Azlocillin

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Azlocillin
Azlocillin.png
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E number{{#property:P628}}
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Chemical and physical data
FormulaC20H23N5O6S
Molar mass461.491 g/mol
3D model (JSmol)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. Azlocillin is similar to mezlocillin and piperacillin. It demonstrates antibacterial activity against a broad spectrum of bacteria, including Pseudomonas aeruginosa and, in contrast to most cephalosporins, exhibits activity against enterococci.

Spectrum of bacterial susceptibility

Azlocillin is considered a broad spectrum antibiotic and can be used against a number of Gram positive and Gram negative bacteria. The following represents MIC susceptibility data for a few medically significant organisms.[1]

  • Escherichia coli 1 μg/mL - 32 μg/mL
  • Haemophilus spp. 0.03 μg/mL - 2 μg/mL
  • Pseudomonas aeruginosa 4 μg/mL - 6.25 μg/mL

References


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