Isopentenyl-diphosphate delta isomerase
| isopentenyl-diphosphate delta isomerase 1
| |
| Identifiers | |
| Symbol | IDI1 |
| Entrez | 3422 |
| HUGO | 5387 |
| OMIM | 604055 |
| RefSeq | NM_004508 |
| UniProt | Q13907 |
| Other data | |
| EC number | 5.3.3.2 |
| Locus | Chr. 10 p15.3 |
Isopentenyl-diphosphate delta isomerase (or isopentenyl pyrophosphate isomerase) is an enzyme which catalyzes the conversion of 3-isopentenyl pyrophosphate to dimethylallyl pyrophosphate.
External links
Intramolecular oxidoreductases isomerases (EC 5.3) | |
|---|---|
| 5.3.1 - Aldoses/Ketoses | Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase |
| 5.3.3 - C=C | Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase |
| 5.3.4 - S-S | Protein disulfide isomerase (PDIA3) |
| 5.3.99 - other | Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase |
Metabolism: Ketones/mevalonate pathway/cholesterol synthesis | |
|---|---|
| To HMG-CoA | Acetyl-Coenzyme A acetyltransferase - HMG-CoA synthase (regulated step) |
| Ketogenesis | HMG-CoA lyase - 3-hydroxybutyrate dehydrogenase - Thiophorase |
| To Mevalonic acid | HMG-CoA reductase |
| To DMAPP | Mevalonate kinase - Phosphomevalonate kinase - Pyrophosphomevalonate decarboxylase - Isopentenyl-diphosphate delta isomerase |
| To Cholesterols | Dimethylallyltranstransferase - Geranyl pyrophosphate - Farnesyl-diphosphate farnesyltransferase - Squalene monooxygenase - Lanosterol synthase - CYP51A1 |
| To Bile acids | Cholesterol 7 alpha-hydroxylase |
| see also intermediates | |
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