Adult T-cell leukemia physical examination: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Adult T-cell leukemia}} | {{Adult T-cell leukemia}} | ||
{{CMG}} {{AE}} {{HL}} | {{CMG}}; {{AE}} {{HL}}; {{GRR}} {{Nat}} | ||
==Overview== | ==Overview== | ||
Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for [[maculopapular]] [[rash]], skin [[ulceration]], and [[splenomegaly]]. | Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for [[maculopapular]] [[rash]], skin [[ulceration]], and [[splenomegaly]]. | ||
==Physical Examination== | ==Physical Examination== | ||
The following physical findings may be observed in patients suffering from adult T-cell leukemia:<ref name="pmid18042693">{{cite journal| author=Matutes E| title=Adult T-cell leukaemia/lymphoma. | journal=J Clin Pathol | year= 2007 | volume= 60 | issue= 12 | pages= 1373-7 | pmid=18042693 | doi=10.1136/jcp.2007.052456 | pmc=PMC2095573 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18042693 }} </ref><ref name="pmid19030219">{{cite journal |vauthors=Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J |title=Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis |journal=World J. Gastroenterol. |volume=14 |issue=42 |pages=6584–8 |date=November 2008 |pmid=19030219 |pmc=2773353 |doi= |url=}}</ref><ref name="TaniguchiTakenaka1988">{{cite journal|last1=Taniguchi|first1=Atsuo|last2=Takenaka|first2=Yoshitaka|last3=Noda|first3=Yumiko|last4=Ueno|first4=Yukio|last5=Shichikawa|first5=Kanji|last6=Sato|first6=Kazuto|last7=Miyasaka|first7=Nobuyuki|last8=Nishioka|first8=Kusuki|title=Adult t cell leukemia presenting with prolifeerative synovitis|journal=Arthritis & Rheumatism|volume=31|issue=8|year=1988|pages=1076–1077|issn=00043591|doi=10.1002/art.1780310824}}</ref> | The following physical findings may be observed in patients suffering from adult T-cell leukemia:<ref name="pmid18042693">{{cite journal| author=Matutes E| title=Adult T-cell leukaemia/lymphoma. | journal=J Clin Pathol | year= 2007 | volume= 60 | issue= 12 | pages= 1373-7 | pmid=18042693 | doi=10.1136/jcp.2007.052456 | pmc=PMC2095573 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18042693 }} </ref><ref name="pmid19030219">{{cite journal |vauthors=Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J |title=Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis |journal=World J. Gastroenterol. |volume=14 |issue=42 |pages=6584–8 |date=November 2008 |pmid=19030219 |pmc=2773353 |doi= |url=}}</ref><ref name="TaniguchiTakenaka1988">{{cite journal|last1=Taniguchi|first1=Atsuo|last2=Takenaka|first2=Yoshitaka|last3=Noda|first3=Yumiko|last4=Ueno|first4=Yukio|last5=Shichikawa|first5=Kanji|last6=Sato|first6=Kazuto|last7=Miyasaka|first7=Nobuyuki|last8=Nishioka|first8=Kusuki|title=Adult t cell leukemia presenting with prolifeerative synovitis|journal=Arthritis & Rheumatism|volume=31|issue=8|year=1988|pages=1076–1077|issn=00043591|doi=10.1002/art.1780310824}}</ref><ref name="HermineBouscary1995">{{cite journal|last1=Hermine|first1=Olivier|last2=Bouscary|first2=Didier|last3=Gessain|first3=Antoine|last4=Turlure|first4=Pascal|last5=Leblond|first5=Veronique|last6=Franck|first6=Nathalie|last7=Buzyn-Veil|first7=Agnes|last8=Rio|first8=Bernard|last9=Macintyre|first9=Elisabeth|last10=Dreyfus|first10=Francois|last11=Bazarbachi|first11=Ali|title=Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa|journal=New England Journal of Medicine|volume=332|issue=26|year=1995|pages=1749–1751|issn=0028-4793|doi=10.1056/NEJM199506293322604}}</ref> | ||
===General Appearance=== | ===General Appearance=== | ||
* Adult T-cell leukemia patients often appear [[lethargic]] and [[fatigue|fatigued]] | * Adult T-cell leukemia patients often appear [[lethargic]] and [[fatigue|fatigued]]. | ||
===Vital Signs=== | ===Vital Signs=== | ||
* Low grade [[fever]] | * Low grade [[fever]] | ||
| Line 17: | Line 17: | ||
===HEENT=== | ===HEENT=== | ||
* HEENT examination of patients with adult T-cell leukemia is usually normal. | |||
=== Neck === | |||
* [[Lymphadenopathy]] | * [[Lymphadenopathy]] | ||
===Abdomen=== | ===Lungs=== | ||
* Pulmonary examination of patients with adult T-cell leukemia is usually normal. | |||
=== Heart === | |||
* [[Tachycardia]] | |||
* Abnormal [[heart rhythm]] may be present | |||
=== Abdomen === | |||
* [[Splenomegaly]] | * [[Splenomegaly]] | ||
* [[Hepatomegaly]] | * [[Hepatomegaly]] | ||
=== | ===Back=== | ||
* | * Back examination of patients with adult T-cell leukemia is usually normal. | ||
* | |||
=== Genitourinary === | |||
* Genitourinary examination of patients with adult T-cell leukemia is usually normal. | |||
=== Neuromuscular === | |||
* [[Muscle]] wasting | |||
=== | === Extremities === | ||
* [[Muscle]] wasting | * [[Muscle]] wasting | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
[[Category:Infectious disease]] | |||
[[Category:Oncology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 20:19, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]
Overview
Patients with adult T-cell leukemia usually appear lethargic and fatigued. Physical examination of patients with adult T-cell leukemia is usually remarkable for maculopapular rash, skin ulceration, and splenomegaly.
Physical Examination
The following physical findings may be observed in patients suffering from adult T-cell leukemia:[1][2][3][4]
General Appearance
Vital Signs
- Low grade fever
Skin
- Maculopapular rash
- Skin ulceration
- Leukemia cutis (infiltration of skin by leukemic cells)
HEENT
- HEENT examination of patients with adult T-cell leukemia is usually normal.
Neck
Lungs
- Pulmonary examination of patients with adult T-cell leukemia is usually normal.
Heart
- Tachycardia
- Abnormal heart rhythm may be present
Abdomen
Back
- Back examination of patients with adult T-cell leukemia is usually normal.
Genitourinary
- Genitourinary examination of patients with adult T-cell leukemia is usually normal.
Neuromuscular
- Muscle wasting
Extremities
- Muscle wasting
References
- ↑ Matutes E (2007). "Adult T-cell leukaemia/lymphoma". J Clin Pathol. 60 (12): 1373–7. doi:10.1136/jcp.2007.052456. PMC 2095573. PMID 18042693.
- ↑ Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J (November 2008). "Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis". World J. Gastroenterol. 14 (42): 6584–8. PMC 2773353. PMID 19030219.
- ↑ Taniguchi, Atsuo; Takenaka, Yoshitaka; Noda, Yumiko; Ueno, Yukio; Shichikawa, Kanji; Sato, Kazuto; Miyasaka, Nobuyuki; Nishioka, Kusuki (1988). "Adult t cell leukemia presenting with prolifeerative synovitis". Arthritis & Rheumatism. 31 (8): 1076–1077. doi:10.1002/art.1780310824. ISSN 0004-3591.
- ↑ Hermine, Olivier; Bouscary, Didier; Gessain, Antoine; Turlure, Pascal; Leblond, Veronique; Franck, Nathalie; Buzyn-Veil, Agnes; Rio, Bernard; Macintyre, Elisabeth; Dreyfus, Francois; Bazarbachi, Ali (1995). "Treatment of Adult T-Cell Leukemia-Lymphoma with Zidovudine and Interferon Alfa". New England Journal of Medicine. 332 (26): 1749–1751. doi:10.1056/NEJM199506293322604. ISSN 0028-4793.