Gonadoblastoma physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Gonadoblastoma has no characteristic physical feature, however, any clue to the existence of an intersex disorder must raise the concern for diagnosing the coexisting gonadoblastoma.
Physical Examination
Appearance of the Patient
- Affected individuals may appear phenotypically female or male.
- It is of particular note that clinical presentation may be varied considering the nature of abnormal gonad and the amount of steroid hormone in it.
Skin
- Skin examination of patients with gonadoblastoma is usually normal.
- In phenotypic women, physical examination of patients may be remarkable for hirsutism.[1][2]
HEENT
- HEENT examination of patients with gonadoblastoma is usually normal.
Neck
- Neck examination of patients with gonadoblastoma is usually normal.
Lungs
- Pulmonary examination of patients with gonadoblastoma is usually normal.
Heart
- Cardiovascular examination of patients with gonadoblastoma is usually normal.
Abdomen/Pelvis
- Abdominal examination of patients with gonadoblastoma is usually normal. In some cases, however, a lower abdominal/pelvic mass may be the only clue for the diagnosis.[3]
Back
- Back examination of patients with gonadoblastoma is usually normal.
Genitourinary
- In phenotypic women, physical examination of patients may be remarkable for virilization.[1][2][4]
- In phenotypic men, physical examination suggestive of gonadoblastoma are undescended testes and hypospadias.
Neuromuscular
- Neuromuscular examination of patients with gonadoblastoma is usually normal.
Extremities
- Extremities examination of patients with gonadoblastoma is usually normal.
References
- ↑ 1.0 1.1 Scully RE (1970). "Gonadoblastoma. A review of 74 cases". Cancer. 25 (6): 1340–56. PMID 4193741.
- ↑ 2.0 2.1 Saia, Philip (2018). Clinical gynecologic oncology. Philadelphia, PA: Elsevier. ISBN 978-0-323-40067-1.
- ↑ Gru, Alejandro A.; Williams, Eli S.; Cao, Dengfeng (2017). "Mixed Gonadal Germ Cell Tumor Composed of a Spermatocytic Tumor-Like Component and Germinoma Arising in Gonadoblastoma in a Phenotypic Woman With a 46, XX Peripheral Karyotype". The American Journal of Surgical Pathology. 41 (9): 1290–1297. doi:10.1097/PAS.0000000000000888. ISSN 0147-5185.
- ↑ Bousquet G, Argenson C, Godeneche JL, Cisterne JP, Gazielly DF, Girardin P, Debiesse JL (1986). "[Recovery after aseptic loosening of cemented total hip arthroplasties with Bousquet's cementless prosthesis. Apropos of 136 cases]". Rev Chir Orthop Reparatrice Appar Mot (in French). 72 Suppl 2: 70–4. PMID 3809670.