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Medulloblastoma Microchapters |
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Diagnosis |
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Treatment |
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Case studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Epidemiology and Demographics
Prevalence
Incidence
- The incidence/prevalence of medulloblastoma is approximately per 100,000 individuals worldwide.[1]
Age
- Medulloblastoma is a rare disease that tends to affect children.[1]
- The incidence of medulloblastoma decreases with age; the median age at diagnosis is 5 years.
Gender
Males are more commonly affected with medulloblastoma than females. The male to female ratio is approximately 2 to 1.
Race
Medulloblastomas affect just under 2 people per million per year, and affect children 10 times more than adults.[18] Medulloblastoma is the second most frequent brain tumor in children after pilocytic astrocytoma[19] and the most common malignant brain tumor in children, comprising 14.5% of newly diagnosed cases.[20] In adults, medulloblastoma is rare, comprising fewer than 2% of CNS malignancies.[21]
The rate of new cases of childhood medulloblastoma is higher in males (62%) than females (38%), a feature which is not seen in adults.[18][22] Medulloblastoma and other PNET`s are more prevalent in younger children than older children. Forty percent of medulloblastoma patients are diagnosed before the age of 5, 31% are between the ages of 5 and 9, 18.3% are between the ages of 10 and 14, and 12.7% are between the ages of 15 and 19.[23]
References
- ↑ 1.0 1.1 Medulloblastoma. Wikipedia (2015) https://en.wikipedia.org/wiki/Medulloblastoma#Epidemiology Accessed on November,10 2015