Isopentenyl-diphosphate delta isomerase
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| isopentenyl-diphosphate delta isomerase 1
| |
| Identifiers | |
| Symbol | IDI1 |
| Entrez | 3422 |
| HUGO | 5387 |
| OMIM | 604055 |
| RefSeq | NM_004508 |
| UniProt | Q13907 |
| Other data | |
| EC number | 5.3.3.2 |
| Locus | Chr. 10 p15.3 |
Isopentenyl-diphosphate delta isomerase (or isopentenyl pyrophosphate isomerase) is an enzyme which catalyzes the conversion of 3-isopentenyl pyrophosphate to dimethylallyl pyrophosphate.
External links
Intramolecular oxidoreductases isomerases (EC 5.3) | |
|---|---|
| 5.3.1 - Aldoses/Ketoses | Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase |
| 5.3.3 - C=C | Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase |
| 5.3.4 - S-S | Protein disulfide isomerase (PDIA3) |
| 5.3.99 - other | Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase |
Metabolism: Ketones/mevalonate pathway/cholesterol synthesis | |
|---|---|
| To HMG-CoA | Acetyl-Coenzyme A acetyltransferase - HMG-CoA synthase (regulated step) |
| Ketogenesis | HMG-CoA lyase - 3-hydroxybutyrate dehydrogenase - Thiophorase |
| To Mevalonic acid | HMG-CoA reductase |
| To DMAPP | Mevalonate kinase - Phosphomevalonate kinase - Pyrophosphomevalonate decarboxylase - Isopentenyl-diphosphate delta isomerase |
| To Cholesterols | Dimethylallyltranstransferase - Geranyl pyrophosphate - Farnesyl-diphosphate farnesyltransferase - Squalene monooxygenase - Lanosterol synthase - CYP51A1 |
| To Bile acids | Cholesterol 7 alpha-hydroxylase |
| see also intermediates | |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
