Acute retinal necrosis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.


Acute retinal necrosis is usually caused by reactivation of latent viruses, including Herpes simplex virus 1 & 2, Varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus.


Acute retinal necrosis (ARN) is usually caused by the reactivation of the following pathogenic viruses in the Herpesviridae family:[1][2][3][4][5][6]

HSV-2 is usually the cause of ARN in individuals younger than 25 years.


  1. Pikkel YY, Pikkel J (2014). "Acute retinal necrosis in childhood". Case Rep Ophthalmol. 5 (2): 138–43. doi:10.1159/000363130. PMC 4049010. PMID 24932179.
  2. Kawaguchi T, Spencer DB, Mochizuki M (2008). "Therapy for acute retinal necrosis". Semin Ophthalmol. 23 (4): 285–90. doi:10.1080/08820530802111192. PMID 18584565.
  3. Usui Y, Goto H (2008). "Overview and diagnosis of acute retinal necrosis syndrome". Semin Ophthalmol. 23 (4): 275–83. doi:10.1080/08820530802111325. PMID 18584564.
  4. Kezuka T, Atherton SS (2007). "Acute retinal necrosis". Chem Immunol Allergy. 92: 244–53. doi:10.1159/000099275. PMID 17264500.
  5. 5.0 5.1 Bonfioli AA, Eller AW (2005). "Acute retinal necrosis". Semin Ophthalmol. 20 (3): 155–60. doi:10.1080/08820530500232027. PMID 16282149.
  6. Chun HL, Missotten T, Salzmann J, Lightman SL (2007). "Acute Retinal Necrosis: Features, Management, and Outcomes". Opthalmology. 114: 756–762. Unknown parameter |Issue= ignored (|issue= suggested) (help)
  7. Ganatra JB, Chandler D, Santos C, Kuppermann B, Margolis TP (2000). "Viral causes of the acute retinal necrosis syndrome". Am. J. Ophthalmol. 129 (2): 166–72. PMID 10682968.
  8. Gartry DS, Spalton DJ, Tilzey A, Hykin PG (1991). "Acute retinal necrosis syndrome". Br J Ophthalmol. 75 (5): 292–7. PMC 1042358. PMID 1645179.
  9. Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D (2014). "Clinical manifestation of self-limiting acute retinal necrosis". Med. Sci. Monit. 20: 2088–96. doi:10.12659/MSM.890469. PMC 4226315. PMID 25356955.

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