Allergic conjunctivitis other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sujaya Chattopadhyay, M.D.[2]
Overview
Conjunctival scrapings from the papillae may yield an inflammatory infiltrate. Tear analysis may show raised levels of inflammatory mediators like histamine and prostaglandins.
Other diagnostic studies
- Conjunctival scrapings to demonstrate inflammatory cells and edema within the papillae in GPC and VKC[1].
- Estimation of levels of inflammatory mediators in tears: The tears of VKC patients contain high levels of IgE and mast cell mediators like histamine, leukotrienes, prostaglandins, and kinase[2].
References
- ↑ Irani AM, Butrus SI, Tabbara KF, Schwartz LB (1990). "Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis". J Allergy Clin Immunol. 86 (1): 34–40. doi:10.1016/s0091-6749(05)80120-4. PMID 2196302.
- ↑ Ballow M, Mendelson L (1980). "Specific immunoglobulin E antibodies in tear secretions of patients with vernal conjunctivitis". J Allergy Clin Immunol. 66 (2): 112–8. doi:10.1016/0091-6749(80)90057-3. PMID 7400474.