Tazobactam

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Tazobactam
File:Tazobactam structure.svg
Clinical data
ATC code
Identifiers
CAS Number
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC10H12N4O5S
Molar mass300.289 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin® or Zosyn®. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

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