Allergic conjunctivitis differential diagnosis: Difference between revisions
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! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings | ! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings | ||
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| [[Bacterial]] [[conjunctivitis]] ||Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref> ||--- | | [[Bacterial]] [[conjunctivitis]] ||Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref> ||Normal [[visual]] [[acuity]]; [[corneal]] involvement may be detected by a [[slit-lamp]] examination<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468 }} </ref>; [[otoscopy]] may detect concurrent [[otitis]] [[media]] in children with [[ear]] [[symptoms]]<ref name="pmid20724317">{{cite journal| author=Pichichero ME| title=Bacterial conjunctivitis in children: antibacterial treatment options in an era of increasing drug resistance. | journal=Clin Pediatr (Phila) | year= 2011 | volume= 50 | issue= 1 | pages= 7-13 | pmid=20724317 | doi=10.1177/0009922810379045 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20724317 }} </ref>||[[Conjunctival]] [[cultures]] || [[Itching]] , [[burning]], [[serous]] or no [[discharge]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref> | ||
|- | |- | ||
| [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468 }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256 }} </ref> ||--------------x---------- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603 }} </ref> || ----------x---------- | | [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468 }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256 }} </ref> ||--------------x---------- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603 }} </ref> || ----------x---------- | ||
Revision as of 18:33, 8 September 2022
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Overview
The differential diagnoses of allergic conjunctivitis include:
Differentiation from other diseases
References
- ↑ 1.0 1.1 Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC (2004). "Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms". BMJ. 329 (7459): 206–10. doi:10.1136/bmj.38128.631319.AE. PMC 487734. PMID 15201195.
- ↑ 2.0 2.1 Azari AA, Barney NP (2013). "Conjunctivitis: a systematic review of diagnosis and treatment". JAMA. 310 (16): 1721–9. doi:10.1001/jama.2013.280318. PMC 4049531. PMID 24150468.
- ↑ Pichichero ME (2011). "Bacterial conjunctivitis in children: antibacterial treatment options in an era of increasing drug resistance". Clin Pediatr (Phila). 50 (1): 7–13. doi:10.1177/0009922810379045. PMID 20724317.
- ↑ Mahmood AR, Narang AT (2008). "Diagnosis and management of the acute red eye". Emerg Med Clin North Am. 26 (1): 35–55, vi. doi:10.1016/j.emc.2007.10.002. PMID 18249256.
- ↑ Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB (2000). "Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis". Invest Ophthalmol Vis Sci. 41 (7): 1818–22. PMID 10845603.
- ↑ 6.0 6.1 6.2 Patel SJ, Lundy DC (2002). "Ocular manifestations of autoimmune disease". Am Fam Physician. 66 (6): 991–8. PMID 12358224.
- ↑ Ghanem VC, Mehra N, Wong S, Mannis MJ (2003). "The prevalence of ocular signs in acne rosacea: comparing patients from ophthalmology and dermatology clinics". Cornea. 22 (3): 230–3. doi:10.1097/00003226-200304000-00009. PMID 12658088.
- ↑ Ozturk T, Kayabasi M, Ozbagcivan O, Ayhan Z, Utine CA (2022). "Common ocular findings in patients with acne rosacea". Int Ophthalmol. 42 (4): 1077–1084. doi:10.1007/s10792-021-02093-5. PMID 34727263 Check
|pmid=value (help).
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings |
|---|---|---|---|---|
| Bacterial conjunctivitis | Bilateral matting of the eyelids in the morning, Mucopurulent discharge, conjunctival hyperemia, no previous history of conjunctivitis[1] | Normal visual acuity; corneal involvement may be detected by a slit-lamp examination[2]; otoscopy may detect concurrent otitis media in children with ear symptoms[3] | Conjunctival cultures | Itching , burning, serous or no discharge[1] |
| Viral conjunctivitis | Thin, watery discharge with intensely hyperemic response[2], periauricular lymphadenopathy[4] | --------------x---------- | Viral cell cultures, PCR for viral DNA detection[5] | ----------x---------- |
| Autoimmune eye disease | Dry or red eyes, foreign-body sensation, pruritus, photophobia[6] | Abnormal Schirmer's test, deranged visual acuity, proptosis, exposure keratitis[6] | Autoimmune panel of blood | Pain, visual changes, complete loss of vision[6] |
| Acne rosacea[7] [8] | Minor irritation, gritty sensation, dryness, blurry vision, blepharitis and conjunctivitis | ------------x----------- | -------------x----------- | Lid margin and conjunctival telangiectasias, eyelid thickening, eyelid crusts and scales, chalazion, hordeolum, punctate epithelial erosions, corneal infiltrates, corneal ulcers, corneal scars, and vascularization |