Metampicillin

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Metampicillin
Metampicillin wiki str.png
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
UNII
ChEMBL
E number{{#property:P628}}
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Chemical and physical data
FormulaC17H19N3O4S
Molar mass361.415 g/mol
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Metampicillin (INN) is a penicillin antibiotic. It is prepared by the reaction of ampicillin with formaldehyde, and is hydrolysed in aqueous solution with the formation of ampicillin. Hydrolysis is rapid under acid conditions, e.g., in the stomach, less rapid in neutral media, and incomplete in solutions such as human serum.[1]

References

  1. Sutherland R, Elson S, Croydon EA (1972). "Metampicillin. Antibacterial activity and absorption and excretion in man". Chemotherapy. 17 (3): 145–60. doi:10.1159/000220849. PMID 4556172.

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