Addison's disease historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Addison's disease is named after Dr. Thomas Addison, the British physician who first described the condition in his 1855 On the Constitutional and Local Effects of Disease of the Suprarenal Capsules.[1][2]
Historical perspective
- In 1563, Bartholomeus Eustachius (1520-1574), an anatomy professor at the Collegio della Sapienza in Rome gave a detailed description of the human adrenal glands in his publication "glandulae renibus incumbentes"
- In 1586, Piccolomini, named the glands the suprarenals.
- In 1651, Highmore suggested that the suprarenals act to absorb exudates from the large vessels, and Thomas Wharton in 1656 suggested that the adrenals took something from the nerves and secreted it into the circulation which mirrors the current concept of the neuroendocrine function of the adrenal medulla today.
- In 1716, The Academy of Sciences in Bordeaux conducted an essay competition to determine the function of the adrenal glands, but none of the entries were considered worthy of the prize.
- In 1805, Cuvier defined the medulla and cortex of the adrenal gland,
- In 1852, Albert von Kölliker (1817-1905), gave the first complete description of the microscopic anatomy of the adrenal gland.
- In 1849, Thomas Addison identified the physiological role of the glands and presented a paper on the clinical features of patients with adrenal disease.
- In 1856, Charles Brown-Séquard provided experimental proof of the vital role of the adrenals by performing adrenalectomies (the removal of adrenals) from several animal species.
References
- ↑ Thomas Addison. On The Constitutional And Local Effects Of Disease Of The Supra-Renal Capsules (HTML reprint). London: Samuel Highley.
- ↑ Ten S, New M, Maclaren N (2001). "Clinical review 130: Addison's disease 2001". J. Clin. Endocrinol. Metab. 86 (7): 2909–22. PMID 11443143.