journal=Eur Heart J | year= 2014 | volume= 35 | issue= 30 | pages= 2010-20 | pmid=24126876 | doi=10.1093/eurheartj/eht439 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24126876  }} </ref>
*Several [[SCD]] [[risk calculators]] are available for all age groups <ref name="pmid31155932">{{cite journal| author=Wahbi K, Ben Yaou R, Gandjbakhch E, Anselme F, Gossios T, Lakdawala NK | display-authors=etal| title=Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies. | journal=Circulation | year= 2019 | volume= 140 | issue= 4 | pages= 293-302 | pmid=31155932 | doi=10.1161/CIRCULATIONAHA.118.039410 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31155932  }} </ref> <ref name="pmid30915475">{{cite journal| author=Cadrin-Tourigny J, Bosman LP, Nozza A, Wang W, Tadros R, Bhonsale A | display-authors=etal| title=A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. | journal=Eur Heart J | year= 2019 | volume= 40 | issue= 23 | pages= 1850-1858 | pmid=30915475 | doi=10.1093/eurheartj/ehz103 | pmc=6568197 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30915475  }} </ref> <ref name="pmid32418493">{{cite journal| author=Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T | display-authors=etal| title=A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy. | journal=Circulation | year= 2020 | volume= 142 | issue= 3 | pages= 217-229 | pmid=32418493 | doi=10.1161/CIRCULATIONAHA.120.047235 | pmc=7365676 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32418493  }} </ref> <ref name="pmid31411652">{{cite journal| author=Norrish G, Ding T, Field E, Ziólkowska L, Olivotto I, Limongelli G | display-authors=etal| title=Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids). | journal=JAMA Cardiol | year= 2019 | volume= 4 | issue= 9 | pages= 918-927 | pmid=31411652 | doi=10.1001/jamacardio.2019.2861 | pmc=6694401 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31411652  }} </ref> <ref name="pmid24126876">{{cite journal| author=O'Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C | display-authors=etal| title=A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD). | journal=Eur Heart J | year= 2014 | volume= 35 | issue= 30 | pages= 2010-20 | pmid=24126876 | doi=10.1093/eurheartj/eht439 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24126876  }} </ref>
**[[HCM Risk-Kids Score]] is a validated [[risk calculator]] used for [[patients]] with [[hypertrophic cardiomyopathy]] ([[HCM]]) who are up to 16 years of [[age]].
**LQTS Risk Calculator
**VA calculator
==2022 ESC Guidelines for the management of patients with ventricular arrythymias and the prevention of sudden cardiac death <ref name="pmid36017572">{{cite journal| author=Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA | display-authors=etal| title=2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. | journal=Eur Heart J | year= 2022 | volume= 43 | issue= 40 | pages= 3997-4126 | pmid=36017572 | doi=10.1093/eurheartj/ehac262 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=36017572  }} </ref>==
{|class="wikitable"
|-
| colspan="1" style="text-align:center; background: Silver"|Recommendations for evaluation of relatives of sudden arrhythmic death syndrome decedents''
|-
| colspan="1" style="text-align:center; background:LightGreen"|[[2022 ESC Guidelines Classification Scheme#Classification of Recommendations|Class I]] ''([[2022 ESC Guidelines Classification Scheme#Level of Evidence|Level of Evidence: B]])''
|-
| bgcolor="LightGreen"|
* [[Familial evaluation]] of [[SADS]] decedents is recommended:
** for [[first-degree relatives]]
** for [[relatives who must carry a [[mutation]] based on analysis of the [[family history]]
** for [[relatives]] with suspicious [[symptoms]]
** when the decedent's [[age]] is <50 years, or if there is other circumstantial data or [[family history]] to suggest [[heritable]] [[disease]].
|}
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Latest revision as of 17:33, 21 July 2023

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Edzel Lorraine Co, DMD, MD[3]

Overview


Screening


2022 ESC Guidelines for the management of patients with ventricular arrythymias and the prevention of sudden cardiac death [6]

Recommendations for evaluation of relatives of sudden arrhythmic death syndrome decedents
Class I (Level of Evidence: B)

References

  1. 1.0 1.1 Wahbi K, Ben Yaou R, Gandjbakhch E, Anselme F, Gossios T, Lakdawala NK; et al. (2019). "Development and Validation of a New Risk Prediction Score for Life-Threatening Ventricular Tachyarrhythmias in Laminopathies". Circulation. 140 (4): 293–302. doi:10.1161/CIRCULATIONAHA.118.039410. PMID 31155932.
  2. 2.0 2.1 Cadrin-Tourigny J, Bosman LP, Nozza A, Wang W, Tadros R, Bhonsale A; et al. (2019). "A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy". Eur Heart J. 40 (23): 1850–1858. doi:10.1093/eurheartj/ehz103. PMC 6568197 Check |pmc= value (help). PMID 30915475.
  3. 3.0 3.1 Miron A, Lafreniere-Roula M, Steve Fan CP, Armstrong KR, Dragulescu A, Papaz T; et al. (2020). "A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy". Circulation. 142 (3): 217–229. doi:10.1161/CIRCULATIONAHA.120.047235. PMC 7365676 Check |pmc= value (help). PMID 32418493 Check |pmid= value (help).
  4. 4.0 4.1 Norrish G, Ding T, Field E, Ziólkowska L, Olivotto I, Limongelli G; et al. (2019). "Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids)". JAMA Cardiol. 4 (9): 918–927. doi:10.1001/jamacardio.2019.2861. PMC 6694401 Check |pmc= value (help). PMID 31411652.
  5. 5.0 5.1 O'Mahony C, Jichi F, Pavlou M, Monserrat L, Anastasakis A, Rapezzi C; et al. (2014). "A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD)". Eur Heart J. 35 (30): 2010–20. doi:10.1093/eurheartj/eht439. PMID 24126876.
  6. Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA; et al. (2022). "2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death". Eur Heart J. 43 (40): 3997–4126. doi:10.1093/eurheartj/ehac262. PMID 36017572 Check |pmid= value (help).

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