Meningioma other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2] Haytham Allaham, M.D. [3]


Other imaging studies that may be helpful in the diagnosis of meningioma include magnetic resonance (MR) spectroscopy, perfusion MRI, and diffusion MRI. With MR spectroscopy, elevated levels of alanine, choline, and/or lactate could be seen. MR perfusion study could demonstrate an elevated value of relative cerebral blood volume (rCBV).

Other Imaging Findings

Diffusion Weighted MRI

Diffusion MRI may be helpful in the diagnosis of meningioma. Findings on an diffusion MRI suggestive of/diagnostic of meningioma include:[1]

  • Reduced water diffusivity which is seen more in aggressive tumors and atypical/malignant meningiomas
  • A decrease in the apparent diffusion coefficient raises suspicion that a tumor has differentiated to a higher grade on follow up of a benign meningioma.

Magnetic Resonance Spectroscopy

Magnetic resonance spectroscopy may be helpful in the diagnosis of meningioma. Findings on an MR spectroscopy suggestive of/diagnostic of meningioma include:[2]

  • Elevated alanine
  • Elevated choline (Cho)
  • Absent or significantly reduced N-acetylaspartate (NAA)
  • Absent or significantly reduced creatine (Cr)
  • Elevated lactate

Perfusion MRI

Perfusion MRI may be helpful in the diagnosis of meningioma. Findings on an perfusion MRI suggestive of/diagnostic of meningioma include:[3][1]

  • Elevated relative cerebral blood volume (rCBV) value


  1. 1.0 1.1 Saloner D, Uzelac A, Hetts S, Martin A, Dillon W (2010). "Modern meningioma imaging techniques". J Neurooncol. 99 (3): 333–40. doi:10.1007/s11060-010-0367-6. PMC 2945460. PMID 20809250.
  2. Demir MK, Iplikcioglu AC, Dincer A, Arslan M, Sav A (2006). "Single voxel proton MR spectroscopy findings of typical and atypical intracranial meningiomas". Eur J Radiol. 60 (1): 48–55. doi:10.1016/j.ejrad.2006.06.002. PMID 16844335.
  3. Zimny A, Sasiadek M (2011). "Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review". J Neurooncol. 103 (3): 777–83. doi:10.1007/s11060-010-0445-9. PMC 3116130. PMID 21061142.