Acute lymphoblastic leukemia x ray

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Acute lymphoblastic leukemia Microchapters


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Historical Perspective



Differentiating Acute lymphoblastic leukemia from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


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Bone X Ray

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Case #1

Acute lymphoblastic leukemia x ray On the Web

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]


Bone X-ray in acute lymphoblastic leukemia is characterized by periosteal reaction.


Subtle, patchy sclerotic changes in the distal femoral and proximal tibial metaphysesCase courtesy of Dr Alexandra Stanislavsky,, rID: 49049


  1. Shahnazi M, Khatami A, Shamsian B, Haerizadeh B, Mehrafarin M (2012). "Bony lesions in pediatric acute leukemia: pictorial essay". Iran J Radiol. 9 (1): 50–6. doi:10.5812/iranjradiol.6765. PMC 3522339. PMID 23329962.
  2. Tafaghodi F, Aghighi Y, Rokni Yazdi H, Shakiba M, Adibi A (2009). "Predictive plain X-ray findings in distinguishing early stage acute lymphoblastic leukemia from juvenile idiopathic arthritis". Clin Rheumatol. 28 (11): 1253–8. doi:10.1007/s10067-009-1221-0. PMID 19621208.
  3. Riccio I, Marcarelli M, Del Regno N, Fusco C, Di Martino M, Savarese R; et al. (2013). "Musculoskeletal problems in pediatric acute leukemia". J Pediatr Orthop B. 22 (3): 264–9. doi:10.1097/BPB.0b013e32835d731c. PMID 23407432.
  4. Navarro, Shannon M.; Matcuk, George R.; Patel, Dakshesh B.; Skalski, Matthew; White, Eric A.; Tomasian, Anderanik; Schein, Aaron J. (2017). "Musculoskeletal Imaging Findings of Hematologic Malignancies". RadioGraphics. 37 (3): 881–900. doi:10.1148/rg.2017160133. ISSN 0271-5333.
  5. Angsubhakorn, Natthapon; Suvannasankha, Attaya (2018). "Acute lymphoblastic leukaemia with osteolytic bone lesions: diagnostic dilemma". BMJ Case Reports: bcr-2018–225008. doi:10.1136/bcr-2018-225008. ISSN 1757-790X.
  6. Mostoufi-Moab S, Halton J (2014). "Bone morbidity in childhood leukemia: epidemiology, mechanisms, diagnosis, and treatment". Curr Osteoporos Rep. 12 (3): 300–12. doi:10.1007/s11914-014-0222-3. PMC 4131149. PMID 24986711.

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