Acute tubular necrosis screening
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]
Overview
Screening for acute tubular necrosis is usually not recommended for asymptomatic individuals. Screening is usually recommended for patients who are at high risk for developing acute tubular necrosis. Screening evaluation includes measurement of serum creatinine, urine output, blood urea nitrogen, urinary and serum electrolytes.
Screening
- Screening for acute tubular necrosis is usually not recommended for asymptomatic individuals.
- Screening is usually recommended for patients who are at high risk including
- Patients with recent abdominal and cardiac surgery
- Severe volume depletion
- Hemorrhagic shock
- Rhabdomyolysis
- Sepsis
- Severe pancreatitis
- Comorbid conditions (eg, diabetes mellitus, chronic kidney disease, atherosclerosis)
- Patients who are taking nephrotoxic medication
- Screening evaluation includes measurement of the following:[1][2]
- Serum creatinine
- Urine volume
- Blood urea nitrogen (BUN)
- Urine sediment and microscopy
- Urine electrolytes
- Serum electrolytes
- Ultrasonography
References
- ↑ Ostermann M, Joannidis M (September 2016). "Acute kidney injury 2016: diagnosis and diagnostic workup". Crit Care. 20 (1): 299. doi:10.1186/s13054-016-1478-z. PMC 5037640. PMID 27670788.
- ↑ Kellen M, Aronson S, Roizen MF, Barnard J, Thisted RA (January 1994). "Predictive and diagnostic tests of renal failure: a review". Anesth. Analg. 78 (1): 134–42. PMID 8267149.