Adult T-cell leukemia differential diagnosis: Difference between revisions

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* Adult T-cell leukemia must also be differentiated from other causes of fever, hepatosplenomegaly, and lymph node swelling such as:
* Adult T-cell leukemia must also be differentiated from other causes of [[fever]], [[hepatosplenomegaly]], and [[lymph node]] swelling such as:
:* [[Splenic marginal zone lymphoma]]
:* [[Splenic marginal zone lymphoma]]
:* Nodal marginal zone [[lymphoma]]
:* Nodal marginal zone [[lymphoma]]

Revision as of 23:08, 25 January 2016

Adult T-cell leukemia Microchapters

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Differentiating Adult T-cell leukemia from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Adult T-cell leukemia must be differentiated from other diseases that cause weight loss, night sweats, hepatosplenomegaly, and palpable lymph nodes, such as hairy cell leukaemia, prolymphocytic leukaemia, follicular lymphoma, and mantle cell lymphoma.[1][2]

Differenting Adult T-cell Leukemia from other Diseases


Differential Diagnosis Surface Immunoglobulin CD5 CD22/FMC7 CD23 CD79b CD103

Chronic lymphocytic leukemia

Weakly positive

Positive

Negative

Positive

Negative

Positive/Negative

Prolymphocytic leukemia

Strongly positive

Negative

Positive

Negative

Positive

Negative

Hairy cell leukemia

Strongly positive

Negative

Positive

Negative

Positive/Negative

Positive

Mantle cell lymphoma

Positive

Positive

Strongly positive

Negative

Strongly positive

Negative

Follicular lymphoma

Strongly positive

Negative

Positive

Negative

Strongly positive

Negative


References

  1. 1.0 1.1 Adult T-cell leukemia/lymphoma. Wikipedia (2015) https://en.wikipedia.org/wiki/Adult_T-cell_leukemia/lymphoma Accessed on November, 3 2015
  2. 2.0 2.1 Hoffbrand V, Moss P. Essential Haematology. John Wiley & Sons; 2011

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